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CACNA2D3 (NM_018398) Human Untagged Clone
CAT＃: SC121942
CACNA2D3 (untagged)-Human calcium channel, voltage-dependent, alpha 2/delta subunit 3 (CACNA2D3)
CNY 11,408.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HSA272268 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_018398 edited
GGCAGGCGGGGCGGCGCGGAGCGGAGCAGGCAGCCCCGCGCGCTCGCCCACCGCCCGCTC CGCGCAGCTCCCCGCGGCCGCTCTCGTCGCCGCCGCAGCGGGCGCGTCGGAGGGAGCCCA GCATGGCCGGGCCGGGCTCGCCGCGCCGCGCGTCCCGGGGGGCCTCGGCGCTTCTCGCTG CCGCGCTTCTCTACGCCGCGCTGGGGGACGTGGTGCGCTCGGAGCAGCAGATACCGCTCT CCGTGGTGAAGCTCTGGGCCTCGGCTTTTGGTGGGGAGATAAAATCCATTGCTGCTAAGT ACTCCGGTTCCCAGCTTCTGCAAAAGAAATACAAAGAGTATGAGAAAGACGTTGCCATAG AAGAAATTGATGGCCTCCAACTGGTAAAGAAGCTGGCAAAGAACATGGAAGAGATGTTTC ACAAGAAGTCTGAGGCCGTCAGGCGTCTGGTGGAGGCTGCAGAAGAAGCACACCTGAAAC ATGAATTTGATGCAGACTTACAGTATGAATACTTCAATGCTGTGCTGATAAATGAAAGGG ACAAAGACGGGAATTTTTTGGAGCTGGGAAAGGAATTCATCTTAGCCCCAAATGACCATT TTAATAATTTGCCTGTGAACATCAGTCTAAGTGACGTCCAAGTACCAACGAACATGTACA ACAAAGACCCTGCAATTGTCAATGGGGTTTATTGGTCTGAATCTCTAAACAAAGTTTTTG TAGATAACTTTGACCGTGACCCATCTCTCATATGGCAGTACTTTGGAAGTGCAAAGGGCT TTTTTAGGCAGTATCCGGGGATTAAATGGGAACCAGATGAGAATGGAGTCATTGCCTTCG ACTGCAGGAACCGAAAATGGTACATCCAGGCAGCAACTTCTCCGAAAGACGTGGTCATTT TAGTTGACGTCAGTGGCAGCATGAAAGGACTCCGTCTGACTATCGCGAAGCAAACAGTCT CATCCATTTTGGATACACTTGGGGATGATGACTTCTTCAACATAATTGCTTATAATGAGG AGCTTCACTATGTGGAACCTTGCCTGAATGGAACTTTGGTGCAAGCCGACAGGACAAACA AAGAGCACTTCAGGGAGCATCTGGACAAACTTTTCGCCAAAGGAATTGGAATGTTGGATA TAGCTCTGAATGAGGCCTTCAACATTCTGAGTGATTTCAACCACACGGGACAAGGAAGTA TCTGCAGTCAGGCCATCATGCTCATAACTGATGGGGCGGTGGACACCTATGATACAATCT TTGCAAAATACAATTGGCCAGATCGAAAGGTTCGCATCTTCACATACCTCATTGGACGAG AGGCTGCGTTTGCAGACAATCTAAAGTGGATGGCCTGTGCCAACAAAGGATTTTTTACCC AGATCTCCACCTTGGCTGATGTGCAGGAGAATGTCATGGAATACCTTCACGTGCTTAGCC GGCCCAAAGTCATCGACCAGGAGCATGATGTGGTGTGGACCGAAGCTTACATTGACAGCA CTCTCCCTCAGGCACAAAAGCTGACTGATGATCAGGGCCCCGTCCTGATGACCACTGTAG CCATGCCTGTGTTTAGTAAGCAGAACGAAACCAGATCGAAGGGCATTCTTCTGGGAGTGG TTGGCACAGATGTCCCAGTGAAAGAACTTCTGAAGACCATCCCCAAATACAAGTTAGGGA TTCACGGTTATGCCTTTGCAATCACAAATAATGGGTATATCCTGACGCATCCGGAACTCA GGCTGCTGTACGAAGAAGGAAAAAAGCGAAGGAAACCTAACTATAGTAGCGTTGACCTCT CTGAGGTGGAGTGGGAAGACCGAGATGACGTGTTGAGAAATGCTATGGTGAATCGAAAGA CGGGGAAGTTTTCCATGGAGGTGAAGAAGACAGTGGACAAAGGGAAACGGGTTTTGGTGA TGACAAATGACTACTATTATACAGACATCAAGGGTACTCCTTTCAGTTTAGGTGTGGCGC TTTCCAGAGGTCATGGGAAATATTTCTTCCGAGGGAATGTAACCATCGAAGAAGGCCTGC ATGACTTAGAACATCCCGATGTGTCCTTGGCAGATGAATGGTCCTACTGCAACACTGACC TACACCCTGAGCACCGCCATCTGTCTCAGTTAGAAGCGATTAAGCTCTACCTAAAAGGCA AAGAACCTCTGCTCCAGTGTGATAAAGAATTGATCCAAGAAGTCCTTTTTGACGCGGTGG TGAGTGCCCCCATTGAAGCGTATTGGACCAGCCTGGCCCTCAACAAATCTGAAAATTCTG ACAAGGGCGTGGAGGTTGCCTTCCTCGGCACTCGCACGGGCCTCTCCAGAATCAACCTGT TTGTCGGGGCTGAGCAGCTCACCAATCAGGACTTCCTGAAAGCTGGCGACAAGGAGAACA TTTTTAACGCAGACCATTTCCCTCTCTGGTACCGAAGAGCCGCTGAGCAGATTCCAGGGA GCTTCGTCTACTCGATCCCATTCAGCACTGGACCAGTCAATAAAAGCAATGTGGTGACAG CAAGTACATCCATCCAGCTCCTGGATGAACGGAAATCTCCTGTGGTGGCAGCTGTAGGCA TTCAGATGAAACTTGAATTTTTCCAAAGGAAGTTCTGGACTGCCAGCAGACAGTGTGCTT CCCTGGATGGCAAATGCTCCATCAGCTGTGATGATGAGACTGTGAATTGTTACCTCATAG ACAATAATGGATTTATTTTGGTGTCTGAAGACTACACACAGACTGGAGACTTTTTTGGTG AGATCGAGGGAGCTGTGATGAACAAATTGCTAACAATGGGCTCCTTTAAAAGAATTACCC TTTATGACTACCAAGCCATGTGTAGAGCCAACAAGGAAAGCAGCGATGGCGCCCATGGCC TCCTGGATCCTTATAATGCCTTCCTCTCTGCAGTAAAATGGATCATGACAGAACTTGTCT TGTTCCTGGTGGAATTTAACCTCTGCAGTTGGTGGCACTCCGATATGACAGCTAAAGCCC AGAAATTGAAACAGACCCTGGAGCCTTGTGATACTGAATATCCAGCATTCGTCTCTGAGC GCACCATCAAGGAGACTACAGGGAATATTGCTTGTGAAGACTGCTCCAAGTCCTTTGTCA TCCAGCAAATCCCAAGCAGCAACCTGTTCATGGTGGTGGTGGACAGCAGCTGCCTCTGTG AATCTGTGGCCCCCATCACCATGGCACCCATTGAAATCAGGTATAATGAATCCCTTAAGT GTGAACGTCTAAAGGCCCAGAAGATCAGAAGGCGCCCAGAATCTTGTCATGGCTTCCATC CTGAGGAGAATGCAAGGGAGTGTGGGGGTGCGCCGAGTCTCCAAGCCCAGACAGTCCTCC TTCTGCTCCCTCTGCTTTTGATGCTCTTCTCAAGGTGACACTGACTGAGATGTTCTCTTA CTGACTGAGATGTTCTCTTGGCATGCTAAATCATGGATAAACTGTGAACCAAAATATGGT GCAACATACGAGACATGAATATAGTCCAACCATCAGCATCTCATCATGATTTTAAACTGT GCGTGATATAAACTCTTAAAGATATGTTGACAAAAAGTTATCTATCATCTTTTTACTTTG CCAGTCATGCAAATGTGAGTTTGCCACATGATAATCACCCTTCATCAGAAATGGGACCGC AAGTGGTAGGCAGTGTCCCTTCTGCTTGAAACCTATTGAAACCAATTTAAAACTGTGTAC TTTTTAAATAAAGTATATTAAAATCATAAAAAAAAAAAAAAAA >OriGene 5' read for NM_018398 unedited
ATTCGGCACGAGGGGCAGGCGGGGCGGCGCGGAGCAGGAGCAGCAGCCCCGCGCGCTCGC CCACCGCCCGCTCCGCGCAGCTCCCCGCGGCCGCTCTCGTCGCCGCCGCAGCGGGCGCGT CGGAGGGAGCCCAGCATGGCCGGGCCGGGCTCGCCGCGCCGCGCGTCCCGGGGGGCCTCG GCGCTTCTCGCTGCCGCGCTTCTCTACGCCGCGCTGGGGGACGTGGTGCGCTCGGAGCAG CAGATACCGCTCTCCGTGGTGAAGCTCTGGGCCTCGGCTTTTGGTGGGGAGATAAAATCC ATTGCTGCTAAGTACTCCGGTTCCCAGCTTCTGCAAAAGAAATACAAAGAGTATGAGAAA GACGTTGCCATAGAAGAAATTGATGGCCTCCAACTGGTAAAGAAGCTGGCAAAGAACATG GAAGAGATGTTTCACAAGAAGTCTGAGGCCGTCAGGCGTCTGGTGGAGGCTGCAGAAGAA GCACACCTGAAACATGAATTTGATGCAGACTTACAGTATGAATACTTCAATGCTGTGCTG ATAAATGAAAGGGACAAAGACGGGAATTTTTTGGAGCTGGGAAAGGAATTCATCTTAGCC CCAAATGACCATTNTAATAATTTGCCTGTGAACATCAGTCTAAGTGACGTCCAAGTACCA ACGAACATGTACAACAAAGACCCTGCAATTGTCAATGGGGTTTATTGGTCTGAATCTCTA AACAAGTTTTTGTAGATAACTTTGACCGTGACCCATCTCTCATATGGCAGTACTTTTGGA GTGCANAGGGCTTTTTTTAGCAGTATCCGGGGATTAATGGGGACCAGATGAGNATGGAGT CATTGCCTTCGACTGCAGGAACCGAAATGGTACATNCAGGCAGNAACTTTTCGAAAGACG GG >OriGene 3' read for NM_018398 unedited
TCCCCCCCAATGACTATGTACCGCGGCCCGTATACTATGATCGATTTTCTTTTTTTTTTT TTTTTATGATTTTAATATACTTTATTTAAAAATACACAGTTTTAAATTGGTTTCAATAGG TTTCAAGCAGAAGGGACACTGCCTACCACTTGCGGTCCCATTTCTGATGAAGGGTGATTA TCATGTGGCAAACTCACATTTGCATGACTGGCAAAGTTAAAAGATGATAGATAACTTTTT GTCAACATATCTTTAAGAGTTTATATCACGCACAGTTTAAAATCATGATGAGATGCTGAT GGTTGGACTATATTCATGTCTCGTATGTTGCACCATATTTTGGTTCACAGTTTATCCATG ATTTAGCATGCCAAGAGAACATCTCAGTCAGTAAGAGAACATCTCAGTCAGTGTCACCTT GAGAAGAGCATCAAAAGCAGAGGGAGCAGAAGGAGGACTGTCTGGGCTTGGAGACTCGGC GCACCCCCACACTCCCTTGCATTCTCCTCAGGATGGAAGCCATGACAAGATTCTGGGCGC CTTCTGATCTTCTGGGCCTTTAGACGTTCACACTTAAGGGATTCATTATACCTGATTTCA ATGGGTGCCATGGTGATGGGGGCCACAGATTCCCAGAGGCCGCTGCTGTCCACCACCACC ATGAACAGGTTGCTGCCTTGGGATTGGCTGGATGACAAAGGACTTGGAACAATCTTTACA AACCATATTCCCGGGAGTTCCCTTTGAGGTGCCCTCACAAACCAATGGCTGGATATTTAA GAACACAAGGCCTCCAGGGTTCTGTTTCAACTTTCTGGGGCTTTACCTGGCCAATCGGGC GTGGCCCCCCAC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_018398 |
| Insert Size | 3800 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_018398.2, NP_060868.2 |
| RefSeq Size | 3689 bp |
| RefSeq ORF | 3276 bp |
| Locus ID | 55799 |
| UniProt ID | Q8IZS8 |
| Domains | VWA, Cache |
| Protein Families | Druggable Genome, Ion Channels: Other |
| Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC), Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy (HCM), MAPK signaling pathway |
| Gene Summary | This gene encodes a member of the alpha-2/delta subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Various versions of each of these subunits exist, either expressed from similar genes or the result of alternative splicing. Research on a highly similar protein in rabbit suggests the protein described in this record is cleaved into alpha-2 and delta subunits. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. [provided by RefSeq, Jul 2008] |
Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC222306 | CACNA2D3 (Myc-DDK-tagged)-Human calcium channel, voltage-dependent, alpha 2/delta subunit 3 (CACNA2D3) |
CNY 11,392.00 |
|
| RC222306L1 | Lenti ORF clone of Human calcium channel, voltage-dependent, alpha 2/delta subunit 3 (CACNA2D3), Myc-DDK-tagged |
CNY 13,792.00 |
|
| RC222306L2 | Lenti ORF clone of Human calcium channel, voltage-dependent, alpha 2/delta subunit 3 (CACNA2D3), mGFP tagged |
CNY 12,830.00 |
|
| RC222306L3 | Lenti ORF clone of Human calcium channel, voltage-dependent, alpha 2/delta subunit 3 (CACNA2D3), Myc-DDK-tagged |
CNY 12,830.00 |
|
| RC222306L4 | Lenti ORF clone of Human calcium channel, voltage-dependent, alpha 2/delta subunit 3 (CACNA2D3), mGFP tagged |
CNY 12,830.00 |
|
| RG222306 | CACNA2D3 (tGFP-tagged) - Human calcium channel, voltage-dependent, alpha 2/delta subunit 3 (CACNA2D3) |
CNY 12,992.00 |
|
| SC318491 | CACNA2D3 (untagged)-Human calcium channel, voltage-dependent, alpha 2/delta subunit 3 (CACNA2D3) |
CNY 10,450.00 |
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