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FCGRT (NM_004107) Human Untagged Clone
CAT＃: SC117595
FCGRT (untagged)-Human Fc fragment of IgG, receptor, transporter, alpha (FCGRT), transcript variant 2
CNY 5,488.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | alpha-chain; FCRN |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC117595 sequence for NM_004107 edited (data generated by NextGen Sequencing)
ATGGGGGTCCCGCGGCCTCAGCCCTGGGCGCTGGGGCTCCTGCTCTTTCTCCTTCCTGGG AGCCTGGGCGCAGAAAGCCACCTCTCCCTCCTGTACCACCTTACCGCGGTGTCCTCGCCT GCCCCGGGGACTCCTGCCTTCTGGGTGTCCGGCTGGCTGGGCCCGCAGCAGTACCTGAGC TACAATAGCCTGCGGGGCGAGGCGGAGCCCTGTGGAGCTTGGGTCTGGGAAAACCAGGTG TCCTGGTATTGGGAGAAAGAGACCACAGATCTGAGGATCAAGGAGAAGCTCTTTCTGGAA GCTTTCAAAGCTTTGGGGGGAAAAGGTCCCTACACTCTGCAGGGCCTGCTGGGCTGTGAA CTGGGCCCTGACAACACCTCGGTGCCCACCGCCAAGTTCGCCCTGAACGGCGAGGAGTTC ATGAATTTCGACCTCAAGCAGGGCACCTGGGGTGGGGACTGGCCCGAGGCCCTGGCTATC AGTCAGCGGTGGCAGCAGCAGGACAAGGCGGCCAACAAGGAGCTCACCTTCCTGCTATTC TCCTGCCCGCACCGCCTGCGGGAGCACCTGGAGAGGGGCCGCGGAAACCTGGAGTGGAAG GAGCCCCCCTCCATGCGCCTGAAGGCCCGACCCAGCAGCCCTGGCTTTTCCGTGCTTACC TGCAGCGCCTTCTCCTTCTACCCTCCGGAGCTGCAACTTCGGTTCCTGCGGAATGGGCTG GCCGCTGGCACCGGCCAGGGTGACTTCGGCCCCAACAGTGACGGATCCTTCCACGCCTCG TCGTCACTAACAGTCAAAAGTGGCGATGAGCACCACTACTGCTGCATTGTGCAGCACGCG GGGCTGGCGCAGCCCCTCAGGGTGGAGCTGGAATCTCCAGCCAAGTCCTCCGTGCTCGTG GTGGGAATCGTCATCGGTGTCTTGCTACTCACGGCAGCGGCTGTAGGAGGAGCTCTGTTG TGGAGAAGGATGAGGAGTGGGCTGCCAGCCCCTTGGATCTCCCTTCGTGGAGACGACACC GGGGTCCTCCTGCCCACCCCAGGGGAGGCCCAGGATGCTGATTTGAAGGATGTAAATGTG ATTCCAGCCACCGCCTGA Clone variation with respect to NM_004107.4 >OriGene 5' read for NM_004107 unedited
NTTGTTCGAATTTTGGTATACGACTCACTATAGGGCGGCCGGCGAATCGGCACGAGCCGC AGGCAGGAAGGGAGCGAGGCTGAAGGGAACGTCGTCCTCTCAGCATGGGGGTCCCGCGGC CTCAGCCCTGGGCGCTGGGGCTCCTGCTCTTTCTCCTTCCTGGGAGCCTGGGCGCAGAAA GCCACCTCTCCCTCCTGTACCACCTTACCGCGGTGTCCTCGCCTGCCCCGGGGACTCCTG CCTTCTGGGTGTCCGGCTGGCTGGGCCCGCAGCAGTACCTGAGCTACAATAGCCTGCGGG GCGAGGCGGAGCCCTGTGGAGCTTGGGTCTGGGAAAACCAGGTGTCCTGGTATTGGGAGA AAGAGACCACAGATCTGAGGATCAAGGAGAAGCTCTTTCTGGAAGCTTTCAAAGCTTTGG GGGGAAAAGGTCCCTACACTCTGCAGGGCCTGCTGGGCTGTGAACTGGGCCCTGACACAC CTCCTCGTGGCCCACCGCCAAGTTCGCCCTGAACGGCGAGGAGTTCATGAATTTCGACCT CAAGCAGGGCCCTGGGGTGGGGGACTGCCCCGAGGCCCTGGCTATCAGTCAGCGGTGGCA GCAGCAGGACAAGGCGGCCAACAAGGAGCTCACCTTCCTGCTATTCTCCTGCCCGCACCG CCTGCGGGAGCACCTGGAAGAGGGGCCCGCCGGAACCCTGGAGTGGGAAAGGAGCCCCCT CCATGCGCCTGAAGGCCCGACCCAGCAGCCCTGGCTTTTTCCGTGCTTACCTGCAGCGCC TTCTCCTTCTACCCTNCGGAGCTGCACTTTCGGGTCCTGCGGAATGGGCTGGCCGTTGCA CCGGCCAGGGGACTTCGGCCCCACGGGGACGGTCCTTCCCGCTTCGTCGCCCTAACGTCA AAGCGGCCGAGATCCCCCTCTGCTGCATTGGCCCCAGGGGGCTTGGCC >OriGene 3' read for NM_004107 unedited
ATGAACCGCGGCACGCAATCTAGTAGTCGAGNNNTTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTGGGGCCCCAAACTTGT GTTTTTTTTTGGGGGGGAAAAACCCCCTTTTTTTTTAGGGGGGGAAATTGGGGCAAACCA CAGGACGGGGCTCCAAAGGGAGAAAAATTAGCCCCAAAACCCCTTTTGGAGGCTAAAAAA TCCCAGGGTTCCAAAAGGTCTAAAAAAAAAAAAGGGGCCTGACTACTTTCTTTTTTAACA ACCAAAATGGCGGATGGCCAGGCGGGGGCGGAAATCAAATTTACTTCCTTAAAAAAAAAA TCCGGGCCCCCCCCTGGGGGGGGCAGAAAAACCCCGGGGTCTCCCCCAAAAAGGGAAACC CAAGGGGGTGGAACCCCATTCTTTTTTTTTTTCAAAAAAAAAATTCCTCCTAAAGCCCTT GCCGGGATTAACAAAACCCCGTTAACAATCCCCCCCCCAACCCCGGAGGATTGGGCTGGA AATTCCACCTCCACCCTGAGGGGCTGCCCCACCCCCGGGTGTTGAAAAATGAAAAAGTAG GGGGCCTCATCCCCCCTTTTAACTGTAAAGGACAACAAGGCGGGAAAGGACCCGCCCTTG GGGGGGCCAAATTCACCCTTGGCGGGGCCAGGGGCCACCCCATTCCGAAGAACCCAATTT CCCCCTCCGAAGGAAAAAAGAAAAGGCCCTCCAGGTAACCCGGAAAAACCAGGCTGTTGG GTCGGCCCTAAGGCACATGGAGGGGGCCTCCTCCCATCAAGGTTCCGGGCCCCTTCAAAG GCTCCCCGGGCGGGGGGGAGAAAATACAGAAGGGGCCTCTTTTGCCCCTTTTCTTTTTTC CCCCTTAATAAACCAGGCCTGGGCAACCCCCCCAGGGCCGTGTTAGGGGAATTTAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_004107 |
| Insert Size | 1410 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_004107.3, NP_004098.1 |
| RefSeq Size | 1510 bp |
| RefSeq ORF | 1098 bp |
| Locus ID | 2217 |
| UniProt ID | P55899 |
| Domains | MHC_I, IGc1 |
| Protein Families | Transmembrane |
| Gene Summary | This gene encodes a receptor that binds the Fc region of monomeric immunoglobulin G. The encoded protein transfers immunoglobulin G antibodies from mother to fetus across the placenta. This protein also binds immunoglobulin G to protect the antibody from degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009] Transcript Variant: This variant (2) has an alternate 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Cross-species analysis of Fc engineered anti-Lewis-Y human IgG1 variants in human neonatal receptor transgenic mice reveal importance of S254 and Y436 in binding human neonatal Fc receptor
,Burvenich, IJ;Farrugia, W;Lee, FT;Catimel, B;Liu, Z;Makris, D;Cao, D;O'Keefe, GJ;Brechbiel, MW;King, D;Spirkoska, V;Allan, LC;Ramsland, PA;Scott, AM;,
MAbs
,PubMed ID 27030023
[FCGRT]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC200364 | FCGRT (Myc-DDK-tagged)-Human Fc fragment of IgG, receptor, transporter, alpha (FCGRT), transcript variant 2 |
CNY 5,488.00 |
|
| RC200364L1 | Lenti ORF clone of Human Fc fragment of IgG, receptor, transporter, alpha (FCGRT), transcript variant 2, Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC200364L2 | Lenti ORF clone of Human Fc fragment of IgG, receptor, transporter, alpha (FCGRT), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RC200364L3 | Lenti ORF clone of Human Fc fragment of IgG, receptor, transporter, alpha (FCGRT), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC200364L4 | Lenti ORF clone of Human Fc fragment of IgG, receptor, transporter, alpha (FCGRT), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG200364 | FCGRT (tGFP-tagged) - Human Fc fragment of IgG, receptor, transporter, alpha (FCGRT), transcript variant 2 |
CNY 7,088.00 |
