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ETS1 (NM_005238) Human Untagged Clone
CAT＃: SC125359
ETS1 (untagged)-Human v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) (ETS1), transcript variant 2
CNY 5,488.00
| Cited in 3 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | c-ets-1; ETS-1; EWSR2; p54 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC125359 sequence for NM_005238 edited (data generated by NextGen Sequencing)
ATGAAGGCGGCCGTCGATCTCAAGCCGACTCTCACCATCATCAAGACGGAAAAAGTCGAT CTGGAGCTTTTCCCCTCCCCGGATATGGAATGTGCAGATGTCCCACTATTAACTCCAAGC AGCAAAGAAATGATGTCTCAAGCATTAAAAGCTACTTTCAGTGGTTTCACTAAAGAACAG CAACGACTGGGGATCCCAAAAGACCCCCGGCAGTGGACAGAAACCCATGTTCGGGACTGG GTGATGTGGGCTGTGAATGAATTCAGCCTGAAAGGTGTAGACTTCCAGAAGTTCTGTATG AATGGAGCAGCCCTCTGCGCCCTGGGTAAAGACTGCTTTCTCGAGCTGGCCCCAGACTTT GTTGGGGACATCTTATGGGAACATCTAGAGATCCTGCAGAAAGAGGATGTGAAACCATAT CAAGTTAATGGAGTCAACCCAGCCTATCCAGAATCCCGCTATACCTCGGATTACTTCATT AGCTATGGTATTGAGCATGCCCAGTGTGTTCCACCATCGGAGTTCTCAGAGCCCAGCTTC ATCACAGAGTCCTATCAGACGCTCCATCCCATCAGCTCGGAAGAGCTCCTCTCCCTCAAG TATGAGAATGACTACCCCTCGGTCATTCTCCGAGACCCTCTCCAGACAGACACCTTGCAG AATGACTACTTTGCTATCAAACAAGAAGTCGTCACCCCAGACAACATGTGCATGGGGAGG ACCAGTCGTGGTAAACTCGGGGGCCAGGACTCTTTTGAAAGCATAGAGAGCTACGATAGT TGTGATCGCCTCACCCAGTCCTGGAGCAGCCAGTCATCTTTCAACAGCCTGCAGCGTGTT CCCTCCTATGACAGCTTCGACTCAGAGGACTATCCGGCTGCCCTGCCCAACCACAAGCCC AAGGGCACCTTCAAGGACTATGTGCGGGACCGTGCTGACCTCAATAAGGACAAGCCTGTC ATTCCTGCTGCTGCCCTAGCTGGCTACACAGGCAGTGGACCAATCCAGCTGTGGCAGTTT CTTCTGGAATTACTCACTGATAAATCCTGTCAGTCTTTTATCAGCTGGACAGGAGATGGC TGGGAATTCAAACTTTCTGACCCAGATGAGGTGGCCAGGAGATGGGGAAAGAGGAAAAAC AAACCTAAGATGAATTATGAGAAACTGAGCCGTGGCCTACGCTACTATTACGACAAAAAC ATCATCCACAAGACAGCGGGGAAACGCTACGTGTACCGCTTTGTGTGTGACCTGCAGAGC CTGCTGGGGTACACCCCTGAGGAGCTGCACGCCATGCTGGACGTCAAGCCAGATGCCGAC GAGTGA Clone variation with respect to NM_005238.3 1011 a=>g >OriGene 5' read for NM_005238 unedited
CCGCGAATTCGGCACGAGCGGGAATTTGAGATTTTTGGGAAGAAAGTCGGATTTCCCCCG TCCCCTTCCCCCTGTTACTAATCCTCATTAAAAAGAAAAACAACAGTAACTGCAAACTTG CTACCATCCCGTACGTCCCCCACTCCTGGCACCATGAAGGCGGCCGTCGATCTCAAGCCG ACTCTCACCATCATCAAGACGGAAAAAGTCGATCTGGAGCTTTTCCCCTCCCCGGATATG GAATGTGCAGATGTCCCACTATTAACTCCAAGCAGCAAAGAAATGATGTCTCAAGCATTA AAAGCTACTTTCAGTGGTTTCACTAAAGAACAGCAACGACTGGGGATCCCAAAAGACCCC CGGCAGTGGACAGAAACCCATGTTCGGGACTGGGTGATGTGGGCTGTGAATGAATTCAGC CTGAAAGGTGTAGACTTCCAGAAGTTCTGTATGAATGGAGCAGCCCTCTGCGCCCTGGGT AAAGACTGCTTTCTCGAGCTGGCCCCAGACTTTGTTGGGGACATCTTATGGGAACATCTA GAGATCCTGCAGAAAGAGGATGTGAAACCATATCAAGTTAATGGAGTCAACCCAGCCTAT CCAGAATCCCGCTATACCTCGGATTACTTCATTAGCTATGGTATTGAGCATGCCCCAGTG TGNTCCACCATCGGANGTCTCAGAGCCCAGCTTCATCACAGAGTCCTATCAGACGCTCCA TNCCATCAGCTCGGAAGAGCTCCTCTCCCTCAGTATGAG >OriGene 3' read for NM_005238 unedited
TATGACCGAGGCTGCAATCNAGGATNCNGAAAAATCCTTTTTTTTTTTTTTTTTTTTTGA ATGAAATTCTTTGGTTTTAATTTCACACAGGTTAAAATACAATATGAAATCAGGCTACAG TATATAAAAAACTCTCCAGCAAAATGATGTGCCAGCATCAGCTACTAAAATAAACAAACA AAAAACTCCGCCATAAGAATTTTTTTGCATGGGGTGGATAAAAAACATCGACACTTACAT CGCTACATCTCTAAGCTACCTCAGTTCTGATTTTTAAAAAGCACCTGCTTTTCCTTTTTT TCATCTTACTTCTAAATTTTCAGCTTTTAAAAAATATAAATTATATGAAAATACAAGTTG GAAAATAGTCAAACACAATATAACATCTTTTTCATCCCTATACTTCTCAGCTTAAAAAAA AAGTATTCTTAAAAAAAAAAGTTCACTAACTGAGGCAGTATTCCTGATAATCCCATTTCA ACATATATATTTCATATCTGGATATGCCCCCACCAATTCACGGTCTCTCGACAATTCCCT CGACCGTAGGCCCGACGCCTTCCACCGCCCCCGACCCCTCCCCCCGCGGGATGGCACGCT GAATACAGAAAGCGGCATCACATCCCCCCTCCGCCACCCCTCTATCGGGCCCCCCGCGCC CGCCCCCCCCCACACCCCTCCCACGCCCTCCCGCCGCGGGTGTCCCCCCCCCCCTAACCG CCGCAATCTATTCCCCCTCTATCCCCGCTCGCGCCCCTCCCCACGGTCAGCCGATCGAAC AACCGGGTGGTCACCACGCGCGCCCGCCGCGCCGCCCTTTGTTCGTCCCCCACCCGTCCC GTTCCCCGCCCACCACCTCCCCCCCCGCCACCNGCCTACTATGTGACATTTCTTCCCCGC CCCCCCCACACCTGGACCCCCATCTTATTTCGCTTCCCCCGTATCACAAATACAG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_005238 |
| Insert Size | 5410 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_005238.2, NP_005229.1 |
| RefSeq Size | 5228 bp |
| RefSeq ORF | 1326 bp |
| Locus ID | 2113 |
| UniProt ID | P14921 |
| Domains | ETS, SAM_PNT |
| Protein Families | Druggable Genome, Transcription Factors |
| Protein Pathways | Dorso-ventral axis formation, Pathways in cancer, Renal cell carcinoma |
| Gene Summary | This gene encodes a member of the ETS family of transcription factors, which are defined by the presence of a conserved ETS DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T in target genes. These proteins function either as transcriptional activators or repressors of numerous genes, and are involved in stem cell development, cell senescence and death, and tumorigenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jul 2011] Transcript Variant: This variant (2) uses an alternate promoter, and differs in the 5' UTR and 5' coding region compared to variant 1. The resulting isoform (2, also known as Ets-1 p51) is shorter with a distinct N-terminus compared to isoform 1. |
Citations (3)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Aberrant expression of NKL homeobox genes HMX2 and HMX3 interferes with cell differentiation in acute myeloid leukemia
,Nagel, S;Pommerenke, C;Meyer, C;MacLeod, RAF;Drexler, HG;,
PLoS One
,PubMed ID 33048949
[ETS1]
|
|
MiR-1-3p facilitates Th17 differentiation associating with multiple sclerosis via targeting ETS1
,LI, L;MA, X;ZHAO, Y;ZHANG, C;,
European Review for Medical and Pharmacological Sciences
,PubMed ID 32633381
[ETS1]
|
|
Up-Regulation of Bcl-xl by Hepatocyte Growth Factor in Human Mesothelioma Cells Involves ETS Transcription Factors
,Xiaobo Cao, James Littlejohn, Charles Rodarte, Lidong Zhang, Benjamin Martino, Philip Rascoe, Kamran Hamid, Daniel Jupiter, and W. Roy Smythe,
Am. J. Pathol., Nov 2009; 175: 2207 - 2216
[ETS1]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC215203 | ETS1 (Myc-DDK-tagged)-Human v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) (ETS1), transcript variant 2 |
CNY 5,488.00 |
|
| RC215203L1 | Lenti ORF clone of Human v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) (ETS1), transcript variant 2, Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC215203L2 | Lenti ORF clone of Human v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) (ETS1), transcript variant 2, mGFP tagged |
CNY 7,888.00 |
|
| RC215203L3 | Lenti ORF clone of Human v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) (ETS1), transcript variant 2, Myc-DDK-tagged |
CNY 7,888.00 |
|
| RC215203L4 | Lenti ORF clone of Human v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) (ETS1), transcript variant 2, mGFP tagged |
CNY 7,888.00 |
|
| RG215203 | ETS1 (tGFP-tagged) - Human v-ets erythroblastosis virus E26 oncogene homolog 1 (avian) (ETS1), transcript variant 2 |
CNY 7,088.00 |
