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LARGE (LARGE1) (NM_133642) Human Untagged Clone
CAT＃: SC120425
LARGE (untagged)-Human like-glycosyltransferase (LARGE), transcript variant 2
CNY 5,544.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | LARGE; MDC1D; MDDGA6; MDDGB6 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>NCBI ORF sequence for NM_133642, the custom clone sequence may differ by one or more nucleotides
ATGCTGGGAATCTGCAGGGGGAGACGGAAATTCTTGGCTGCCTCGTTGAGTCTTCTCTGCATCCCAGCCA TCACCTGGATTTACCTGTTTTCTGGGAGCTTCGAAGATGGAAAGCCCGTGTCTCTGTCACCGCTGGAGTC CCAGGCACACAGCCCCAGGTACACGGCCTCCAGCCAGCGGGAGCGCGAGAGCCTGGAGGTGCGCATGCGC GAGGTGGAGGAGGAGAACCGCGCCCTCCGCAGGCAGCTCAGCCTGGCCCAGGGCCGAGCCCCATCCCATC GCCGAGGCAACCACTCCAAGACCTACTCCATGGAGGAGGGCACTGGAGACAGCGAGAACCTTCGGGCTGG CATCGTGGCAGGCAACAGCTCCGAGTGTGGGCAGCAGCCGGTCGTGGAGAAATGCGAGACAATCCACGTT GCTATTGTCTGCGCCGGATACAATGCCAGCCGGGATGTCGTCACCCTGGTCAAATCCGTCCTGTTCCATA GACGGAACCCTCTGCACTTCCACCTTATTGCTGACTCCATTGCGGAGCAGATCCTGGCCACGCTCTTCCA GACCTGGATGGTGCCCGCTGTGCGTGTGGACTTCTACAATGCAGACGAGCTCAAGTCTGAAGTTTCCTGG ATCCCCAATAAACATTACTCTGGGATTTATGGTCTGATGAAGCTTGTCCTGACCAAGACTCTTCCTGCCA ACCTGGAGAGAGTCATCGTCCTTGACACGGATATCACCTTTGCCACTGACATTGCAGAGCTGTGGGCTGT GTTCCACAAGTTCAAAGGTCAGCAAGTCCTGGGCTTGGTGGAGAACCAGAGTGACTGGTACCTTGGAAAC CTGTGGAAAAATCACCGCCCATGGCCAGCCCTTGGAAGAGGCTACAACACAGGGGTGATCCTGTTACTTC TGGATAAGCTGCGGAAGATGAAATGGGAGCAGATGTGGAGGCTGACCGCAGAGAGGGAGCTCATGGGCAT GCTCTCTACATCCTTAGCTGACCAGGATATTTTCAATGCCGTCATCAAACAAAACCCCTTCCTTGTGTAC CAGCTCCCCTGCTTCTGGAATGTGCAGCTGTCAGACCACACCCGCTCCGAGCAGTGCTACAGAGACGTGT CTGATCTAAAGGTCATTCACTGGAACTCCCCCAAGAAGCTCCGGGTGAAGAACAAGCATGTGGAGTTTTT TCGCAACCTCTACCTGACCTTCCTGGAGTATGACGGCAATCTTCTGAGGCGGGAACTGTTTGGCTGCCCC AGTGAGGCTGATGTCAACAGTGAAAACCTCCAGAAGCAGCTGTCTGAGCTGGACGAGGACGACCTGTGCT ATGAGTTCCGGCGAGAGCGCTTCACTGTCCACCGCACCCACCTGTACTTCCTGCACTACGAGTATGAGCC TGCAGCAGACAGCACGGACGTCACCCTGGTCGCTCAGCTGTCCATGGACAGGCTCCAGATGCTGGAGGCC ATCTGCAAGCACTGGGAGGGGCCCATCAGCCTGGCCCTCTACCTGTCAGACGCCGAGGCCCAGCAGTTCC TCCGCTACGCACAGGGCTCTGAGGTGCTTATGAGCCGCCACAACGTGGGCTACCACATCGTGTACAAGGA GGGCCAGTTCTACCCCGTGAACCTGCTGCGCAACGTGGCCATGAAGCACATCAGCACTCCCTACATGTTC CTGTCTGACATTGACTTCCTGCCCATGTATGGGCTCTATGAGTACCTCAGGAAGTCTGTCATCCAGCTCG ATCTTGCCAACACCAAGAAAGCAATGATTGTCCCCGCGTTCGAGACACTGCGCTACCGGCTGTCCTTCCC CAAGTCAAAAGCGGAGTTGCTGTCAATGCTGGACATGGGGACCCTCTTCACATTCAGGTACCACGTCTGG ACGAAAGGCCACGCACCCACAAACTTCGCCAAGTGGCGGACCGCCACCACGCCTTACCGGGTTGAGTGGG AGGCCGATTTTGAGCCGTATGTTGTTGTGAGACGTGACTGCCCGGAGTACGACCGGAGGTTTGTAGGCTT TGGCTGGAACAAAGTGGCTCATATCATGGAGCTGGATGTGCAGGAGTATGAGTTCATTGTGCTGCCCAAC GCCTACATGATCCACATGCCTCATGCCCCCAGCTTCGACATTACCAAGTTCCGTTCCAACAAGCAATACC GCATCTGTCTCAAAACCCTCAAGGAAGAGTTTCAGCAGGACATGTCCCGCCGCTACGGCTTTGCTGCCCT GAAATATCTCACAGCCGAGAACAACAGCTAG >OriGene 5' read for NM_133642 unedited
ATTAGGTATACGAACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCAGCCCCCCCCG CGCCGCCGCGCTCGGCGCCCGGCCCGGCCAGTCTGCTCCTGCCCCGCCGCCGCGCCGGAG CCCGGGCGCCCGAAGCTGGGGGCGCGGCCGCGCTCGTCTCGCCGGGCTGTTCGCGGGCAG GCCCTGCCCTGAAGGGACGAATCGGCTTGGAGCGCGGGAGGTGGAGTCGGCCCCGGCGGT CGCTCCCTGGACCCAACCCGAGGCTGACCCAGGCCCCTGCCCATGCGGGGCGCCCCTGTC TCGGAAGAGTCCCCCGGGCCGGGAGCAGCTCCAGGCAGCGGCCCCGGAGGAAGAGGAAGA AGGGACAGTGCTCAGCTTGGGGGACCCGGACCCTCGCCGCGGCATTTGGAGCCGGGGGCA GTCCCGAACTCTGTGCTTGGCACCGCCGCTCCGAGTAGGGCAGCGCCTGCCGGGACTCTG ACCCGGACCCCCTGCGCCTCGTAGGCGGCGGCGCCGCCGCGCCACCCTGTTCTTCCGTGT CTCCCTCTGCCTGGCGGCAGTCACGGCCAAGAACCTACATTAAGAAACGCATTCAGATGC ATCAGCCGTTTGTAAAGCACCTGTCGTGAGCCAGAGAGTATTATGAGGGAGGCCGAGGAC TTCATGCTCCGGACAGAGAAACGGCGCTGGGATTANGGATTGCCACTTCTGAGAGGATGC TGGGAATCTGCAGGNGGAGACGGANATTCTTGGCTGCCTCGTTGAGTCTTCTCTGCATCC CAGCCATCACCTGGGATTACCTGTTTTCTGGGAGCTTCGAAGATGAAAGCCCGTGTCTCT GTCACCGCTGGAGTCCCCAGCCACAGGCCCAGTTACACGGCCTCCAGCCAGCGGGAGCGC GAGAGCCTGTAGTGCGCATGCCCCAGTTGGAGAGAAGACCGCGCCTCCGCAGCAGGTAAC CTGTCCAGGCCGACCCCATCT >OriGene 3' read for NM_133642 unedited
ATCGGAGGTAAAAAAACCCCCGTCGCTTTCGCTGGTCACATCTGCACTCATACAAACAGC CCTTTGTAGGTAGGGCATTAACTCTTGTTCTCATCAATGTAAACACAATATTAATATTGA AGATTAAAGAAAATGGGTAAAAAGTCCAGTGTCTCCTCAATCTGTGTGAAGGTGAAGGTG GTTGCCTACCCTTGGACAGGTCCCAAAGGGAGACTGTTGTTGTCACCTCTTCCCATCCAC AGTGAAGCAGGCAAGAACCAGAGGAACCCAATCACTTTCTTCCTGTAGGTCTCCAGATGG ATACGTGAATCTTCAGAACTGGGCTTTCATGAATTATGAAAGTTCTTCGAAAGGCCTGAG AGGTTCGTACCTTGTGTGTGCACTGAAGTAGTTCCTTCACAGCCCTTTCCCATGAATCAG TCCCTGCCAATAGAAAATGTGACCGGTGTAAAACAGCCATCCCCTCGTAATTCCGCAGTC CCCATCGCTCTAGCCCCTGGATTCTGGAGAGTCGGGAGTTCATAGTCACGGTAGCCTCGG TGATCCTCCCTGACGGAAGCCTGCCCTGCTCAATTATCGGCCGAAGATGCCTTGACCTCC TTTCCTGAGCCACTGCTTGCTACAGGGGTGCTGCGCCCACGCAGCCTGACTCTTCCTTCT ATCGCCTCACAGGCACAGATCTCCCTCTCTCCGTTTTGTCACCCCCTATCGTTACCACAA CCTCCCTGCCATATCCTTTCTACTCTGGTGCTGCCTTTGCGGATATTGAAACCCCCTCCT CCCCCCCTTCCGCTCCCTCTGCGTCCACCGGCTCCTCTTGCGGTTTCTCCTCATGTTTGT CTAACCTCTTCGGCATGTCCTCCCTTATTATATCCCCGCTTCCATAGTGGGGCTCACGCG TTACCTCTCCCCCTCGCTAGGCCATTTTCCGCTTCATCTCCATGAAAAAAAAAC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_133642 |
| Insert Size | 3750 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_133642.2, NP_598397.1 |
| RefSeq Size | 4131 bp |
| RefSeq ORF | 2271 bp |
| Locus ID | 9215 |
| UniProt ID | O95461 |
| Domains | Glyco_transf_8 |
| Protein Families | Druggable Genome, Transmembrane |
| Gene Summary | This gene encodes a member of the N-acetylglucosaminyltransferase gene family. It encodes a glycosyltransferase which participates in glycosylation of alpha-dystroglycan, and may carry out the synthesis of glycoprotein and glycosphingolipid sugar chains. It may also be involved in the addition of a repeated disaccharide unit. The protein encoded by this gene is the glycotransferase that adds the final xylose and glucuronic acid to alpha-dystroglycan and thereby allows alpha-dystroglycan to bind ligands including laminin 211 and neurexin. Mutations in this gene cause several forms of congenital muscular dystrophy characterized by cognitive disability and abnormal glycosylation of alpha-dystroglycan. Alternative splicing of this gene results in multiple transcript variants that encode the same protein. [provided by RefSeq, May 2018] Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC223788 | LARGE (Myc-DDK-tagged)-Human like-glycosyltransferase (LARGE), transcript variant 2 |
CNY 5,536.00 |
|
| RC223788L3 | Lenti ORF clone of Human like-glycosyltransferase (LARGE), transcript variant 2, Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC223788L4 | Lenti ORF clone of Human like-glycosyltransferase (LARGE), transcript variant 2, mGFP tagged |
CNY 5,890.00 |
|
| RG223788 | LARGE (tGFP-tagged) - Human like-glycosyltransferase (LARGE), transcript variant 2 |
CNY 7,136.00 |
