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Neutrophil defensin 4 (DEFA4) (NM_001925) Human Untagged Clone
CAT＃: SC118948
DEFA4 (untagged)-Human defensin, alpha 4, corticostatin (DEFA4)
CNY 1,200.00
CNY 3,990.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | DEF4; HNP-4; HP-4; HP4 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC118948 sequence for NM_001925 edited (data generated by NextGen Sequencing)
ATGAGGATTATCGCCCTCCTCGCTGCTATTCTCTTGGTAGCCCTCCAGGTCCGGGCAGGC CCACTCCAGGCAAGAGGTGATGAGGCTCCAGGCCAGGAGCAGCGTGGGCCAGAAGACCAG GACATATCTATTTCCTTTGCATGGGATAAAAGCTCTGCTCTTCAGGTTTCAGGCTCAACA AGGGGCATGGTCTGCTCTTGCAGATTAGTATTCTGCCGGCGAACAGAACTTCGTGTTGGG AACTGCCTCATTGGCGGTGTGAGTTTCACATACTGCTGCACGCGTGTCGATTAA Clone variation with respect to NM_001925.1 255 t=>c >OriGene 5' read for NM_001925 unedited
TCAGCATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGCTGGAACACAGA CTGCTGTCTGCCCTCTCTGCTCGCCCTGCCTAGCTTGAGGATCTGTCACCCCAGCCATGA GGATTATCGCCCTCCTCGCTGCTATTCTCTTGGTAGCCCTCCAGGTCCGGGCAGGCCCAC TCCAGGCAAGAGGTGATGAGGCTCCAGGCCAGGAGCAGCGTGGGCCAGAAGACCAGGACA TATCTATTTCCTTTGCATGGGATAAAAGCTCTGCTCTTCAGGTTTCAGGCTCAACAAGGG GCATGGTCTGCTCTTGCAGATTAGTATTCTGCCGGCGAACAGAACTTCGTGTTGGGAACT GCCTCATTGGCGGTGTGAGTTTCACATACTGCTGCACGCGTGTCGATTAACATTCTGCTG TCCAAGAGAATGTCATGCTGGGAACGCCATCATCGGTGGTGTTAGCTTCACATGCTTCTG CAGCTGAGCTTGCAGAATAGAGAAAAATGAGCTCATAATTTGCTTTGAGAGCTACAGGAA ATGGTTGTTTCTCCTATACTTTGTCCTTAACATCTTTCTTGATCCTAAATATATATCTCG TAACAAGATGAANNANANAAAANAAAAAAAAAAAAAAAACTCGACTCTAGATTGCGGCCG CGGTCATAGCTGTTTCCTGAACAGATCCCGGGTGGCATCCCTGTGACCCCTCCCCAGTGC CTCTCCTGGCCCTGGAAGTTGCCACTCCAGTGCCCACCAGCCTTGTCCTAATAAAATTAA GTTGCATCATTNTGTCTGACTAGGTGTCCTTCTATAATATATAGGGGTGAGGGGGTGGGG TATTGGGACCAAGGGGCCAGNTGGGAAAAACACCTGTAGGCCTTGCGGTTCTATGGGAAC CAGCTGGATGCAGTGCCCAATCTGGCTCATGCATCTCGCTCCTGGGTCAGCGATCTN >OriGene 3' read for NM_001925 unedited
NGGGCNACNNNGCCCCCTTANTTTGGGCGATTTGNACCGGGCCGCATACTAGATCGAGTN NTTTTTTTTTTAGTTTTTTTTTTTTTTCATCTTGTTACGAGAAATATATTTAGGATCAAG AAAGATGTTAAGGACAAAGTATAGGGAAAAACAACCATTTCCTGTAGCTCTCAAAGCAAA TTATGAGCTCATTTTTCTCTATTCTGCAAGCTCAGCTGCAAAAGCATGTGAAGCTAACAC CACCGATGATGGCGTTCCCAGCATGACATTCTCTTGGACAGCAGAATGTTAATCGACACG CGTGCAGCAGTATGTGAAACTCACACCGCCAATGAGGCAGTTCCCAACACGAAGTTCTGT TCGCCGGCAGAATACTAATCTGCAAGAGCAGACCATGCCCCTTGTTGAGCCTGAAACCTG AAGAGCAGAGCTTTTATCCCATGCAAAGGAAATAGATATGTCCTGGTCTTCTGGCCCACG CTGCTCCTGGCCTGGAGCCTCATCACCTCTTGCCTGAAGTGGGCCTGCCCGCACCTGGAG GGCTACCAAGAGAATAGCAGCGAGGAGGGCGATTATCCTCATGGCTGGGTGACAGATCCT CAAGCTAGGCAGGCCGAGCAGAAAGGCCAAACCGCAGTCCTGTGTTCCAGCTCGTGCCCG AATCCCGGCCGGCCTATGTGAGTCGTATACAAAATTTTGACGGTCACTAACGAGCTTTGT TAAATAGACCTCCACCGTACCGCCTACCGCCATTTTGCGTAACGGGGCGGGGTAATACCA AATTTTGAAAGTCCCGTGATTTTGGTGCCAAACAACTCCCATGCCGAAATGGGGGGAAAC TGGAAACCCCGGGAGTAAACCGTTCCCCGCCCTGGGGGACTGCCAAACCGTTACCCGGGG AAAGCCAGATAAAACCTAAATTCCTGCCAAATGGAAACCCCTAAGCCATTTCTGGGAATA AGCCAGGGGCATTTACGGTTTGAGCAAAAGGGGGGCCCTG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001925 |
| Insert Size | 600 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001925.1, NP_001916.1 |
| RefSeq Size | 542 bp |
| RefSeq ORF | 294 bp |
| Locus ID | 1669 |
| UniProt ID | P12838 |
| Domains | Defensin_propep, DEFSN, defensins |
| Protein Families | Secreted Protein |
| Gene Summary | Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. The protein encoded by this gene, defensin, alpha 4, is found in the neutrophils; it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production. [provided by RefSeq, Oct 2014] |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC213236 | DEFA4 (Myc-DDK-tagged)-Human defensin, alpha 4, corticostatin (DEFA4) |
CNY 1,200.00 |
|
| RC213236L3 | Lenti-ORF clone of DEFA4 (Myc-DDK-tagged)-Human defensin, alpha 4, corticostatin (DEFA4) |
CNY 5,890.00 |
|
| RC213236L4 | Lenti-ORF clone of DEFA4 (mGFP-tagged)-Human defensin, alpha 4, corticostatin (DEFA4) |
CNY 5,890.00 |
|
| RG213236 | DEFA4 (tGFP-tagged) - Human defensin, alpha 4, corticostatin (DEFA4) |
CNY 4,370.00 |
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