United States
Germany
Japan
United Kingdom
China
CRMP2 (DPYSL2) (NM_001386) Human Untagged Clone
CAT＃: SC126729
DPYSL2 (untagged)-Human dihydropyrimidinase-like 2 (DPYSL2), transcript variant 2
CNY 6,400.00
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CRMP-2; CRMP2; DHPRP2; DRP-2; DRP2; N2A3; ULIP-2; ULIP2 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC126729 sequence for NM_001386 edited (data generated by NextGen Sequencing)
ATGTCTTATCAGGGGAAGAAAAATATTCCACGCATCACGAGCGATCGTCTTCTGATCAAA GGAGGTAAAATTGTTAATGATGACCAGTCGTTCTATGCAGACATATACATGGAAGATGGG TTGATCAAGCAAATAGGAGAAAATCTGATTGTGCCAGGAGGAGTGAAGACCATCGAGGCC CACTCCCGGATGGTGATCCCCGGAGGAATTGACGTCCACACTCGTTTCCAGATGCCTGAT CAGGGAATGACGTCTGCTGATGATTTCTTCCAAGGAACCAAGGCGGCCCTGGCTGGGGGA ACCACTATGATCATTGACCACGTTGTTCCTGAGCCTGGGACAAGCCTGCTCGCTGCCTTT GACCAGTGGAGGGAATGGGCCGACAGCAAGTCCTGCTGTGACTACTCTCTGCATGTGGAC ATCAGCGAGTGGCATAAGGGCATCCAGGAGGAGATGGAAGCGCTTGTGAAGGATCACGGG GTAAATTCCTTCCTCGTGTACATGGCTTTCAAAGATCGCTTCCAGCTAACGGATTGCCAG ATTTATGAAGTACTGAGTGTGATCCGGGATATTGGCGCCATAGCCCAAGTCCACGCAGAA AATGGCGACATCATTGCAGAGGAGCAGCAGAGGATCCTGGATCTGGGCATCACGGGCCCC GAGGGACATGTGCTGAGCCGACCTGAGGAGGTCGAGGCCGAAGCCGTGAATCGTGCCATC ACCATCGCCAACCAGACCAACTGCCCGCTGTATATCACCAAGGTGATGAGCAAAAGCTCT GCTGAGGTCATCGCCCAGGCACGGAAGAAGGGAACTGTGGTGTATGGCGAGCCCATCACT GCCAGCTTGGGAACGGACGGCTCCCATTACTGGAGCAAGAACTGGGCCAAGGCTGCTGCC TTTGTCACCTCCCCACCCTTGAGCCCTGATCCAACCACTCCAGACTTTCTCAACTCCTTG CTGTCCTGTGGAGACCTCCAGGTCACGGGCAGTGCCCATTGCACGTTTAACACTGCCCAG AAGGCTGTAGGAAAGGACAACTTCACCCTGATTCCGGAGGGCACCAATGGCACTGAGGAG CGGATGTCCGTCATCTGGGACAAGGCTGTGGTCACTGGGAAGATGGATGAGAACCAGTTT GTGGCTGTGACCAGCACCAATGCAGCCAAAGTCTTCAACCTTTACCCCCGGAAAGGCCGC ATTGCTGTGGGATCCGATGCCGACCTGGTCATCTGGGACCCCGACAGCGTTAAAACCATC TCTGCCAAGACACACAACAGCTCTCTCGAGTACAACATCTTTGAAGGCATGGAGTGCCGC GGCTCCCCACTGGTGGTCATCAGCCAGGGGAAGATTGTCCTGGAGGACGGCACCCTGCAT GTCACCGAAGGCTCTGGACGCTACATTCCCCGGAAGCCCTTCCCTGATTTTGTTTACAAG CGTATCAAGGCAAGGAGCAGGCTGGCTGAGCTGAGAGGGGTTCCTCGTGGCCTGTATGAC GGACCTGTGTGTGAAGTGTCTGTGACGCCCAAGACAGTCACTCCAGCCTCCTCGGCCAAG ACGTCTCCTGCCAAGCAGCAGGCCCCACCTGTCCGGAACCTGCACCAGTCTGGATTCAGT TTGTCTGGTGCTCAGATTGATGACAACATTCCCCGCCGCACCACCCAGCGTATCGTGGCG CCCCCCGGTGGCCGTGCCAACATCACCAGCCTGGGCTAG Clone variation with respect to NM_001386.5 426 t=>c >OriGene 5' read for NM_001386 unedited
TTTGTATACGACTCACTATAGGGCGGCCGCGAATTCGCACGAGGCCTGTTTCTCTCTCTC CTTCTCTCTCTCTCTCTCTCTCTCTTTTTTTTCCGCCCTAGCTGGGGCTGTGTTGGAGGA GAGGAAGAAAGAGAGACAGAGGATTGCATTCATCCGTTACGTTCTTGAAATTTCCTAATA GCAAGACCAGCGAAGCGGTTGCACCCTTTTCAATCTTGCAAAGGAAAAAAACAAAACAAA ACAAAAAAAACCCAAGTCCCCTTCCCGGCAGTTTTTGCCTTAAAGCTGCCCTCTTGAAAT TAATTTTTTCCCAGGAGAGAGATGTCTTATCAGGGGAAGAAAAATATTCCACGCATCACG AGCGATCGTCTTCTGATCAAAGGAGGTAAAATTGTTAATGATGACCAGTCGTTCTATGCA GACATATACATGGAAGATGGGTTGATCAAGCAAATAGGAGAAAATCTGATTGTGCCAGGA GGAGTGAAGACCATCGAGGCCCACTCCCGGATGGTGATCCCCGGAGGAATTGACGTCCAC ACTCGTTTCCAGATGCCTGATCAGGGAATGACGTCTGCTGATGATTTCTTCCAAGGAACC AAGGCGGCCCTGGCTGGGGGACCACTATGATCATTGACCACGTTGNTCCTGAGCCTGGNG ACAGCCTGCTCGCTGCCTTTGACCAGTGGAGGGAATGGGCCGACAGCAAGTCCTGCTGTG ACTACTCNTCTGCATGTGGACATCAAGCGAGTGGCATAAGGGCATNNCAGAGGAGATGGA ANNCGCTGTGGAGGATCCACGGGGTAATTCTTCCCTCGGGACATGGCTTTACAAGATCGC TTCACTAACGGGATGCCAGATTATGAGNCCTGGGGGTGGATCCGGGGATATGGGGCCCCT ACCCCAGTTCCCGCAAAAATGGGGACTTCTTTGCAAGAGCGCAAC >OriGene 3' read for NM_001386 unedited
TAGCTTTGGACCCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTTTTTT TTTTTTTTTTTTTTTTTTTTTTTTTTGAAACAACCACATTTTGCTTTATTAGGGGTTCCA TGGGAATATAACACAGAGTTTTTAAGGAATAATAAACCCGAAACTTGGTTTTTACCATAA TTATTTTGCCATCAAAACAGGGGTTACAAAAAAAAAAGTACTTTTTTGGCTACCCACTTT ATCAGCTTTAAAACTGAAAGTTCCTCCACTCATGGGGCACAATCACAATTTCCAGGATTA AAAACCATTTATTTTTAAATCCTACACTGGTTTAAAGCATCAAGGCACTGGAGTTATTCA GTTCTGAAACACTGGCGATTTATTTTAACATTTACATATGACATTCTTTTAACAGACCCC CAAAGCAAGCCAACAGGGAAACATGCTTACACAGCCTGGAAAAATCGGCAGGGTTTAACT TGTTTTTTAAAAAAACAACCCAAACAACCAAAAATTACCCTGACCCGGGTCAGGAAAAAC AGGAAGACTCAAGGGAATACTAGAGCTGCGAGGGTTTCTTAAAATTGAAACAAAAATTGT TTTTTTCCAACTTGTTCAAATTTCCTCTAAGGGCAGGGGAGAAAAAAAGCAAAATTTTTA GGCACCCCATTTTTTTTTTTAAAAGGGCAATTCCCTTTTAAAAACCCAATAAACCACACC CCCCCAAAACCCCAAACCCCACCCGATTCCCCAAGGCAAAAGGTTAAAAAACAGGGTGGG GGAGGGAAGACCTACTTTGGGAGGTTTTCACCTTTCAAAACCAAAATGTGGTTAAAAAAA GCCGGAAAACACAATTGTTTAAAAAACTGAACACCGTTGGAAAAATGGGCACCAATCACA GGGCGGGGGTTGGCCCAAGGCCCCTTGGGGGAAGGGGCCAAAAGGAGGGGGGTGGGC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_001386 |
| Insert Size | 5000 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001386.4, NP_001377.1 |
| RefSeq Size | 4567 bp |
| RefSeq ORF | 1719 bp |
| Locus ID | 1808 |
| UniProt ID | Q16555 |
| Domains | Amidohydro_1 |
| Protein Families | Druggable Genome |
| Protein Pathways | Axon guidance |
| Gene Summary | This gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011] Transcript Variant: This variant (2) differs in the 5' UTR, lacks a portion of the 5' coding region and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (2) is shorter and has a distinct N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC209080 | DPYSL2 (Myc-DDK-tagged)-Human dihydropyrimidinase-like 2 (DPYSL2), transcript variant 2 |
CNY 6,384.00 |
|
| RC209080L1 | Lenti-ORF clone of DPYSL2 (Myc-DDK-tagged)-Human dihydropyrimidinase-like 2 (DPYSL2), transcript variant 2 |
CNY 8,784.00 |
|
| RC209080L2 | Lenti-ORF clone of DPYSL2 (mGFP-tagged)-Human dihydropyrimidinase-like 2 (DPYSL2), transcript variant 2 |
CNY 6,460.00 |
|
| RC209080L3 | Lenti-ORF clone of DPYSL2 (Myc-DDK-tagged)-Human dihydropyrimidinase-like 2 (DPYSL2), transcript variant 2 |
CNY 6,460.00 |
|
| RC209080L4 | Lenti-ORF clone of DPYSL2 (mGFP-tagged)-Human dihydropyrimidinase-like 2 (DPYSL2), transcript variant 2 |
CNY 6,460.00 |
|
| RG209080 | DPYSL2 (tGFP-tagged) - Human dihydropyrimidinase-like 2 (DPYSL2), transcript variant 2 |
CNY 5,040.00 |
