United States
Germany
Japan
United Kingdom
China
PPAR gamma (PPARG) (NM_138712) Human Untagged Clone
CAT＃: SC124177
PPARG (untagged)-Human peroxisome proliferator-activated receptor gamma (PPARG), transcript variant 1
CNY 5,488.00
| Cited in 4 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_138712 edited
GGCGCCCGCGCCCGCCCCCGCGCCGGGCCCGGCTCGGCCCGACCCGGCTCCGCCGCGGGC AGGCGGGGCCCAGCGCACTCGGAGCCCGAGCCCGAGCCGCAGCTGCCGCCTGGGGCGCTT GGGTCGGCCTCGAGGACACCGGAGAGGGGCGCCACGCCGCCGTGGCCGCAGATTTGAAAG AAGCCAACACTAAACCACAAATATACAACAAGGCCATTTTCTCAAACGAGAGTCAGCCTT TAACGAAATGACCATGGTTGACACAGAGATGCCATTCTGGCCCACCAACTTTGGGATCAG CTCCGTGGATCTCTCCGTAATGGAAGACCACTCCCACTCCTTTGATATCAAGCCCTTCAC TACTGTTGACTTCTCCAGCATTTCTACTCCACATTACGAAGACATTCCATTCACAAGAAC AGATCCAGTGGTTGCAGATTACAAGTATGACCTGAAACTTCAAGAGTACCAAAGTGCAAT CAAAGTGGAGCCTGCATCTCCACCTTATTATTCTGAGAAGACTCAGCTCTACAATAAGCC TCATGAAGAGCCTTCCAACTCCCTCATGGCAATTGAATGTCGTGTCTGTGGAGATAAAGC TTCTGGATTTCACTATGGAGTTCATGCTTGTGAAGGATGCAAGGGTTTCTTCCGGAGAAC AATCAGATTGAAGCTTATCTATGACAGATGTGATCTTAACTGTCGGATCCACAAAAAAAG TAGAAATAAATGTCAGTACTGTCGGTTTCAGAAATGCCTTGCAGTGGGGATGTCTCATAA TGCCATCAGGTTTGGGCGGATGCCACAGGCCGAGAAGGAGAAGCTGTTGGCGGAGATCTC CAGTGATATCGACCAGCTGAATCCAGAGTCCGCTGACCTCCGGGCCCTGGCAAAACATTT GTATGACTCATACATAAAGTCCTTCCCGCTGACCAAAGCAAAGGCGAGGGCGATCTTGAC AGGAAAGACAACAGACAAATCACCATTCGTTATCTATGACATGAATTCCTTAATGATGGG AGAAGATAAAATCAAGTTCAAACACATCACCCCCCTGCAGGAGCAGAGCAAAGAGGTGGC CATCCGCATCTTTCAGGGCTGCCAGTTTCGCTCCGTGGAGGCTGTGCAGGAGATCACAGA GTATGCCAAAAGCATTCCTGGTTTTGTAAATCTTGACTTGAACGACCAAGTAACTCTCCT CAAATATGGAGTCCACGAGATCATTTACACAATGCTGGCCTCCTTGATGAATAAAGATGG GGTTCTCATATCCGAGGGCCAAGGCTTCATGACAAGGGAGTTTCTAAAGAGCCTGCGAAA GCCTTTTGGTGACTTTATGGAGCCCAAGTTTGAGTTTGCTGTGAAGTTCAATGCACTGGA ATTAGATGACAGCGACTTGGCAATATTTATTGCTGTCATTATTCTCAGTGGAGACCGCCC AGGTTTGCTGAATGTGAAGCCCATTGAAGACATTCAAGACAACCTGCTACAAGCCCTGGA GCTCCAGCTGAAGCTGAACCACCCTGAGTCCTCACAGCTGTTTGCCAAGCTGCTCCAGAA AATGACAGACCTCAGACAGATTGTCACGGAACACGTGCAGCTACTGCAGGTGATCAAGAA GACGGAGACAGACATGAGTCTTCACCCGCTCCTGCAGGAGATCTACAAGGACTTGTACTA GCAGAGAGTCCTGAGCCACTGCCAACATTTCCCTTCTTCCAGTTGCACTATTCTGAGGGA AAATCTGACACCTAAGAAATTTACTGTGAAAAAGCATTTTAAAAAGAAAAGGTTTTAGAA TATGATCTATTTTATGCATATTGTTTATAAAGACACATTTACAATTTACTTTTAATAT TAAAAATTACCATATTATGAAAAAAAAAAAAAAAAAAAA >OriGene 5' read for NM_138712 unedited
CCAGCATTTTGTAATACGACTTCACTATAGGGCGGCCGCGATTCGGCACCANAGCCGGCG CCCGCGCCCGCCCCCGCGCCGGGCCCGGCTCGGCCCGACCCGGCTCCGCCGCGGGCAGGC GGGGCCCAGCGCACTCGGAGCCCGAGCCCGAGCCGCAGCTGCCGCCTGGGGCGCTTGGGT CGGCCTCGAGGACACCGGAGAGGGGCGCCACGCCGCCGTGGCCGCAGATTTGAAAGAAGC CAACACTAAACCACAAATATACAACAAGGCCATTTTCTCAAACGAGAGTCAGCCTTTAAC GAAATGACCATGGTTGACACAGAGATGCCATTCTGGCCCACCAACTTTGGGATCAGCTCC GTGGATCTCTCCGTAATGGAAGACCACTCCCACTCCTTTGATATCAAGCCCTTCACTACT GTTGACTTCTCCAGCATTTCTACTCCACATTACGAAGACATTCCATTCACAAGAACAGAT CCAGTGGTTGCAGATTACAAGTATGACCTGAAACTTCAAGAGTACCAAAGTGCAATCAAA GTGGAGCCTGCATCTCCACCTTATTATTCTGAGAAGACTCAGCTCTACAATAAGCCTCAT GAAGAGCCTTCCAACTCCCTCATGGCAATTGAATGTCGTGTCTGTGGAGATAAAGCTTCT GGATTTCACTATGGAGTTCATGCTTGTGAAGGGATGCAGGGTTTCTTCCGGAGAAACATC AGATTGAAGCTTATCTATGACAGATGTGATCTTAACTGTCGGATCCACAAAAAAAGTAGA AATAAATGTCAGTACTGTCGGTTTCAGAAATGCCTTGCAGTGGGGATGTCTCATAATGCC ATCAGGTTTGGGGCGGATGCCACAGGCCGAGNAAGAGAAAGCTGTGGCCGGAAATCTCCA GTGATATCGACCAGCTGAATCCAGAGTCGCTGACCTCCGGCCCTGGCAAACTTTGTATGA CTCATCATAAAGTCTTCC >OriGene 3' read for NM_138712 unedited
GCCGCGCCATTTGGGTGATGGCAACTTCCCAGTTTCGGNAAAGCACTGGGGCAGGGTCAC AGGGATGCCACCCGGGTTCTGTTCAGGAAAACAGCTATGACCGCGGCCGCAATCTAGAGT CGAGTTTTTTTTTTTTTTTTTTTTCATAATATGGTAATTTTTAATATTAAAAGTAAATTG TAAATGTGTCTTTATAAACAATATGCATAAAATAGATCATATTCTAAAACCTTTTCTTTT TAAAATGCTTTTTCACAGTAAATTTCTTAGGTGTCAGATTTTCCCTCAGAATAGTGCAAC TGGAAAAAGGGAAATGTTGGCAGTGGCTCAGGACTCTCTGCTAGTACAAGTCCTTGTAGA TCTCCTGCAGGAGCGGGTGAAGACTCATGTCTGTCTCCGTTTTCTTGATCACCTGCAGTA GCTGCACGTGTTCCGTGACAATCTGTCTGAGGTCTGTCATTTTCTGGAGCAGCTTGGCAA ACAGCTGTGAGGACTCAGGGTGGTTCAGCTTCAGCTGGAGCTCCAGGGCTTGTAGCAGGT TGTCTTGAATGTCTTCAATGGGCTTCACATTCAGAAAACCTGGGCGGTCTCCACTGAGAA TAATGACAGCAATAAATATTGCCAAGTCGCTGTCATCTAATTCCAGTGCATTGAACTTCA CAGCAAACTCAAACTTGGGCTCAATAAAGTGACCAAAAGGCTTTCGCAGGCTCTTTAGAA ACTCCCTTGTCATGAAGTCTTGGCCCTCCGAATATGAAACCCTATCTTTTTTCTTAAGGA GGCCCGCTTGGGGTAATGAATCTCGGGACTCCATATTTTAAGAGAATACCTCGTCCGTTA AGTCAATATTACAAACCAGGAATGCTTTTGGCATCTGTGGTGGACCCCAGCAAAACCTCG CAGAAAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_138712 |
| Insert Size | 2000 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_138712.2, NP_619726.1 |
| RefSeq Size | 1883 bp |
| RefSeq ORF | 1428 bp |
| Locus ID | 5468 |
| UniProt ID | P37231 |
| Domains | HOLI, zf-C4 |
| Protein Families | Druggable Genome, Nuclear Hormone Receptor, Transcription Factors |
| Protein Pathways | Huntington's disease, Pathways in cancer, PPAR signaling pathway, Thyroid cancer |
| Gene Summary | This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) differs in the 5' UTR and 5' coding region compared to variant 2. Variants 1, 3, 4, 6, and 7 all encode the same isoform (1), which has a shorter, distinct N-terminus compared to isoform 2. |
Citations (4)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Halogenated bisphenol a analogues induce PPARγ-independent toxicity within human hepatocellular carcinoma cells
,null,
Current Research in Toxicology
,PubMed ID 35734227
[PPARG]
|
|
A2E induces the transactivation of RARs, PPARs and RXRs and its effects are counteracted by norbixin in retinal pigment epithelium cells in vitro
,Fontaine, V;Fournie, M;Monteiro, E;Boumedine, T;,
bioRxiv
[PPARG]
|
|
Rosiglitazone rescues human neural stem cells from amyloid-beta induced ER stress via PPARγ dependent signaling
,Lin, CH;Nicol, CJB;Cheng, YC;Chen, SJ;Yen, CH;Huang, RN;Chiang, MC;,
Exp. Cell Res.
,PubMed ID 29964054
[PPARG]
|
|
Forkhead Box Transcription Factors of the FOXA Class Are Required for Basal Transcription of Angiotensin-Converting Enzyme 2
,null,
Journal of the Endocrine Society
,PubMed ID 29082356
[PPARG]
|
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201538 | PPARG (Myc-DDK-tagged)-Human peroxisome proliferator-activated receptor gamma (PPARG), transcript variant 1 |
CNY 5,488.00 |
|
| RC201538L3 | Lenti ORF clone of Human peroxisome proliferator-activated receptor gamma (PPARG), transcript variant 1, Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC201538L4 | Lenti ORF clone of Human peroxisome proliferator-activated receptor gamma (PPARG), transcript variant 1, mGFP tagged |
CNY 7,888.00 |
|
| RG201538 | PPARG (tGFP-tagged) - Human peroxisome proliferator-activated receptor gamma (PPARG), transcript variant 1 |
CNY 7,088.00 |
|
| SC317792 | PPARG (untagged)-Human peroxisome proliferator-activated receptor gamma (PPARG), transcript variant 1 |
CNY 7,220.00 |
|
| SC322218 | PPARG (untagged)-Human peroxisome proliferator-activated receptor gamma (PPARG), transcript variant 1 |
CNY 5,488.00 |
其它PPAR gamma产品
