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GLEPP1 (PTPRO) (NM_030670) Human Untagged Clone
CAT＃: SC128012
PTPRO (untagged)-Human protein tyrosine phosphatase, receptor type, O (PTPRO), transcript variant 6
CNY 3,656.00
CNY 6,180.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | GLEPP1; NPHS6; PTP-OC; PTP-U2; PTPROT; PTPU2; R-PTP-O |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC128012 sequence for NM_030670 edited (data generated by NextGen Sequencing)
ATGGTTACAGAGATGAATCCCAATGTGGTAGTGATCTCCGTGCTGGCCATCCTTAGCACA CTTTTAATTGGACTGTTGCTTGTTACCCTCATTATTCTTAGGAAAAAGCATCTGCAGATG GCTAGGGAGTGTGGAGCTGGTACATTTGTCAATTTTGCATCCTTAGAGAGGGATGGAAAG CTTCCATACAACTGGMGTAAAAATGGTTTAAAGAAGAGGAAACTGACAAACCCGGTTCAA CTGGATGACTTTGATGCCTATATTAAGGATATGGCCAAAGACTCTGACTATAAATTTTCT CTTCAGTTTGAGGAGTTGAAATTGATTGGACTGGATATCCCACACTTTGCTGCAGATCTT CCACTGAATCGATGTAAAAACCGTTACACAAACATCCTACCATATGACTTCAGCCGTGTG AGATTAGTCTCCATGAATGAAGAGGAAGGTGCAGACTACATCAATGCCAACTATATTCCT GGATACAACTCACCCCAGGAGTATATTGCCACCCAGGGGCCACTGCCTGAAACCAGAAAT GACTTCTGGAAGATGGTCCTGCAACAAAAGTCTCAGATTATTGTCATGCTCACTCAGTGT AATGAGAAAAGGAGGGTGAAATGTGACCATTACTGGCCATTCACGGAAGAACCTATAGCC TATGGAGACATCACTGTGGAGATGATTTCAGAGGAAGAGCAGGACGACTGGGCCTGTAGA CACTTCCGGATCAACTATGCTGACGAGATGCAGGATGTGATGCATTTTAACTACACTGCA TGGCCTGATCATGGTGTGCCCACAGCAAATGCTGCAGAAAGTATCCTGCAGTTTGTACAC ATGGTCCGACAGCAAGCTACCAAGAGCAAAGGTCCCATGATCATTCACTGCAGTGCTGGC GTGGGACGGACAGGAACATTCATTGCCCTGGACAGGCTCTTGCAGCACATTCGGGATCAT GAGTTTGTTGACATCTTAGGGCTGGTGTCAGAAATGAGGTCATACCGGATGTCTATGGTA CAGACAGAGGAGCAGTACATTTTTATCCATCAGTGTGTGCAACTGATGTGGATGAAGAAG AAGCAGCAGTTCTGCATCAGTGATGTCATATACGAGAATGTTAGCAAGTCCTAG Clone variation with respect to NM_030670.2 196 a=>m >OriGene 5' genomic read for NM_030670 unedited
CGAATTCGGCACGAGGGCAGTAGCAAGCAGCGGGCCGATCCTGGTGGAGGGTTGGGAGGC TGCTGTCATTTTATGGGTCGGCAGCCAGAGTGAGAGTGTCCCTGCTGCCAGAGGACTACG GCGGGCTGGGCGCGGGGTCCCCGCCTCTCGCTCACCACACAGACCCCGCGCCTCCTCTGG CAGCCGCGGTGGTGGCGGCGGCAGAGCCTCGCCCACTCCAATCCCCACCCTCTCCATCCT TAGTCATTAAAGAACAGCAGCGCCTGGCACGTTCTTGGAGGACCCCGGGCGCAGAGGAGG AAAGGGAGCAGGCGCAGGGGGACTGGAAAGGCAGCATGCGCTCGCCAGGAGCAACCTCGG CGCCCAGGGTCTGAGGCTGCAGCCCCAGTTCGCCATTGTGAGCCGCCGCCGGGGGAGTCC GCTAGCGCAGCCGTGCCCCCGAGTCCCCGTCCGCGCAGCGATGGGGCACCTGCCCACGGG GATACACGGCGCCCGCCGCCTCCTGCCTCTGCTCTGGCTCTTTGTGCTGTTCAAGAATGC TACAGCTTTCCATGTAACTGTCCAAGATGANTAATAACATCGTTGTCTCATTAGAAGCTT CAGACGTCATCAGTCCAGCATCTGTGTATGTTGTGAAGATAACTGGTGAATCCAAAAATT ATTTCTTCGAAATTGAGGAATTCAACAGCACTTTGCCTCCTCCTGTTATTTTCAAGGCCA GTTATCATGGCCTTTATTATATAATCACTCTGGTAGTGGGTAATGGAAATGTG >OriGene 3' read for NM_030670 unedited
NNCCTCTCTGGACCCGCGGCCGCAATCTANNGATCGGTTTTTTTTTTTTTTTTTTATCCT TCCTGCTCCATTGTGCGCTCTGTCTCTCTTGATGGATGTAGAGGTGCAGTGCTAATCCTA TCCTTCCCACTGGTCCATATGCTTCCCAGACTTTCATGATTCTCCCATCATGCACCACTG TCATCTCCCTACCCTGTCATTGGCTCCTCTTCCCCCAGTATAGTCAGACACTCTACAGTC TGTTTACTGAACTAAATGGGCAGATTACTGTTACCTCAGCCAAGATTACTTACACCTCCA AAATCTGATCTCGTAGTCAAAACTGGAGTACAGGACGTTGAATATGTTACAAGTGTCTTC ATGAAGCTCTCAAATAAGGGCTCACATAATGGGGGAGACCAAGGTATTTTCAGACTCTGC TATCCTGAGACTCTATTGTCACTGTTGTTTTTGGTTTTAGGAGTGTCCAATCCAGCTCAT GTCTTTTTGTAACCCCGTATACAGCCCTTGTAATCAATAAAATATTTGCACAAGATATCT AGATAGATTTGGATGGTAGTATCCTGATATTACAGGCACAGATCCAATAACAGAATAATT TAGGGTTCTGGGTAGAGGGAATGGAGGTAAAGTCATCATGATGTGCAGAAGCTCCTGTTT GTTGCCAACACCAACCAAGGTGCATTGAAACTCAAAGATCTGCTACAGTACTTGTTTCTC CCTGTGACACCCATGTGANGCCAGNAGCTGGGAAGAATACTCATGTGAAGTCAGAGTCAA TACAAATGGCTACTGCTGTCTTTTGGCCCATCCATCACATCCCCCTCTAATAGTTCTAAG ACTGAACACTCGTGGAGAGCTCTTCTTCCCTTACTGGTCCGGATTCTGNACTAGGACTTG CTAACATTCTCGTATATGACCATCCTGATGCAGAACG |
| Restriction Sites | NotI-NotI |
| ACCN | NM_030670 |
| Insert Size | 5000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_030670.1, NP_109595.1 |
| RefSeq Size | 3980 bp |
| RefSeq ORF | 1134 bp |
| Locus ID | 5800 |
| UniProt ID | Q16827 |
| Domains | Y_phosphatase, PTPc_motif |
| Protein Families | Phosphatase, Transmembrane |
| Gene Summary | This gene encodes a member of the R3 subtype family of receptor-type protein tyrosine phosphatases. These proteins are localized to the apical surface of polarized cells and may have tissue-specific functions through activation of Src family kinases. This gene contains two distinct promoters, and alternatively spliced transcript variants encoding multiple isoforms have been observed. The encoded proteins may have multiple isoform-specific and tissue-specific functions, including the regulation of osteoclast production and activity, inhibition of cell proliferation and facilitation of apoptosis. This gene is a candidate tumor suppressor, and decreased expression of this gene has been observed in several types of cancer. [provided by RefSeq, May 2011] Transcript Variant: This variant (6) differs in the 5' UTR and 3' UTR, and has multiple differences in the coding region but maintains the reading frame, compared to variant 1. Variants 4 and 6 encode the same isoform (d), which is shorter than isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Truncated protein tyrosine phosphatase receptor type O suppresses AKT signaling through IQ motif containing GTPase activating protein 1 and confers sensitivity to bortezomib in multiple myeloma
,Wang, H;Baladandayuthapani, V;Wang, Z;Lin, H;Berkova, Z;Davis, RE;Yang, L;Orlowski, RZ;,
Oncotarget
,PubMed ID 29371952
[PTPRO]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC216934 | PTPRO (Myc-DDK-tagged)-Human protein tyrosine phosphatase, receptor type, O (PTPRO), transcript variant 6 |
CNY 3,656.00 |
|
| RC216934L3 | Lenti-ORF clone of PTPRO (Myc-DDK-tagged)-Human protein tyrosine phosphatase, receptor type, O (PTPRO), transcript variant 6 |
CNY 5,890.00 |
|
| RC216934L4 | Lenti-ORF clone of PTPRO (mGFP-tagged)-Human protein tyrosine phosphatase, receptor type, O (PTPRO), transcript variant 6 |
CNY 5,890.00 |
|
| RG216934 | PTPRO (tGFP-tagged) - Human protein tyrosine phosphatase, receptor type, O (PTPRO), transcript variant 6 |
CNY 4,370.00 |
