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Neuroglobin (NGB) (NM_021257) Human Untagged Clone
CAT＃: SC122910
NGB (untagged)-Human neuroglobin (NGB)
CNY 1,200.00
CNY 2,950.00
| Cited in 5 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_021257 edited
CGGAGGAGATGGCGCGGCACGTGCGGTGACGGCACCCGAGCCCTGAGGGTCCCAGCCCCG CGCTCCGCGTCCCCGGGACAGCATGGAGCGCCCGGAGCCCGAGCTGATCCGGCAGAGCTG GCGGGCAGTGAGCCGCAGCCCGCTGGAGCACGGCACCGTCCTGTTTGCCAGGCTGTTTGC CCTGGAGCCTGACCTGCTGCCCCTCTTCCAGTACAACTGCCGCCAGTTCTCCAGCCCAGA GGACTGTCTCTCCTCGCCTGAGTTCCTGGACCACATCAGGAAGGTGATGCTCGTGATTGA TGCTGCAGTGACCAATGTGGAAGACCTGTCCTCACTGGAGGAGTACCTTGCCAGCCTGGG CAGGAAGCACCGGGCAGTGGGTGTGAAGCTCAGCTCCTTCTCGACAGTGGGTGAGTCTCT GCTCTACATGCTGGAGAAGTGTCTGGGCCCTGCCTTCACACCAGCCACACGGGCTGCCTG GAGCCAACTCTACGGGGCCGTAGTGCAGGCCATGAGTCGAGGCTGGGATGGCGAGTAAGA GGCGACCCCGCCCGGCAGCCCCCATCCATCTGTGTCTGTCTGTTGGCCTGTATCTGTTGT AGCCCAGGCTCCCCAAGCTTCCCTGCATCTTGGTCCTTGTCCCCTTGGCCACACTGGAGA GGTGATGGGGCAGGGCTGGGTCTCAGTATCCTAGAGTCCAGCTGCAGAAGGAGTGGCTTT TCCTCCAGGAAGGGGCTTCTGGGTGTCCCCTCATCCCCAGTAGCCTCTTTCTTGCGTTTC TTTTTACCTTTTTTGGCACTCCCTCTGACCCCGCGATGAGTGTTTTGGTGGCAGAGGTGG GATGAGCTGGAAAGGTATGGAGGTGGGAGAGGATGGGGCTCTTCTGTCTGTCCTGCTTCT TCAGGTGAGTGCAGGCCAAGGCGGGGGTGAGATGGCTGAGCTTCCAGCGCCTTCTGTCCT GCCTGCCCAGTCCCTTCACTGCTTTCCTGCCCCAAGATGGCTTGCTTTTCACAAATAAAG AGAAAGAGCAGCTTTAGCCTTCTTGGTGGAATCCCAGGCAGTGGGAGCAGAATCAGAACT GCCAGGGAAGGGAAGGGGGACCTGGGTCTCAATGGGTCTCATTTGAGTCTCGCGGGCTGT GCAGATGCCCTGACAGAGTCGGTTTCCTTTGGCGGCATTCCCTTTCCCTCATTCAGCACT TCTGCTGGGAACTCCCTGACTATTCCGCTGCTGCAGGAACCCAGCTAGCTGGCCAGGTGG GGAGGGGCTGGGGACCGGCCAGGAAGGAGGGGTGACTTCATCCCAGAGAGACCCGAGTTC CCCCAGCCCTTCATCACCAACCCGCTCCTGCAGGAGTGAGTCTTACCTCCCCTGGCCCTC CTTTCTGGCTCAGCCTGCAGCGACTGTGAGGCCACAGCTCCTCAGATTCACTGCCCGCTG TGTGCCAGTACTCAGGCAGCTGGAGAGAAGAGAAGGCAGCAGCAGAGGCCCCCGCCCTCA CCCCAGCCATCTGCACTTGTACCATTTGCTCTGTGCTGACTGTGGTCCTATAAATTCATG AGAAATAAACTGGTTCTGTGTGCAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_021257 unedited
NACGTTAAGATTTTGTAATACGACTTACTATNAGGGCGGCCGCGCATTCCCGGGATCGCG TCGCGNGAGAGATGGCGCGGCACGTGCGGTGACGGCACCCGAGCCCTGAGGGTCCCAGCC CCGCGCTCCGCGTCCCCGGGACAGCATGGAGCGCCCGGAGCCCGAGCTGATCCGGCAGAG CTGGCGGGCAGTGAGCCGCAGCCCGCTGGAGCACGGCACCGTCCTGTTTGCCAGGCTGTT TGCCCTGGAGCCTGACCTGCTGCCCCTCTTCCAGTACAACTGCCGCCAGTTCTCCAGCCC AGAGGACTGTCTCTCCTCGCCTGAGTTCCTGGACCACATCAGGAAGGTGATGCTCGTGAT TGATGCTGCAGTGACCAATGTGGAAGACCTGTCCTCACTGGAGGAGTACCTTGCCAGCCT GGGCAGGAAGCACCGGGCAGTGGGTGTGAAGCTCAGCTCCTTCTCGACAGTGGGTGAGTC TCTGCTCTACATGCTGGAGAAGTGTCTGGGCCCTGCCTTCACACCAGCCACACGGGCTGC CTGGAGCCAACTCTACGGGGCCGTAGTGCAGGCCATGAGTCGAGGCTGGGATGGCGAGTA AGAGGCGACCCCGCCCGGCAGCCCCCATCCATCTGTGTCTGTCTGTTGGCCTGTATCTGT TGTAGCCCATGCTCCCCAAGCTTCCCTGCATCTTGGTCCTTGTCCCCTTGGCCACACTGG AGAGGTGATGGGGCAGGGCTGGGTCTCAGTATCCTAGAGTCCAGCTGCAGAAGGAGTGGC TTTTCCTCCAGGAAAGGGCTTCTGGGTGTCCCCTCATCCCCAGTAGCCTCTTTCTTGCGT TTCTTTTTACCTTTTTTGGCACTCCCTCTGACCCCGCGATGAGTGTTTTGGTGGCAGAAG TGGGATGAGC |
| Restriction Sites | Please inquire |
| ACCN | NM_021257 |
| Insert Size | 1711 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_021257.3, NP_067080.1 |
| RefSeq Size | 1885 bp |
| RefSeq ORF | 456 bp |
| Locus ID | 58157 |
| UniProt ID | Q9NPG2 |
| Gene Summary | This gene encodes an oxygen-binding protein that is distantly related to members of the globin gene family. It is highly conserved among other vertebrates. It is expressed in the central and peripheral nervous system where it may be involved in increasing oxygen availability and providing protection under hypoxic/ischemic conditions. [provided by RefSeq, Jul 2008] |
Citations (5)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
ER stress mediated regulation of miR23a confer Hela cells better adaptability to utilize glycolytic pathway
,Aswini, P;Grace Raji, R;Haritha, K;Lincy, E;Sameer Kumar, VB;,
J. Cell. Biochem.
,PubMed ID 29377281
[NGB]
|
|
Neuroglobin overexpression plays a pivotal role in neuroprotection through mitochondrial raft-like microdomains in neuroblastoma SK-N-BE2 cells
,Garofalo, T;Ferri, A;Sorice, M;Azmoon, P;Grasso, M;Mattei, V;Capozzi, A;Manganelli, V;Misasi, R;,
Mol. Cell. Neurosci.
,PubMed ID 29378245
[NGB]
|
|
Neuroglobin regulates hypoxic response of neuronal cells through Hif-1a- and Nrf2-mediated mechanism
,Kalpana B Hota, Sunil K Hota, Ravi B Srivastava & Shashi B Singh,
Journal of Cerebral Blood Flow & Metabolism 32, 1046-1060 doi:10.1038/jcbfm.2012.21
[NGB]
|
|
14-3-3 Binding and Phosphorylation of Neuroglobin during Hypoxia Modulate Six-to-Five Heme Pocket Coordination and Rate of Nitrite Reduction to Nitric Oxide
,Thottala Jayaraman, Jesús Tejero, Bill B. Chen, Arlin B. Blood, Sheila Frizzell, Calli Shapiro, Mauro Tiso, Brian L. Hood, Xunde Wang, Xuejun Zhao, Thomas P. Conrads, Rama K. Mallampalli, and Mark T. Gladwin,
J. Biol. Chem., Dec 2011; 286: 42679 - 42689.
[NGB]
|
|
14-3-3 Binding and Phosphorylation of Neuroglobin during Hypoxia Modulate Six-to-Five Heme Pocket Coordination and Rate of Nitrite Reduction to Nitric Oxide *
,null,
The Journal of Biological Chemistry
,PubMed ID 21965683
[NGB]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC207482 | NGB (Myc-DDK-tagged)-Human neuroglobin (NGB) |
CNY 1,200.00 |
|
| RC207482L1 | Lenti ORF clone of Human neuroglobin (NGB), Myc-DDK-tagged |
CNY 3,600.00 |
|
| RC207482L2 | Lenti ORF clone of Human neuroglobin (NGB), mGFP tagged |
CNY 5,890.00 |
|
| RC207482L3 | Lenti ORF clone of Human neuroglobin (NGB), Myc-DDK-tagged |
CNY 3,600.00 |
|
| RC207482L4 | Lenti ORF clone of Human neuroglobin (NGB), mGFP tagged |
CNY 3,600.00 |
|
| RG207482 | NGB (tGFP-tagged) - Human neuroglobin (NGB) |
CNY 2,800.00 |
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