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RPTP mu (PTPRM) (NM_002845) Human Untagged Clone
CAT＃: SC118369
PTPRM (untagged)-Human protein tyrosine phosphatase, receptor type, M (PTPRM), transcript variant 2
CNY 9,944.00
货期*
现货
规格
Product images
经常一起买 (4)
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | hR-PTPu; PTPRL1; R-PTP-MU; RPTPM; RPTPU |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_002845 edited
CGGCACCAGGTCTCTCCTCGCTGCCTCGGAACCAAAGCTCCCGGCCCCCTCCGCCCTCGC GCGCCCACCCACCGCCGCCGGGGAGCGGCCCGGCGCGCACTCAGCACCATGAGGGGACTT GGGACTTGCCTGGCGACTTTGGCCGGACTTTTGCTAACTGCGGCGGGCGAGACGTTCTCA GGTGGCTGCCTCTTTGATGAGCCGTATAGCACATGTGGATATAGTCAATCTGAAGGTGAT GACTTCAATTGGGAGCAAGTGAACACCTTGACTAAACCGACTTCTGATCCATGGATGCCA TCAGGTTCTTTCATGCTGGTGAATGCCTCTGGGAGACCTGAGGGGCAGAGAGCCCACCTG CTCTTACCCCAACTTAAAGAAAATGACACCCACTGCATCGATTTTCACTATTTTGTGTCC AGCAAGAGTAATTCTCCTCCGGGGTTACTCAATGTCTACGTGAAGGTCAATAACGGGCCA CTGGGGAATCCTATCTGGAATATATCTGGAGACCCAACACGTACATGGAACAGGGCAGAA CTGGCCATTAGTACTTTCTGGCCTAACTTTTATCAGGTGATTTTTGAAGTGATAACTTCT GGACATCAAGGCTATCTCGCTATCGATGAGGTGAAGGTGTTAGGACATCCATGTACCAGG ACTCCTCACTTCCTGCGGATTCAGAATGTGGAAGTTAATGCTGGCCAGTTTGCTACCTTC CAGTGCAGTGCCATCGGCAGGACCGTGGCAGGAGACAGGCTCTGGTTACAGGGCATTGAT GTGCGAGATGCTCCTCTGAAGGAAATCAAGGTGACCAGCTCCCGACGCTTCATTGCTTCA TTTAATGTTGTGAATACCACCAAACGAGATGCTGGAAAGTACCGCTGCATGATTCGCACT GAAGGAGGTGTTGGAATATCAAACTATGCAGAGTTGGTAGTTAAAGAACCACCCGTTCCT ATTGCCCCACCTCAGCTCGCCTCTGTAGGAGCCACCTACCTGTGGATACAGCTCAACGCC AACTCCATCAATGGGGATGGGCCCATTGTGGCCCGAGAGGTGGAGTACTGCACGGCCAGT GGGAGCTGGAATGACCGGCAGCCAGTCGATTCCACGAGCTATAAAATTGGACACCTTGAC CCAGATACAGAATATGAGATTAGTGTGCTCCTGACCAGGCCAGGGGAGGGTGGCACTGGC TCTCCTGGTCCAGCTCTCAGGACAAGAACAAAGTGTGCTGATCCCATGCGAGGCCCAAGA AAACTAGAAGTAGTGGAGGTCAAATCTCGGCAAATCACTATCCGCTGGGAGCCATTTGGA TATAATGTAACTCGTTGCCACAGTTATAATCTCACTGTCCACTACTGTTACCAAGTTGGA GGACAAGAACAAGTGCGAGAAGAAGTAAGCTGGGATACAGAAAATTCACACCCTCAACAC ACGATCACTAACCTGTCACCATACACCAATGTCAGTGTGAAACTGATCCTCATGAACCCA GAGGGCCGGAAGGAAAGCCAAGAACTCATAGTGCAGACAGATGAAGACCTCCCAGGTGCT GTTCCCACTGAATCCATACAAGGAAGTACCTTTGAAGAGAAGATATTTCTTCAGTGGAGA GAACCAACTCAAACATATGGTGTAATCACTTTATATGAGATCACCTACAAAGCAGTCAGT TCCTTTGACCCAGAAATAGATTTATCCAATCAGAGTGGAAGAGTTTCAAAGCTGGGAAAT GAAACCCATTTTCTGTTTTTTGGACTGTATCCGGGGACCACATACTCCTTTACCATCCGA GCTAGCACAGCTAAGGGTTTTGGGCCTCCAGCAACAAACCAGTTCACCACCAAAATATCA GCACCCTCTATGCCAGCTTATGAACTTGAGACACCTTTGAATCAAACTGACAATACCGTG ACAGTCATGCTGAAACCTGCCCACAGCAGAGGAGCACCTGTCAGTGTCTATCAAATAGTT GTTGAGGAAGAACGTCCTCGAAGAACTAAAAAGACGACAGAAATCTTAAAGTGCTACCCA GTGCCAATTCACTTCCAGAATGCTTCTCTGCTGAACTCACAGTACTACTTTGCTGCAGAA TTTCCTGCAGACAGCCTCCAAGCTGCGCAGCCTTTTACAATTGGTGATAATAAGACATAT AATGGATACTGGAACACTCCCCTTCTCCCCTATAAAAGCTACAGAATTTATTTCCAAGCT GCTAGTAGAGCCAATGGGGAAACCAAAATAGACTGTGTCCAAGTGGCCACAAAAGGAGCT GCCACTCCGAAACCAGTCCCAGAACCCGAGAAACAGACAGACCATACAGTTAAAATTGCT GGAGTCATCGCGGGCATCTTGCTGTTCGTGATTATATTTCTTGGAGTTGTGTTGGTAATG AAGAAAAGGAAACTGGCCAAGAAGCGGAAAGAGACCATGAGCAGCACCCGACAGGAGATG ACTGTGATGGTGAACTCAATGGACAAGAGCTATGCTGAGCAGGGCACAAACTGCGACGAG GCTTTCTCATTCATGGACACGCACAATCTGAATGGGAGATCTGTGTCTTCACCATCGTCC TTCACAATGAAAACAAATACACTGAGCACATCGGTGCCTAATTCCTATTACCCAGATGAA ACCCACACAATGGCCAGCGATACCAGCAGCCTGGTGCAGTCCCATACTTACAAGAAGCGA GAGCCGGCCGACGTGCCCTATCAGACTGGGCAGCTCCACCCCGCCATCCGGGTGGCAGAC CTCCTTCAGCACATCACACAGATGAAGTGTGCGGAGGGCTACGGCTTCAAGGAGGAATAC GAGAGCTTCTTTGAAGGGCAGTCTGCACCATGGGACTCGGCTAAGAAAGATGAGAACAGA ATGAAGAACAGATACGGGAATATCATTGCATACGATCATTCCCGAGTGAGGCTGCAGACA ATAGAAGGAGACACAAACTCAGACTATATCAATGGCAATTATATCGATGGTTATCATCGA CCCAATCATTACATTGCTACCCAAGGGCCAATGCAGGAAACCATCTATGACTTCTGGAGG ATGGTGTGGCACGAAAACACTGCAAGTATCATCATGGTGACCAATCTTGTGGAAGTGGGA AGGGTCAAATGCTGCAAATACTGGCCAGATGACACAGAGATATATAAAGACATTAAAGTT ACCCTAATAGAAACAGAACTACTGGCAGAATATGTGATAAGAACATTTGCTGTTGAAAAG AGAGGTGTGCATGAAATCCGAGAGATCAGACAGTTTCACTTCACTGGCTGGCCGGATCAT GGGGTCCCCTACCATGCCACCGGCCTGCTGGGATTCGTGCGGCAAGTCAAGTCCAAGAGC CCGCCCAGTGCAGGCCCACTGGTGGTGCACTGCAGTGCTGGTGCAGGGAGGACTGGCTGT TTCATCGTCATTGATATCATGTTGGACATGGCCGAAAGGGAAGGGGTCGTAGACATCTAC AACTGCGTCAGGGAGCTGCGGTCACGGAGGGTGAACATGGTGCAAACAGAGGAGCAGTAT GTGTTTATCCACGATGCGATCCTGGAAGCCTGTCTTTGTGGGGACACCTCTGTGCCTGCT TCCCAAGTTAGGTCTCTGTATTATGACATGAACAAACTGGATCCACAGACAAACTCAAGC CAGATTAAAGAGGAATTCCGGACGCTAAACATGGTGACACCAACGCTGCGAGTAGAGGAC TGCAGCATCGCACTGTTGCCCCGGAACCATGAGAAAAACCGGTGCATGGACATCCTGCCC CCAGACCGCTGCCTGCCCTTCCTCATCACCATCGATGGGGAGAGCAGCAACTACATCAAT GCTGCCCTCATGGACAGCTATAAACAGCCTTCAGCTTTTATAGTCACCCAGCATCCTTTG CCAAACACAGTGAAAGACTTTTGGAGACTGGTCCTGGATTATCACTGCACATCCGTAGTT ATGCTAAATGATGTGGATCCTGCCCAGTTGTGTCCACAGTACTGGCCAGAAAACGGAGTA CACAGACACGGCCCCATCCAGGTGGAATTTGTCTCTGCTGACCTGGAAGAGGACATCATC AGCAGGATATTCCGCATTTACAATGCCGCCAGACCCCAAGATGGATATCGGATGGTGCAG CAATTCCAGTTCCTGGGCTGGCCGATGTACAGGGACACACCAGTGTCTAAGCGCTCCTTC TTGAAGCTCATTCGCCAGGTGGACAAGTGGCAAGAGGAATACAATGGCGGGGAAGGCCGC ACCGTTGTGCACTGCTTGAACGGGGGAGGCCGCAGTGGGACGTTCTGCGCCATCAGCATC GTATGTGAGATGCTCCGGCACCAGAGAACCGTGGATGTCTTTCACGCTGTGAAGACACTG AGGAACAACAAGCCCAACATGGTCGACCTCCTGGATCAGTACAAGTTCTGCTACGAGGTG GCCCTGGAATACTTGAATTCTGGCTGATGGTGTAAACAGCTCTGCAAACAATCCCTTTCA TACCACAAAGCCAAGACGTTCCATGGTATTTGTGCAAAAGAGATGAAGACTTCTCAATAT GCTTATTTTGCTTTGCATAATTGGCTCTTTTTAAGAGCCCAAGAAAGTGTTTCTAAAATT GCTTGCACTGCCCAATCCCAGTAATGCTGCTGCCTGACAGAAACACACACACAGCCACAG TTGCCAAATCCCGTACTCCTTGCCACCGGCTTCCTAGAGCAGCGTAGACAGCTGGTAAAC TGAAGAGCACAACTATATTCTTATGAAGGAATTTGTACCTTTGGGGTATTATTTTGTGGC CCGTGACCCTCGTTATTGTTACAGCTGAGTGTATGTTTTTGTTCTGTGGAGAATGCTATC TGGCATTATGGTAATATATTATTTTAGGTAATATTTGTACTTTAACATGTTGCATAATAT ATGCTTATGTAGCTTTCCAGGACTAACAGATAAATGTGTAATGAACAAAGATATGTTGTA TGAGTCGTCGTTTCTGTCAGATTTGTATTGTTTCCAAGGGAAAAGCTTGGGGGAGGACTC AGTTCACAAAATGCAAAACTCAACGATCAGATTCACGGACCCAGAGAATGACGGAGTTTA TATTGTAAATATTTTTGATTTCATCAAATTATTTATTCATTAAAAGAAATTTTTGTGAAG CACAGTGAGTGACAATCATTTTTCTTAAGGCCTGGAAACGATTTTCTGTATGATGTTAC >OriGene 5' read for NM_002845 unedited
NNGGGGTGCAGATTTGTATACGACTCACTATAGGCGGCCGCGAATCGGCACCAGGTCTCT CCTCGCTGCCTCGGAACCAAAGCTCCCGGCCCCCTCCGCCCTCGCGCGCCCACCCACCGC CGCCGGGGAGCGGCCCGGCGCGCACTCAGCACCATGAGGGGACTTGGGACTTGCCTGGCG ACTTTGGCCGGACTTTTGCTAACTGCGGCGGGCGAGACGTTCTCAGGTGGCTGCCTCTTT GATGAGCCGTATAGCACATGTGGATATAGTCAATCTGAAGGTGATGACTTCAATTGGGAG CAAGTGAACACCTTGACTAAACCGACTTCTGATCCATGGATGCCATCAGGTTCTTTCATG CTGGTGAATGCCTCTGGGAGACCTGAGGGGCAGAGAGCCCACCTGCTCTTACCCCAACTT AAAGAAAATGACACCCACTGCATCGATTTTCACTATTTTGTGTCCAGCAAGAGTAATTCT CCTCCGGGGTTACTCAATGTCTACGTGAAGGTCAATAACGGGCCACTGGGGAATCCTATC TGGAATATATCTGGAGACCCAACACGTACATGGAACAGGGCAGAACTGGCCATTAGTACT TTCTGGCCTAACTTTTATCAGGTGATTTTTGAAGTGATAACTTCTGGACATCAAGGCTAT CTCGCTATCGATGAGGTGAAGGTGTTAGGACATCCATGTACCAGGACTCCTCACTTCCTG CGGATTCAGAATGTGGAAGTTAATGCTGGCCAGTTTGCTACCTTCCAGTGCAGTGCCATC GGCAGGACCGTGNGCAGAGACAGGCTCTGGTTACAGGGCATTGATGTGCGAGATGCTCCT CTGAAGGAAACAAGGTGACAGCTCCCGCGCTTCATGCTTATTTAATGTTGNGAATACACC AAACGAGAGC >OriGene 3' read for NM_002845 unedited
GGTTACCAAAACGCCCTCGAGATCGAGTTTTTTTTTTTTTTTTTTAACGGGTCATCTTTT TATTGAGNATGAGAAATTCACATATTGTAACATCATACAGAAAATCGTTTCCAGGCCTTA AGAAAAATGATTGTCACTCACTGTGCTTCACAAAAATTTCTTTTAATGAATAAATAATTT GATGAAATCAAAAATATTTACAATATAAACTCCGTCATTCTCTGGGTCCGTGAATCTGAT CGTTGAGTTTTGCATTTTGTGAACTGAGTCCTCCCCCAAGCTTTTCCCTTGGAAACAATA CAAATCTGACAGAAACGACGACTCATACAACATATCTTTGTTCATTACACATTTATCTGT TAGTCCTGGAAAGCTACATAAGCATATATTATGCAACATGTTAAAGTACAAATATTACCT AAAATAATATATTACCATAATGCCAGATAGCATTCTCCACAGAACAAAAACATACACTCA GCTGTAACAATAACGAGGGTCACGGGCCACAAAATAATACCCCAAAGGTACAAATTCCTT CATAAGAATATAGTTGTGCTCTTCAGTTTACCAGCTGTCTACGCTGCTCTAGGAAGCCGG TGGCAAGGAGTACGGGATTTGGCAACTGTGGCTGTGTGTGTGTTTCTGTCAGGCAGCAGC ATTACTGGGATTGGGCAGTGCAAGCAATTTTAGAAACACTCTCTTGAGCTCTTAAAAAGA CCCAATTTGCAAACCAAAATAAGCATATTGAGAAGTCTTCATCTCTTTTGCACAAATACC ATGGAACGATTTGGCTTTGTGGTTTGAAAAGGATTGTTTGTATACTTGTCACCCCTCTCC CCTATTCAAGTTTTTCAGGCCACCTCCCCACATAACTGCACTGTCCCACAAGATCGCCTT GTGGGTCTAATATTTCCTTTGTTCATTCACTCGAAAACATCTTCGCTCTCTCATGCCTCT ATTTACCCTCAATATATN |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002845 |
| Insert Size | 4700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_002845.2, NP_002836.2 |
| RefSeq Size | 5065 bp |
| RefSeq ORF | 4359 bp |
| Locus ID | 5797 |
| UniProt ID | P28827 |
| Domains | Y_phosphatase, MAM, PTPc_motif, IG, FN3 |
| Protein Families | Druggable Genome, Phosphatase, Transmembrane |
| Protein Pathways | Adherens junction, Cell adhesion molecules (CAMs) |
| Gene Summary | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP has been shown to mediate cell-cell aggregation through the interaction with another molecule of this PTP on an adjacent cell. This PTP can interact with scaffolding protein RACK1/GNB2L1, which may be necessary for the downstream signaling in response to cell-cell adhesion. Alternative splicing results in multiple transcripts encoding distinct isoforms. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (2) lacks two adjacent in-frame exons in the 5' coding region, compared to variant 1, resulting in a shorter protein (isoform 2), compared to isoform 1. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC219912 | PTPRM (Myc-DDK-tagged)-Human protein tyrosine phosphatase, receptor type, M (PTPRM), transcript variant 2 |
CNY 14,440.00 |
|
| RC219912L3 | Lenti-ORF clone of PTPRM (Myc-DDK-tagged)-Human protein tyrosine phosphatase, receptor type, M (PTPRM), transcript variant 2 |
CNY 16,340.00 |
|
| RC219912L4 | Lenti-ORF clone of PTPRM (mGFP-tagged)-Human protein tyrosine phosphatase, receptor type, M (PTPRM), transcript variant 2 |
CNY 16,340.00 |
|
| RG219912 | PTPRM (tGFP-tagged) - Human protein tyrosine phosphatase, receptor type, M (PTPRM), transcript variant 2 |
CNY 12,528.00 |
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