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RGS6 (NM_004296) Human Untagged Clone
CAT＃: SC117457
RGS6 (untagged)-Human regulator of G-protein signaling 6 (RGS6), transcript variant 2
CNY 3,656.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GAP; HA117; S914 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC117457 sequence for NM_004296 edited (data generated by NextGen Sequencing)
ATGGCTCAAGGATCCGGGGATCAAAGAGCAGTGGGGGTTGCTGACCCAGAGGAGAGTTCT CCAAACATGATCGTTTACTGCAAAATTGAAGACATCATTACAAAGATGCAAGATGACAAG ACAGGGGGTGTGCCCATCAGAACAGTCAAGAGCTTTCTCTCCAAAATCCCCAGTGTCGTC ACAGGTACTGACATTGTGCAGTGGCTTATGAAGAACCTTTCCATTGAGGACCCAGTTGAA GCAATACACTTGGGGAGCCTTATCGCTGCCCAGGGCTACATCTTTCCAATCTCAGACCAT GTTCTCACCATGAAGGATGATGGCACCTTTTATCGTTTCCAGGCTCCGTACTTCTGGCCT TCGAACTGCTGGGAACCTGAAAACACTGACTATGCCATCTATCTCTGTAAGAGGACAATG CAAAATAAAGCAAGGCTGGAACTGGCAGATTATGAAGCAGAAAACTTAGCAAGACTCCAG AGGGCCTTTGCGAGGAAGTGGGAATTCATCTTTATGCAAGCAGAAGCACAAGTAAAGATT GACCGAAAAAAAGACAAGACAGAAAGGAAAATTTTGGATAGTCAAGAACGAGCCTTTTGG GATGTCCACAGGCCTGTGCCAGGCTGTGTGAACACAACAGAAATGGATATCCGAAAATGT CGACGTTTGAAGAATCCACAAAAGGTTAAAAAGTCCGTGTATGGCGTGACTGAAGAGTCC CAGGCACAGAGCCCGGTGCATGTACTCAGCCAACCAATCAGGAAAACAACAAAAGAGGAC ATCCGGAAACAGATAACATTTTTGAACGCACAGATCGACAGACATTGTTTGAAAATGTCC AAAGTGGCTGAAAGTTTAATTGCCTACACGGAACAATATGTGGAATATGACCCTTTGATA ACACCAGCTGAGCCATCCAACCCTTGGATCAGCGATGACGTTGCTTTGTGGGACATAGAG ATGAGCAAAGAGCCCAGCCAACAGCGAGTAAAAAGATGGGGCTTCTCTTTCGATGAGATA TTGAAGGACCAGGTGGGGCGGGACCAGTTTCTACGATTCCTGGAGTCCGAATTCAGTTCA GAAAACCTCAGGTTCTGGCTGGCTGTCCAAGATCTTAAGAAACAACCCCTACAGGATGTG GCCAAGAGGGTAGAAGAAATCTGGCAAGAGTTTCTGGCTCCAGGGGCTCCAAGTGCAATC AACCTGGATTCTCACAGCTATGAGATAACCAGTCAAAATGTCAAAGATGGAGGGAGATAT ACATTTGAAGACGCCCAGGAGCACATCTACAAGCTGATGAAGAGTGACAGCTATGCCCGC TTCCTCCGGTCAAATGCTTACCAGGATTTGCTGCTGGCCAAGAAGAAGGGAAAGTCGCTG GCGGGCAAGCGCCTCACGGGCCTGATGCAGTCCTCCTGA Clone variation with respect to NM_004296.5 546 g=>a >OriGene 5' read for NM_004296 unedited
CTATAGGGCGGCCGCGAATTCGCACGAGGGCCGCGCGTCCTCGCGGGCCCGGGGCTTCGC TCTTCGCTCGCTGAGCCCCTGCGCTCGCCACCACGGAAACTCGGAAAGAGGAGGCGAGGC TGTGGGGAGCGGCGCGGAGACGGACTAGACTTCCCCTCCGCCCCCAAGAGGCTGCCGGTC CCCGGTTCCCTGGGCTTCTCCAGCTTTATCATGAACCTGGCGCAAGGTTGGCTTTAGGAA AAATTCTGGAGCCAGAGGGAGAGTCAAGGCAATTCTTTGGTTGCTAAGTGTGAGTGAAGA CACTCAGGATGGCTCAAGGATCCGGGGATCAAAGAGCAGTGGGGGTTGCTGACCCAGAGG AGAGTTCTCCAAACATGATCGTTTACTGCAAAATTGAAGACATCATTACAAAGATGCAAG ATGACAAGACAGGGGGTGTGCCCATCAGAACAGTCAAGAGCTTTCTCTCCAAAATCCCCA GTGTCGTCACAGGTACTGACATTGTGCAGTGGCTTATGAAGAACCTTTCCATTGAGGACC CAGTTGAAGCAATACACTTGGGGAGCCTTATCGCTGCCCAGGGCTACATCTTTCCAATCT CAGACCATGTTCTCACCATGAAGGATGATGGCACCTTTTATCGTTTCCAGGCTCCGTACT TCTGGCCTTCGAACTGCTGGGAAACCTGAAACACTGACTATGCCATCTATCTCTGNTAGA AGGACATGCAAAATTAAGCAAGGCTGGAACTGGCAGATTATGAAGCAAATACTTAGCAAG ATCCAAAGGGCCTTTGCGAGGAAGTGGGATTCATCTTATGCAAGCAGATCCCAGTTAAGA TGGCCGAAAAAGACAGACAGAAGGAAATTTGGATAGT >OriGene 3' read for NM_004296 unedited
CTATGGACCGGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTGGGTTCAA GTCATTTATTTTTAAACTGTACCAGCATGTTTGGTTCTGGGGTCCAATTCCCACATTCCA GAAAAATAAACTAAAGAGAACCACATGCACTAAGAGGAGGCCCTTCCGATGAGTCCGCGA TCATGCGGTGAGTGGGCTTAAAGTATACAACAGGGACCCCTGGTATGGAGCAGGGCCTTC CCTTCCCAGACAGCTGACAGCAGCTGGCTCTGAGCCCTCATCGGGGCTGGGGAGAGGGCC AAGCCCTGGTCATTTGGACCCTGTCCCCGTATAGACCCGGGCCCTTTATTGCTACATTTG CTACTTTGCTACTTTATGGCCCCTGGGTCTAGCCCAGGGGATGCCTTATCACTGGGTGGC ACTAAAGAGTAGGCTGCTGGCATCTGCTGATGCTATGGTTACACGAGCACAGGCCCCTCT TCAGAGGGCCCCATGGTGAGCTATTACCGACTCGTATGGCCCCTATTCAACTGACCCCCA TGGCCTTTGCTACATATTCAACTCGGCGCCACCCCCCTTTTGAAGCTGGTGGCGCATTAT CTCCCCCCCACTCCACAGTTCCCACCTCCTGTACCTTGCAGCAAACCTTTCTTAACTACA ATCTTGCAGGGCCCAACGGCACCAGAGCCCTTAATCCTCTTCCCTTTCCTGGGAAGGCTC TCCTGGCGCGGGCTTTCCGACCCCATTCTCTGGCACCCAACCCGACGGCGCCCCTCAAGG AAAACTTCACCTTCTTCATGAACCAGGTGACCACCCGGCGGCCCCTTCTTGCTCAACGCC CGCTCGCGCCGGAATTTCCAACCCCACCATTCCCCCCCGCACCCACCACTGGAATCTGCC CCCCGCGATTCCACTCTCCACACCCGCCCACACCTGACAAAGCTACTCCAGTACGTCTGA CCCCTTCTCACAACCCTAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004296 |
| Insert Size | 4700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_004296.3, NP_004287.3 |
| RefSeq Size | 3105 bp |
| RefSeq ORF | 1419 bp |
| Locus ID | 9628 |
| UniProt ID | P49758 |
| Domains | RGS, DEP, G-gamma |
| Protein Families | Druggable Genome |
| Gene Summary | This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Many alternatively spliced transcript variants encoding different isoforms with long or short N-terminal domains, complete or incomplete GGL domains, and distinct C-terminal domains, have been described for this gene, however, the full-length nature of some of these variants is not known.[provided by RefSeq, Mar 2011] Transcript Variant: This variant (2) lacks the in-frame penultimate coding exon compared to variant 1. This results in a shorter isoform (2, also known as RGS6Lalpha2), missing an 18 aa protein segment compared to isoform 1. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC211189 | RGS6 (Myc-DDK-tagged)-Human regulator of G-protein signaling 6 (RGS6), transcript variant 2 |
CNY 3,656.00 |
|
| RC211189L3 | Lenti ORF clone of Human regulator of G-protein signaling 6 (RGS6), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC211189L4 | Lenti ORF clone of Human regulator of G-protein signaling 6 (RGS6), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG211189 | RGS6 (tGFP-tagged) - Human regulator of G-protein signaling 6 (RGS6), transcript variant 2 |
CNY 4,370.00 |
