United States
Germany
Japan
United Kingdom
China
LTB (NM_002341) Human Untagged Clone
CAT＃: SC125270
LTB (untagged)-Human lymphotoxin beta (TNF superfamily, member 3) (LTB), transcript variant 1
CNY 3,600.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | p33; TNFC; TNFSF3; TNLG1C |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC125270 sequence for NM_002341 edited (data generated by NextGen Sequencing)
ATGGGGGCACTGGGGCTGGAGGGCAGGGGTGGGAGGCTCCAGGGGAGGGGTTCCCTCCTG CTAGCTGTGGCAGGAGCCACTTCTCTGGTGACCTTGTTGCTGGCGGTGCCTATCACTGTC CTGGCTGTGCTGGCCTTAGTGCCCCAGGATCAGGGAGGACTGGTAACGGAGACGGCCGAC CCCGGGGCACAGGCCCAGCAAGGACTGGGGTTTCAGAAGCTGCCAGAGGAGGAGCCAGAA ACAGATCTCAGCCCCGGGCTCCCAGCTGCCCACCTCATAGGCGCTCCGCTGAAGGGGCAG GGGCTAGGCTGGGAGACGACGAAGGAACAGGCGTTTCTGACGAGCGGGACGCAGTTCTCG GACGCCGAGGGGCTGGCGCTCCCGCAGGACGGCCTCTATTACCTCTACTGTCTCGTCGGC TACCGGGGCCGGGCGCCCCCTGGCGGCGGGGACCCCCAGGGCCGCTCGGTCACGCTGCGC AGCTCTCTGTACCGGGCGGGGGGCGCCTACGGGCCGGGCACTCCCGAGCTGCTGCTCGAG GGCGCCGAGACGGTGACTCCAGTGCTGGACCCGGCCAGGAGACAAGGGTACGGGCCTCTC TGGTACACGAGCGTGGGGTTCGGCGGCCTGGTGCAGCTCCGGAGGGGCGAGAGGGTGTAC GTCAACATCAGTCACCCCGATATGGTGGACTTCGCGAGAGGGAAGACCTTCTTTGGGGCC GTGATGGTGGGGTGA Clone variation with respect to NM_002341.1 >OriGene 5' read for NM_002341 unedited
TCACCAATCGTAATACGCGCGACTATATGGCGGCCGCGAATTCGGCACCAGAAAGTCCCA GCCAGGTGTGCAGGTCTACAGGGAGGGGGTGGGCCCGTCCCTGAGGTATGAAAGCCCCCT GCTCTGGCTCTGGTTCAGTCTCAATGGGGGCACTGGGGCTGGAGGGCAGGGGTGGGAGGC TCCAGGGGAGGGGTTCCCTCCTGCTAGCTGTGGCAGGAGCCACTTCTCTGGTGACCTTGT TGCTGGCGGTGCCTATCACTGTCCTGGCTGTGCTGGCCTTAGTGCCCCAGGATCAGGGAG GACTGGTAACGGAGACGGCCGACCCCGGGGCACAGGCCCAGCAAGGACTGGGGTTTCAGA AGCTGCCAGAGGAGGAGCCAGAAACAGATCTCAGCCCCGGGCTCCCAGCTGCCCACCTCA TAGGCGCTCCGCTGAAGGGGCAGGGGCTAGGCTGGGAGACGACGAAGGAACAGGCGTTTC TGACGAGCGGGACGCAGTTCTCGGACGCCGAGGGGCTGGCGCTCCCGCAGGACGGCCTCT ATTACCTCTACTGTCTCGTCGGCTACCGGGGCCGGGCGCCCCCTGGCGGCGGGGACCCCC AGGGCCGCTCGGTCACGCTGCGCAGCTCTCTGTACCGGGCGGGGGGCGCCTACGGGCCGG GCACTCCCGAGCTGCTGCTCGAGGGCGCCGAGACCGTGACTCCAGTGCTGGGACCCGCCA GGAGACAAGGGTACGGGCCTCTCTGTACACGAGCGTGNGGTTCGCGGCCTGGTGCACTN >OriGene 3' read for NM_002341 unedited
GTTGCAACTTCCCGGCCAGGAGAGGCACTGGGGAGGGGTCACAGGGATGCCACCCGGGAT CTGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTT TTTTATCGGCAGCACTGAAGCTTTCCATTCTTTATTTTCATCAGGTTCAAAATCAATTTC CAAACAGTCTCCTACATTTTTCCCACTGCCATGGGGTCCTGGGCGTCCGGGCCCCCAATA TTCACGCACTCGCACCACGCACTCATATTCCCTCACCCCACCATCACGGCCCCAAAGAAG GTCTTCCCTCTCGCGAAGTCCACCATATCGGGGTGACTGATGTTGACGTACACCCTCTCG CCCCTCCGGAGCTGCACCAGGCCGCCGAACCCCACGCTCGTGTACCAGAGAGGCCCGTAC CCTTGTCTCCTGGCCGGGTCCAGCACTGGAGTCACCGTCTCGGCGCCCTCGAGCAGCAGC TCGGGAGTGCCCGGCCCGTAGGCGCCCCCCGCCCGGTACAGAGAGCTGCGCAGCGTGACC GAGCGNGCCCCTGGGGTCCCCGCCGCCAGGGGGCGCCCGGCCCCGGTAGCCGACNAAGCA GTAGAGGTAATAGAGGCCCGTCTGCGGNNAGCGCCAGCCCCTCGCGTCCGANGAACTGCG TCCCGCTCGTCAGAAACGCCTGTCCCTCGTCGTCTCCCAGCCTAGCCCCTGCCCCTTCAG CGGACGGCCTTATAGTTGGCAACTTGGACCCCGGCCCTAGTAT |
| Restriction Sites | Please inquire |
| ACCN | NM_002341 |
| Insert Size | 900 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_002341.1, NP_002332.1 |
| RefSeq Size | 894 bp |
| RefSeq ORF | 735 bp |
| Locus ID | 4050 |
| UniProt ID | Q06643 |
| Domains | TNF |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Cytokine-cytokine receptor interaction |
| Gene Summary | Lymphotoxin beta is a type II membrane protein of the TNF family. It anchors lymphotoxin-alpha to the cell surface through heterotrimer formation. The predominant form on the lymphocyte surface is the lymphotoxin-alpha 1/beta 2 complex (e.g. 1 molecule alpha/2 molecules beta) and this complex is the primary ligand for the lymphotoxin-beta receptor. The minor complex is lymphotoxin-alpha 2/beta 1. LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue. Lymphotoxin-beta isoform b is unable to complex with lymphotoxin-alpha suggesting a function for lymphotoxin-beta which is independent of lympyhotoxin-alpha. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008] Transcript Variant: This splice variant (1) represents the longer transcript, encodes the longer isoform (a), and can form the heterotrimeric complex with lymphotoxin-alpha. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC210134 | LTB (Myc-DDK-tagged)-Human lymphotoxin beta (TNF superfamily, member 3) (LTB), transcript variant 1 |
CNY 3,840.00 |
|
| RC210134L3 | Lenti-ORF clone of LTB (Myc-DDK-tagged)-Human lymphotoxin beta (TNF superfamily, member 3) (LTB), transcript variant 1 |
CNY 5,890.00 |
|
| RC210134L4 | Lenti-ORF clone of LTB (mGFP-tagged)-Human lymphotoxin beta (TNF superfamily, member 3) (LTB), transcript variant 1 |
CNY 5,890.00 |
|
| RG210134 | LTB (tGFP-tagged) - Human lymphotoxin beta (TNF superfamily, member 3) (LTB), transcript variant 1 |
CNY 5,440.00 |
