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Glutaredoxin 2 (GLRX2) (NM_197962) Human Untagged Clone
CAT＃: SC128092
GLRX2 (untagged)-Human glutaredoxin 2 (GLRX2), transcript variant 2
CNY 1,200.00
CNY 3,990.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CGI-133; GRX2 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC128092 sequence for NM_197962 edited (data generated by NextGen Sequencing)
ATGATTTGGCGCCGCGCGGCGCTGGCGGGGACGCGGCTGGTTTGGAGCAGGAGCGGCTCG GCAGGCTGGCTTGACAGGGCGGCGGGAGCTGCGGGAGCTGCGGCAGCTGCGGCCTCTGGG ATGGAGAGCAATACATCATCATCTTTGGAGAATTTAGCGACGGCGCCTGTGAACCAGATC CAAGAAACAATTTCTGATAATTGTGTGGTGATTTTCTCAAAAACATCCTGTTCTTACTGT ACAATGGCAAAAAAGCTTTTCCATGACATGAATGTTAACTATAAAGTGGTGGAACTGGAC CTGCTTGAATATGGAAACCAGTTCCAAGATGCTCTTTACAAAATGACTGGTGAAAGAACT GTTCCAAGAATATTTGTCAATGGTACTTTTATTGGAGGTGCAACTGACACTCATAGGCTT CACAAAGAAGGAAAATTGCTCCCACTAGTTCATCAGTGTTATTTAAAAAAAAGTAAGAGG AAAGAATTTCAGTGA Clone variation with respect to NM_197962.2 >OriGene 5' read for NM_197962 unedited
NGGAGTTCAAATTTGTATACGACTCACTATAGGGCGGCCGCGAATCCCGGGNAATCGTCG ACCCACGCGTCCGCGCCGCGCGGCGCTGGCGGGGACGCGGCTGGTTTGGAGCAGGAGCGG CTCGGCAGGCTGGCTTGACAGGGCGGCCGCGAATTCCCGGACCATGATTTGGCGCCGCGC GGCGCTGGCGGGGACGCGGCTGGTTTGGAGCAGGAGCGGCTCGGCAGGCTGGCTTGACAG GGCGGCGGGAGCTGCGGGAGCTGCGGCAGCTGCGGCCTCTGGGATGGAGAGCAATACATC ATCATCTTTGGAGAATTTAGCGACGGCGCCTGTGAACCAGATCCAAGAAACAATTTCTGA TAATTGTGTGGTGATTTTCTCAAAAACATCCTGTTCTTACTGTACAATGGCAAAAAAGCT TTTCCATGACATGAATGTTAACTATAAAGTGGTGGAACTGGACCTGCTTGAATATGGAAA CCAGTTCCAAGATGCTCTTTACAAAATGACTGGTGAAAGAACTGTTCCAAGAATATTTGT CAATGGTACTTTTATTGGAGGTGCAACTGACACTCATAGGCTTCACAAAGAAGGAAAATT GCTCCCACTAGTTCATCAGTGTTATTTAAAAAAAAGTAAGAGGAAAGAATTTCAGTGATG TTTATACTAATAAGTTTGCTAGTACAGTGTCAGTTATTTAAAGTGGTAATGCCCGATAAT GTCTTTTAAATGTTTGANGATGTTTTAAATACATGCATTGTCTTCACGAAGAAAGATGTA AAAATATGAACAATANATTGCGGTGGAAACCTCTTAAAAAAAAAAAAAAAGGGCGGCCGC GGTCATAGCTGTTTCCTGAACAGATCCCGGGTGGCATCCCTGTGACCCCCTCCCAGC |
| Restriction Sites | NotI-NotI |
| ACCN | NM_197962 |
| Insert Size | 700 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_197962.1, NP_932066.1 |
| RefSeq Size | 735 bp |
| RefSeq ORF | 495 bp |
| Locus ID | 51022 |
| UniProt ID | Q9NS18 |
| Protein Families | Transcription Factors |
| Gene Summary | The protein encoded by this gene is a member of the glutaredoxin family of proteins, which maintain cellular thiol homeostasis. These proteins are thiol-disulfide oxidoreductases that use a glutathione-binding site and one or two active cysteines in their active site. This gene undergoes alternative splicing to produce multiple isoforms, one of which is ubiquitously expressed and localizes to mitochondria, where it functions in mitochondrial redox homeostasis and is important for the protection against and recovery from oxidative stress. Other isoforms, which have more restrictive expression patterns, show cytosolic and nuclear localization, and are thought to function in cellular differentiation and transformation, possibly with a role in tumor progression. [provided by RefSeq, Aug 2011] Transcript Variant: This variant (2) uses an alternate 5' exon and thus differs in the 5' UTR and 5' coding region, compared to variant 1. The encoded isoform (2, also known as Grx2a or mitochondrial Grx2) has a distinct N-terminus and is shorter than isoform 1. |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC213733 | GLRX2 (Myc-DDK-tagged)-Human glutaredoxin 2 (GLRX2), transcript variant 2 |
CNY 1,320.00 |
|
| RC213733L3 | Lenti-ORF clone of GLRX2 (Myc-DDK-tagged)-Human glutaredoxin 2 (GLRX2), transcript variant 2 |
CNY 5,890.00 |
|
| RC213733L4 | Lenti-ORF clone of GLRX2 (mGFP-tagged)-Human glutaredoxin 2 (GLRX2), transcript variant 2 |
CNY 5,890.00 |
|
| RG213733 | GLRX2 (tGFP-tagged) - Human glutaredoxin 2 (GLRX2), transcript variant 2 |
CNY 4,370.00 |
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