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VR1 (TRPV1) (NM_080704) Human Untagged Clone
CAT＃: SC128105
TRPV1 (untagged)-Human transient receptor potential cation channel, subfamily V, member 1 (TRPV1), transcript variant 1
CNY 6,152.00
CNY 7,220.00
| Cited in 5 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | VR1 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC128105 sequence for NM_080704 edited (data generated by NextGen Sequencing)
ATGAAGAAATGGAGCAGCACAGACTTGGGGGCAGCTGCGGACCCACTCCAAAAGGACACC TGCCCAGACCCCCTGGATGGAGACCCTAACTCCAGGCCACCTCCAGCCAAGCCCCAGCTC TCCACGGCCAAGAGCCGCACCCGGCTCTTTGGGAAGGGTGACTCGGAGGAGGCTTTCCCA GTGGATTGCCCTCACGAGGAAGGTGAGCTGGACTCCTGCCCGACCATCACAGTCAGCCCT GTTATCACCATCCAGAGGCCAGGAGACGGCCCCACCGGTGCCAGGCTGCTGTCCCAGGAC TCTGTCGCCGCCAGCACCGAGAAGACCCTCAGGCTCTATGATCGCAGGAGTATCTTTGAA GCCGTTGCTCAGAATAACTGCCAGGATCTGGAGAGCCTGCTGCTCTTCCTGCAGAAGAGC AAGAAGCACCTCACAGACAACGAGTTCAAAGACCCTGAGACAGGGAAGACCTGTCTGCTG AAAGCCATGCTCAACCTGCACGACGGACAGAACACCACCATCCCCCTGCTCCTGGAGATC GCGCGGCAAACGGACAGCCTGAAGGAGCTTGTCAACGCCAGCTACACGGACAGCTACTAC AAGGGCCAGACAGCACTGCACATCGCCATCGAGAGACGCAACATGGCCCTGGTGACCCTC CTGGTGGAGAACGGAGCAGACGTCCAGGCTGCGGCCCATGGGGACTTCTTTAAGAAAACC AAAGGGCGGCCTGGATTCTACTTCGGTGAACTGCCCCTGTCCCTGGCCGCGTGCACCAAC CAGCTGGGCATCGTGAAGTTCCTGCTGCAGAACTCCTGGCAGACGGCCGACATCAGCGCC AGGGACTCGGTGGGCAACACGGTGCTGCACGCCCTGGTGGAGGTGGCCGACAACACGGCC GACAACACGAAGTTTGTGACGAGCATGTACAATGAGATTCTGATGCTGGGGGCCAAACTG CACCCGACGCTGAAGCTGGAGGAGCTCACCAACAAGAAGGGAATGACGCCGCTGGCTCTG GCAGCTGGGACCGGGAAGATCGGGGTCTTGGCCTATATTCTCCAGCGGGAGATCCAGGAG CCCGAGTGCAGGCACCTGTCCAGGAAGTTCACCGAGTGGGCCTACGGGCCCGTGCACTCC TCGCTGTACGACCTGTCCTGCATCGACACCTGCGAGAAGAACTCGGTGCTGGAGGTGATC GCCTACAGCAGCAGCGAGACCCCTAATCGCCACGACATGCTCTTGGTGGAGCCGCTGAAC CGACTCCTGCAGGACAAGTGGGACAGATTCGTCAAGCGCATCTTCTACTTCAACTTCCTG GTCTACTGCCTGTACATGATCATCTTCACCATGGCTGCCTACTACAGGCCCGTGGATGGC TTGCCTCCCTTTAAGATGGAAAAAATTGGAGACTATTTCCGAGTTACTGGAGAGATCCTG TCTGTGTTAGGAGGAGTCTACTTCTTTTTCCGAGGGATTCAGTATTTCCTGCAGAGGCGG CCGTCGATGAAGACCCTGTTTGTGGACAGCTACAGTGAGATGCTTTTCTTTCTGCAGTCA CTGTTCATGCTGGCCACCGTGGTGCTGTACTTCAGCCACCTCAAGGAGTATGTGGCTTCC ATGGTATTCTCCCTGGCCTTGGGCTGGACCAACATGCTCTACTACACCCGCGGTTTCCAG CAGATGGGCATCTATGCCGTCATGATAGAGAAGATGATCCTGAGAGACCTGTGCCGTTTC ATGTTTGTCTACGTCGTCTTCTTGTTCGGGTTTTCCACAGCGGTGGTGACGCTGATTGAA GACGGGAAGAATGACTCCCTGCCGTCTGAGTCCACGTCGCACAGGTGGCGGGGGCCTGCC TGCAGGCCCCCCGATAGCTCCTACAACAGCCTGTACTCCACCTGCCTGGAGCTGTTCAAG TTCACCATCGGCATGGGCGACCTGGAGTTCACTGAGAACTATGACTTCAAGGCTGTCTTC ATCATCCTGCTGCTGGCCTATGTAATTCTCACCTACATCCTCCTGCTCAACATGCTCATC GCCCTCATGGGTGAGACTGTCAACAAGATCGCACAGGAGAGCAAGAACATCTGGAAGCTG CAGAGAGCCATCACCATCCTGGACACGGAGAAGAGCTTCCTTAAGTGCATGAGGAAGGCC TTCCGCTCAGGCAAGCTGCTGCAGGTGGGGTACACACCTGATGGCAAGGACGACTACCGG TGGTGCTTCAGGGTGGACGAGGTGAACTGGACCACCTGGAACACCAACGTGGGCATCATC AACGAAGACCCGGGCAACTGTGAGGGCGTCAAGCGCACCCTGAGCTTCTCCCTGCGGTCA AGCAGAGTTTCAGGCAGACACTGGAAGAACTTTGCCCTGGTCCCCCTTTTAAGAGAGGCA AGTGCTCGAGATAGGCAGTCTGCTCAGCCCGAGGAAGTTTATCTGCGACAGTTTTCAGGG TCTCTGAAGCCAGAGGACGCTGAGGTCTTCAAGAGTCCTGCCGCTTCCGGGGAGAAGTGA Clone variation with respect to NM_080704.3 180 g=>a;1406 c=>t;1753 a=>g >OriGene 5' read for NM_080704 unedited
NGGGGGTTCGAATTTGTATACGACTCATATAGGCGGCCGCGATTGATCCGCAGGATGAAG AAATGGAGCAGCACAGACTTGGGGGCAGCTGCGGACCCACTCCAAAGGACACCTGCCCAG ACCCCCTGGATGGAGACCCTAACTCCAGGCCACCTCCAGCCAAGCCCCAGCTCTCCACGG CCAAGAGCCGCACCCGGCTCTTTGGGAAGGGTGACTCGGAGGAGGCTTTCCCAGTGGATT GCCCTCACGAGGAAGGTGAGCTGGACTCCTGCCCGACCATCACAGTCAGCCCTGTTATCA CCATCCAGAGGCCAGGAGACGGCCCCACCGGTGCCAGGCTGCTGTCCCAGGACTCTGTCG CCGCCAGCACCGAGAAGACCCTCAGGCTCTATGATCGCAGGAGTATCTTTGAAGCCGTTG CTCAGAATAACTGCCAGGATCTGGAGAGCCTGCTGCTCTTCCTGCAGAAGAGCAAGAAGC ACCTCACAGACAACGAGTTCAAAGACCCTGAGACAGGGAAGACCTGTCTGCTGAAAGCCA TGCTCAACCTGCACGACGGACAGAACACCACCATCCCCCTGCTCCTGGAGATCGCGCGGC AAACGGACAGCCTGAAGGAGCTTGTCAACGCCAGCTACACGGACAGCTACTACAAGGGCC AGACAGCACTGCACATCGCCATCGAGAGACGCAACATGGCCCTGGTGACCCTCCTGGTGG AGAACGGAGCAGACGTCCAGGCTGCGGCCCATGGGGACTTCTTTAAGAAAACCAAAGGGC GGCCTGGATTCTACTTCGGTGAACTGCCCCTGTCCCTGGCCGCGTGCACCAACCAGCTGG GCATCGTGAAGTTCCTGCTGCAGAACTCCTGC |
| Restriction Sites | Please inquire |
| ACCN | NM_080704 |
| Insert Size | 3900 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_080704.2, NP_542435.2 |
| RefSeq Size | 4163 bp |
| RefSeq ORF | 2520 bp |
| Locus ID | 7442 |
| UniProt ID | Q8NER1 |
| Protein Families | Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane |
| Protein Pathways | Neuroactive ligand-receptor interaction |
| Gene Summary | Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (1) contains a different segment in the 5' UTR, compared to variant 3. Variants 1-4 all encode the same protein. |
Citations (5)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Molecular signaling of synthetic cannabinoids: Comparison of CB1 receptor and TRPV1 channel activation
,Andersen, H;Walsh, K;,
European Journal of Pharmacology
,PubMed ID 34224700
[TRPV1]
|
|
Vitamin D is an endogenous partial agonist of the transient receptor potential vanilloid 1 channel
,Long, W;Fatehi, M;Soni, S;Panigrahi, R;Philippaert, K;Yu, Y;Kelly, R;Boonen, B;Barr, A;Golec, D;Campbell, SA;Ondrusova, K;Hubert, M;Baldwin, T;Lemieux, MJ;Light, PE;,
J. Physiol. (Lond.) 2020
,PubMed ID 32721035
[TRPV1]
|
|
Five hTRPA1 Agonists Found in Indigenous Korean Mint, Agastache rugosa
,Moon, H;Kim, MJ;Son, HJ;Kweon, HJ;Kim, JT;Kim, Y;Shim, J;Suh, BC;Rhyu, MR;,
PLoS ONE
,PubMed ID 25978436
[TRPV1]
|
|
Intracellular Long-Chain Acyl CoAs Activate TRPV1 Channels
,Yu, Y;Carter, CR;Youssef, N;Dyck, JR;Light, PE;,
PLoS ONE
,PubMed ID 24798548
[TRPV1]
|
|
Furanocoumarins are a Novel Class of Modulators for the TRPV1 Channel
,Chen, X;Sun, W;Gianaris, NG;Riley, AM;Cummins, TR;Fehrenbacher, JC;Obukhov, AG;,
J. Biol. Chem., Feb 2014.
,PubMed ID 24569998
[TRPV1]
|
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC217653 | TRPV1 (Myc-DDK-tagged)-Human transient receptor potential cation channel, subfamily V, member 1 (TRPV1), transcript variant 1 |
CNY 3,990.00 |
|
| RC217653L1 | Lenti ORF clone of Human transient receptor potential cation channel, subfamily V, member 1 (TRPV1), transcript variant 1, Myc-DDK-tagged |
CNY 8,544.00 |
|
| RC217653L2 | Lenti ORF clone of Human transient receptor potential cation channel, subfamily V, member 1 (TRPV1), transcript variant 1, mGFP tagged |
CNY 5,890.00 |
|
| RC217653L3 | Lenti ORF clone of Human transient receptor potential cation channel, subfamily V, member 1 (TRPV1), transcript variant 1, Myc-DDK-tagged |
CNY 8,544.00 |
|
| RC217653L4 | Lenti ORF clone of Human transient receptor potential cation channel, subfamily V, member 1 (TRPV1), transcript variant 1, mGFP tagged |
CNY 8,544.00 |
|
| RG217653 | TRPV1 (tGFP-tagged) - Human transient receptor potential cation channel, subfamily V, member 1 (TRPV1), transcript variant 1 |
CNY 7,744.00 |
