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MAFG (NM_002359) Human Untagged Clone
CAT＃: SC118695
MAFG (untagged)-Human v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) (MAFG), transcript variant 1
CNY 1,200.00
CNY 3,990.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | hMAF |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC118695 sequence for NM_002359 edited (data generated by NextGen Sequencing)
ATGACGACCCCCAATAAAGGAAACAAGGCCTTGAAGGTGAAGCGGGAGCCGGGTGAGAAT GGCACCAGCCTGACGGATGAGGAGCTGGTGACCATGTCGGTGCGGGAGCTGAACCAGCAC CTGCGGGGCCTGTCCAAGGAGGAGATCGTCCAGCTGAAGCAGCGCCGGCGCACGCTCAAG AACCGCGGCTACGCTGCCAGCTGCCGCGTGAAGCGGGTGACGCAGAAGGAGGAGCTGGAG AAGCAGAAGGCGGAGCTGCAGCAGGAGGTGGAGAAGCTGGCCTCAGAGAACGCCAGCATG AAGCTGGAGCTCGACGCGCTGCGCTCCAAGTACGAGGCGCTGCAGACCTTCGCCCGGACG GTGGCCCGCAGCCCCGTGGCGCCAGCCCGGGGCCCCCTTGCCGCCGGCCTGGGGCCCCTC GTCCCAGGCAAGGTGGCCGCCACCAGCGTCATCACAATAGTAAAGTCCAAGACGGATGCC CGATCGTAG Clone variation with respect to NM_002359.3 >OriGene 5' read for NM_002359 unedited
TGTCGGGATTTTGTAAACGACTTATATAGGCGGCCGCGNAATTCGCACCAGCCGGCCTTC CAGTGCGCTCGGCCCGGCCCGCGCAGGCGGCGAGTCCTCCGAGCCCCGGGCCCGGACCCC TCGCGCCGGTCCCTGCCCCGCGCGGCCTCGGAGCGCGCGCGGCCCCGCCCCGCCCCGGCC TCGGCCCGCCGGGCCCGCAGTGTGAGAGCGCCTGCTCGCTGTGCCCCCGGGTTATGACGA CCCCCAATAAAGGAAACAAGGCCTTGAAGGTGAAGCGGGAGCCGGGTGAGAATGGCACCA GCCTGACGGATGAGGAGCTGGTGACCATGTCGGTGCGGGAGCTGAACCAGCACCTGCGGG GCCTGTCCAAGGAGGAGATCGTCCAGCTGAAGCAGCGCCGGCGCACGCTCAAGAACCGCG GCTACGCTGCCAGCTGCCGCGTGAAGCGGGTGACGCAGAAGGAGGAGCTGGAGAAGCAGA AGGCGGAGCTGCAGCAGGAGGTGGAGAAGCTGGCCTCAGAGAACGCCAGCATGAAGCTGG AGCTCGACGCGCTGCGCTCCAAGTACGAGGCGCTGCAGACCTTCGCCCGGACGGTGGCCC GCAGCCCCGTGGCGCCAGCCCGGGGCCCCCTTGCCGCCGGCCTGGGGCCCCTCGTCCCAG GCAAGGTGGCCGCCACCAGCGTCATCACAATAGTAAAGTCCAAGACGGATGCCCGATCGT NAGGACGCGCGTCTGCCCAGGCGGGTCTTTGCGGGGCCACTAGGCACATGGCGAATTTGG CTGCCCTGTCCCTCTGTTTCCCTTCTCTCTCTTTCCTCCCTCTCTTCCCCACCCTTTCTC TCTTTCCTGCCAAGCACAACCTGTACCCCAGGGGCGCCCGGGCTGGAGCCCCTTTGATCT CGTCATTGTCGTCCTGTGTTTTGTATGTTGGGGATGGG >OriGene 3' read for NM_002359 unedited
GCTANATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTAACTAGCAAAGT TTCTATTATACTTTCTTCCCTTTTCCATTCATATGGTCAAATGGTCTTCTTGCTTGTTTT TTTTCTAAAAGACAGTTTTATAAATACTCTGCAGCTCTTTTTTCTTTAACTTTTAAACAT ATAATTAATTTAATAACTTTGTAAAAGGAACTTCTCTCTTTTAAATAAAGGGCTATTTAA CCACCCAAATAGGTCATGTAAACAGTGACACGGGACCCATCGCAGGGCACACTGGACCCA CCCTCACGTTAAGCGCACAACCAGCGATTTGGTCTTGTTCAGTGCAACGGGTCAGGCCTG AGTGCACAGCCCCTGGGCCCAGCTGCACGCCCCCAGCACCACTGGGCCCAGGCTGGTGGT CCACCCATCAGGGCCTTCAAGCCCGCCCTACTCTCAGAGCAGAGCCCATCTCTTCATGCT GGGCTAAGCTGAGCTGCCCCCCTGGGGCTAAAGAGAGTGAATCCTTCCCAGCCCGCGAGC CTGTGGCCACTCGGGAGTGGAGGGAACACTGGGACCCTCACTGCTCGGGGACACGCGAGG CCCAGCGTGCCTGCTCCTTTTCTTTCCCGCAACTTTCTTTATTCCGTTCCCACAGCAACA ACTCTGGACTCCAAGCCTGCATGGCCCCTGGTACAAAAGGGGGTTGGGGCGTACCCCCTC TTCCCCGGCCGATTTTGACCCATTCCCCACCTTTCCAAAAACCCCCCACGGACCATTGAC TGAGTTTCAAATGGGCCCTCACCCCGCGCC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_002359 |
| Insert Size | 1750 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_002359.2, NP_002350.1 |
| RefSeq Size | 5043 bp |
| RefSeq ORF | 489 bp |
| Locus ID | 4097 |
| UniProt ID | O15525 |
| Domains | bZIP_Maf, BRLZ |
| Protein Families | Druggable Genome, Transcription Factors |
| Gene Summary | Globin gene expression is regulated through nuclear factor erythroid-2 (NFE2) elements located in enhancer-like locus control regions positioned many kb upstream of alpha- and beta-gene clusters (summarized by Blank et al., 1997 [PubMed 9166829]). NFE2 DNA-binding activity consists of a heterodimer containing a ubiquitous small Maf protein (MafF, MIM 604877; MafG; or MafK, MIM 600197) and the tissue-restricted protein p45 NFE2 (MIM 601490). Both subunits are members of the activator protein-1-like superfamily of basic leucine zipper (bZIP) proteins (see MIM 165160).[supplied by OMIM, Mar 2010] Transcript Variant: This variant (1) represents the shorter transcript. Both variants 1 and 2 encode the same protein. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Transcription factor nuclear factor erythroid-2 mediates expression of the cytokine interleukin 8, a known predictor of inferior outcome in patients with myeloproliferative neoplasms
,Julius Wehrle, Thalia S. Seeger, Sven Schwemmers, Dietmar Pfeifer, Alla Bulashevska, and Heike L. Pahl,
Haematologica, Jul 2013; 98: 1073 - 1080.
,PubMed ID 23445878
[MafG]
|
|
MPN patients harbor recurrent truncating mutations in transcription factor NF-E2
,Jonas S. Jutzi, Ruzhica Bogeska, Gorica Nikoloski, Corina A. Schmid, Thalia S. Seeger, Frank Stegelmann, Sven Schwemmers, Albert Gründer, Jan C. Peeken, Monika Gothwal, Julius Wehrle, Konrad Aumann, Kamar Hamdi, Christine Dierks, Wei Wang, Konstanze Döhner, Joop H. Jansen, and Heike L. Pahl,
J. Exp. Med., May 2013; 210: 1003 - 1019.
,PubMed ID 23589569
[MAFG]
|
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC221486 | MAFG (Myc-DDK-tagged)-Human v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) (MAFG), transcript variant 1 |
CNY 1,200.00 |
|
| RC221486L1 | Lenti ORF clone of Human v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) (MAFG), transcript variant 1, Myc-DDK-tagged |
CNY 3,600.00 |
|
| RC221486L2 | Lenti ORF clone of Human v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) (MAFG), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC221486L3 | Lenti ORF clone of Human v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) (MAFG), transcript variant 1, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC221486L4 | Lenti ORF clone of Human v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) (MAFG), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RG221486 | MAFG (tGFP-tagged) - Human v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) (MAFG), transcript variant 1 |
CNY 4,370.00 |
