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GTF2H4 (NM_001517) Human Untagged Clone
CAT＃: SC119182
GTF2H4 (untagged)-Human general transcription factor IIH, polypeptide 4, 52kDa (GTF2H4)
CNY 3,656.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | P52; TFB2; TFIIH |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_001517, the custom clone sequence may differ by one or more nucleotides
ATGGAGAGCACCCCTTCAAGGGGACTGAACCGAGTACACCTACAATGCAGGAATCTGCAGGAATTCTTAG GGGGCCTGAGCCCTGGGGTATTGGACCGATTGTATGGGCACCCTGCCACATGTCTGGCTGTCTTCAGGGA GCTCCCATCCTTGGCTAAGAACTGGGTGATGCGGATGCTCTTTCTGGAGCAGCCTTTGCCACAGGCTGCT GTAGCTCTGTGGGTAAAGAAGGAATTCAGCAAGGCTCAGGAGGAAAGTACAGGGCTGCTGAGCGGCCTCC GGATCTGGCACACACAGCTGCTCCCAGGCGGGCTCCAGGGCCTCATCCTCAACCCCATTTTCCGCCAGAA CCTCCGCATTGCCCTTCTGGGTGGGGGGAAGGCCTGGTCTGATGACACAAGTCAGCTGGGACCAGACAAG CATGCCCGGGACGTTCCCTCCCTTGACAAGTACGCCGAGGAGCGATGGGAGGTGGTCTTGCACTTCATGG TGGGCTCCCCCAGTGCAGCTGTCAGCCAGGACTTGGCTCAGCTCCTCAGCCAGGCTGGGCTCATGAAGAG TACTGAACCTGGAGAGCCGCCCTGCATTACTTCCGCTGGCTTCCAGTTCCTGTTGCTGGACACCCCGGCT CAGCTCTGGTACTTTATGTTGCAGTATTTGCAGACAGCCCAGAGCCGGGGCATGGACCTGGTAGAGATTC TCTCCTTCCTCTTCCAGCTCAGCTTCTCTACTCTGGGCAAGGATTACTCTGTGGAAGGTATGAGTGATTC TCTGTTGAACTTCCTGCAACATCTGCGTGAGTTTGGGCTTGTTTTCCAGAGGAAGAGGAAATCTCGGCGT TACTACCCCACACGCCTGGCCATCAATCTCTCATCAGGTGTCTCTGGAGCTGGGGGCACTGTGCATCAGC CAGGTTTCATTGTCGTGGAAACCAATTACCGACTGTATGCCTACACGGAGTCGGAGCTGCAGATTGCCCT CATTGCCCTCTTCTCTGAGATGCTCTATCGGTTCCCCAACATGGTGGTGGCGCAGGTGACCCGGGAGAGT GTGCAGCAGGCAATCGCCAGTGGCATCACAGCCCAGCAGATAATCCATTTCCTAAGGACAAGAGCCCACC CAGTGATGCTCAAACAGACACCTGTGCTGCCCCCCACCATCACCGACCAGATCCGGCTCTGGGAGCTGGA AAGGGACAGACTCCGGTTCACTGAGGGTGTCCTGTATAACCAGTTCCTGTCGCAAGTGGACTTTGAGCTG CTGCTGGCCCACGCGCGGGAGCTGGGCGTGCTCGTGTTCGAGAACTCGGCCAAGCGGCTCATGGTGGTGA CCCCGGCCGGGCACAGCGACGTCAAGCGCTTTTGGAAGCGGCAGAAACATAGCTCCTGA >OriGene 5' read for NM_001517 unedited
CGGCATTTGTATACGACTCCTATAGGCGGCCGCGNAATTCGCACGAGGCTGAATTCTCCA TTCTGGGCTCTTGCCTGTGAAATCTTTCTTTGCTTTCCCCATCTTTTCCTCGCATTTTTT CACCATCTTTCCCTCAATCTCCAGGAGCCAATGCGAGACTTTGGCTCCGATTAAGCGACG GCCCGAGACTCGGGGTGCGCGAGGAGGATCGACAGAGTGGTGATGGAGAGCACCCCTTCA AGGGGACTGAACCGAGTACACCTACAATGCAGGAATCTGCAGGAATTCTTAGGGGGCCTG AGCCCTGGGGTATTGGACCGATTGTATGGGCACCCTGCCACATGTCTGGCTGTCTTCAGG GAGCTCCCATCCTTGGCTAAGAACTGGGTGATGCGGATGCTCTTTCTGGAGCAGCCTTTG CCACAGGCTGCTGTAGCTCTGTGGGTAAAGAAGGAATTCAGCAAGGCTCAGGAGGAAAGT ACAGGGCTGCTGAGCGGCCTCCGGATCTGGCACACACAGCTGCTCCCAGGCGGGCTCCAG GGCCTCATCCTCAACCCCATTTTCCGCCAGAACCTCCGCATTGCCCTTCTGGGTGGGGGG AAGGCCTGGTCTGATGACACAAGTCAGCTGGGACCAGACAAGCATGCCCGGGACGTTCCC TCCCTTGACAAGTACGCCGAGGAGCGATGGGAGGTGGTCTTGCACTTCATGGTGGGCTCC CCCAGTGCAGCTGTCAGCCAGGACTTGGCTCAGCTCCTCAGCCAGGCTGGGCTCATGAAG AGTACTGAACCTGGAGAGCCGNCCTGCATTACTTCCGCTGGCTTCCAGTTCCTGTTGCTG GACACCCCNGCTCAGCTCTGGTACTTTATGNTGCAGTATTTGCAGACAGCCCANCCCGGG CATGGACCCTGGTANAGATCTCTCCTTCCTCCTTCAGCTCAGCTTN >OriGene 3' read for NM_001517 unedited
GACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTGCTAGCTATCATAA CTTTATTAAACAAGAAAAGCCCTGACGCGTAAATAAAAAACACCTGAGTTCTGATGCCCC GCCCCGCCCAGTCCCGCCCGCCGAGGTCCGTGTCCAAGTCCCGCGCTCTCAGGAGCTATG TTTCTGCCGCTTCCAAAAGCGCTTGACGTCGCTGTGCCCGGCCGGGGTCACCACCATGAG CCGCTTGGCCGAGTTCTCGAACACGAGCACGCCCAGCTCCCGCGCGTGGGCCAGCAGCAG CTCAAAGTCCACTTGCGACAGGAACTGGTTATACAGGACACCCTCAGTGAACCGGAGTCT GTCCCTTTCCAGCTCCCAGAGCCGGATCTGGTCGGTGATGGTGGGGGGCAGCACAGGTGT CTGTTTGAGCATCACTGGGTGGGCTCTTGTCCTTAGGAAATGGATTATCTGCTGGGCTGT GATGCCACTGGCGATTGCCTGCTGCACACTCTCCCGGGTCACCTGCGCCACCACCATGTT GGGGAACCGATAGAGCATCTCAGAGAAGAGGGCAATGAGGGCAATCTGCAGCTCCGACTC TGAGCCAGGGATAGAAAGAGGATGAGGAGGCCACCCCCACACCCAGACTCCCTCAAGCCC TTCTTTCAAGTGTCATGAGAAATGTCAGAGAGCTCTGTAGACTGCCAGGTAAACACGAAC ATAAACTGGCATTCCCTCACCCCCAACCTTCTCTTCCAGGGGCCCNTCTGTCCCGCCTCA CCCGTGTAGGCATACAGTCGGGTATTGGGTTTCCACGACATGAAACCTGGCTGATGCACA GTGCCCCCAGCTCCAGAGACACCTGATGAGAGATTGATGGCCANGCGTGTGGNGTAGTAA CGCCGAGATTTCCTCTGAAANGATAAAAGGCAGATGCCTGNCTCANAAGCACTGGCTTAA TCTNCTGCTGAATATCAGACCCTCCAGAGCAGACCTCACCNCACTCT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001517 |
| Insert Size | 2100 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001517.4, NP_001508.1 |
| RefSeq Size | 1736 bp |
| RefSeq ORF | 1389 bp |
| Locus ID | 2968 |
| UniProt ID | Q92759 |
| Domains | Tfb2 |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | Basal transcription factors, Nucleotide excision repair |
| Gene Summary | Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription.[UniProtKB/Swiss-Prot Function] |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202555 | GTF2H4 (Myc-DDK-tagged)-Human general transcription factor IIH, polypeptide 4, 52kDa (GTF2H4) |
CNY 3,656.00 |
|
| RC202555L1 | Lenti ORF clone of Human general transcription factor IIH, polypeptide 4, 52kDa (GTF2H4), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC202555L2 | Lenti ORF clone of Human general transcription factor IIH, polypeptide 4, 52kDa (GTF2H4), mGFP tagged |
CNY 5,890.00 |
|
| RC202555L3 | Lenti ORF clone of Human general transcription factor IIH, polypeptide 4, 52kDa (GTF2H4), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC202555L4 | Lenti ORF clone of Human general transcription factor IIH, polypeptide 4, 52kDa (GTF2H4), mGFP tagged |
CNY 5,890.00 |
|
| RG202555 | GTF2H4 (tGFP-tagged) - Human general transcription factor IIH, polypeptide 4, 52kDa (GTF2H4) |
CNY 4,370.00 |
