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CD41 (ITGA2B) (NM_000419) Human Untagged Clone
CAT＃: SC300066
ITGA2B (untagged)-Human integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) (ITGA2B)
CNY 7,240.00
Product images
CNY 6,281.00
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | BDPLT2; BDPLT16; CD41; CD41B; GP2B; GPIIb; GT; GT1; GTA; HPA3; PPP1R93 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene sequence for NM_000419 edited
TGCCTGGGAGGTTGTGGAAGAAGGAAGATGGCCAGAGCTTTGTGTCCACTGCAAGCCCTC TGGCTTCTGGAGTGGGTGCTGCTGCTCTTGGGACCTTGTGCTGCCCCTCCAGCCTGGGCC TTGAACCTGGACCCAGTGCAGCTCACCTTCTATGCAGGCCCCAATGGCAGCCAGTTTGGA TTTTCACTGGACTTCCACAAGGACAGCCATGGGAGAGTGGCCATCGTGGTGGGCGCCCCG CGGACCCTGGGCCCCAGCCAGGAGGAGACGGGCGGCGTGTTCCTGTGCCCCTGGAGGGCC GAGGGCGGCCAGTGCCCCTCGCTGCTCTTTGACCTCCGTGATGAGACCCGAAATGTAGGC TCCCAAACTTTACAAACCTTCAAGGCCCGCCAAGGACTGGGGGCGTCGGTCGTCAGCTGG AGCGACGTCATTGTGGCCTGCGCCCCCTGGCAGCACTGGAACGTCCTAGAAAAGACTGAG GAGGCTGAGAAGACGCCCGTAGGTAGCTGCTTTTTGGCTCAGCCAGAGAGCGGCCGCCGC GCCGAGTACTCCCCCTGTCGCGGGAACACCCTGAGCCGCATTTACGTGGAAAATGATTTT AGCTGGGACAAGCGTTACTGTGAAGCGGGCTTCAGCTCCGTGGTCACTCAGGCCGGAGAG CTGGTGCTTGGGGCTCCTGGCGGCTATTATTTCTTAGGTCTCCTGGCCCAGGCTCCAGTT GCGGATATTTTCTCGAGTTACCGCCCAGGCATCCTTTTGTGGCACGTGTCCTCCCAGAGC CTCTCCTTTGACTCCAGCAACCCAGAGTACTTCGACGGCTACTGGGGGTACTCGGTGGCC GTGGGCGAGTTCGACGGGGATCTCAACACTACAGAATATGTCGTCGGTGCCCCCACTTGG AGCTGGACCCTGGGAGCGGTGGAAATTTTGGATTCCTACTACCAGAGGCTGCATCGGCTG CGCGGAGAGCAGATGGCGTCGTATTTTGGGCATTCAGTGGCTGTCACTGACGTCAACGGG GATGGGAGGCATGATCTGCTGGTGGGCGCTCCACTGTATATGGAGAGCCGGGCAGACCGA AAACTGGCCGAAGTGGGGCGTGTGTATTTGTTCCTGCAGCCGCGAGGCCCCCACGCGCTG GGTGCCCCCAGCCTCCTGCTGACTGGCACACAGCTCTATGGGCGATTCGGCTCTGCCATC GCACCCCTGGGCGACCTCGACCGGGATGGCTACAATGACATTGCAGTGGCTGCCCCCTAC GGGGGTCCCAGTGGCCGGGGCCAAGTGCTGGTGTTCCTGGGTCAGAGTGAGGGGCTGAGG TCACGTCCCTCCCAGGTCCTGGACAGCCCCTTCCCCACAGGCTCTGCCTTTGGCTTCTCC CTTCGAGGTGCCGTAGACATCGATGACAACGGATACCCAGACCTGATCGTGGGAGCTTAC GGGGCCAACCAGGTGGCTGTGTACAGAGCTCAGCCAGTGGTGAAGGCCTCTGTCCAGCTA CTGGTGCAAGATTCACTGAATCCTGCTGTGAAGAGCTGTGTCCTACCTCAGACCAAGACA CCCGTGAGCTGCTTCAACATCCAGATGTGTGTTGGAGCCACTGGGCACAACATTCCTCAG AAGCTATCCCTAAATGCCGAGCTGCAGCTGGACCGGCAGAAGCCCCGCCAGGGCCGGCGG GTGCTGCTGCTGGGCTCTCAACAGGCAGGCACCACCCTGAACCTGGATCTGGGCGGAAAG CACAGCCCCATCTGCCACACCACCATGGCCTTCCTTCGAGATGAGGCAGACTTCCGGGAC AAGCTGAGCCCCATTGTGCTCAGCCTCAATGTGTCCCTACCGCCCACGGAGGCTGGAATG GCCCCTGCTGTCGTGCTGCATGGAGACACCCATGTGCAGGAGCAGACACGAATCGTCCTG GACTGTGGGGAAGATGACGTATGTGTGCCCCAGCTTCAGCTCACTGCCAGCGTGACGGGC TCCCCGCTCCTAGTTGGGGCAGATAATGTCCTGGAGCTGCAGATGGACGCAGCCAACGAG GGCGAGGGGGCCTATGAAGCAGAGCTGGCCGTGCACCTGCCCCAGGGCGCCCACTACATG CGGGCCCTAAGCAATGTCGAGGGCTTTGAGAGACTCATCTGTAATCAGAAGAAGGAGAAT GAGACCAGGGTGGTGCTGTGTGAGCTGGGCAACCCCATGAAGAAGAACGCCCAGATAGGA ATCGCGATGTTGGTGAGCGTGGGGAATCTGGAAGAGGCTGGGGAGTCTGTGTCCTTCCAG CTGCAGATACGGAGCAAGAACAGCCAGAATCCAAACAGCAAGATTGTGCTGCTGGACGTG CCGGTCCGGGCAGAGGCCCAAGTGGAGCTGCGAGGGAACTCCTTTCCAGCCTCCCTGGTG GTGGCAGCAGAAGAAGGTGAGAGGGAGCAGAACAGCTTGGACAGCTGGGGACCCAAAGTG GAGCACACCTATGAGCTCCACAACAATGGCCCTGGGACTGTGAATGGTCTTCACCTCAGC ATCCACCTTCCGGGACAGTCCCAGCCCTCCGACCTGCTCTACATCCTGGATATACAGCCC CAGGGGGGCCTTCAGTGCTTCCCACAGCCTCCTGTCAACCCTCTCAAGGTGGACTGGGGG CTGCCCATCCCCAGCCCCTCCCCCATTCACCCGGCCCATCACAAGCGGGATCGCAGACAG ATCTTCCTGCCAGAGCCCGAGCAGCCCTCGAGGCTTCAGGATCCAGTTCTCGTAAGCTGC GACTCGGCGCCCTGTACTGTGGTGCAGTGTGACCTGCAGGAGATGGCGCGCGGGCAGCGG GCCATGGTCACGGTGCTGGCCTTCCTGTGGCTGCCCAGCCTCTACCAGAGGCCTCTGGAT CAGTTTGTGCTGCAGTCGCACGCATGGTTCAACGTGTCCTCCCTCCCCTATGCGGTGCCC CCGCTCAGCCTGCCCCGAGGGGAAGCTCAGGTGTGGACACAGCTGCTCCGGGCCTTGGAG GAGAGGGCCATTCCAATCTGGTGGGTGCTGGTGGGTGTGCTGGGTGGCCTGCTGCTGCTC ACCATCCTGGTCCTGGCCATGTGGAAGGTCGGCTTCTTCAAGCGGAACCGGCCACCCCTG GAAGAAGATGATGAAGAGGGGGAGTGATGGTGCAGCCTACACTATTCTAGCAGGAGGGTT GGGCGTGCTACCTGCACCGCCCCTTCTCCAACAAGTTGCCTCCAAGCTTTGGGTTGGAGC TGTTCCATTGGGTCCTCTTGGTGTCGTTTCCCTCCC >OriGene 5' read for NM_000419 unedited
GAGATTTGTATCGACTCCTATAGGGCGGCCGCGAATTCGCCCTTGCCTGGGAGGTTGTGG AAGAAGGAAGATGGCCAGAGCTTTGTGTCCACTGCAAGCCCTCTGGCTTCTGGAGTGGGT GCTGCTGCTCTTGGGACCTTGTGCTGCCCCTCCAGCCTGGGCCTTGAACCTGGACCCAGT GCAGCTCACCTTCTATGCAGGCCCCAATGGCAGCCAGTTTGGATTTTCACTGGACTTCCA CAAGGACAGCCATGGGAGAGTGGCCATCGTGGTGGGCGCCCCGCGGACCCTGGGCCCCAG CCAGGAGGAGACGGGCGGCGTGTTCCTGTGCCCCTGGAGGGCCGAGGGCGGCCAGTGCCC CTCGCTGCTCTTTGACCTCCGTGATGAGACCCGAAATGTAGGCTCCCAAACTTTACAAAC CTTCAAGGCCCGCCAAGGACTGGGGGCGTCGGTCGTCAGCTGGAGCGACGTCATTGTGGC CTGCGCCCCCTGGCAGCACTGGAACGTCCTAGAAAAGACTGAGGAGGCTGAGAAGACGCC CGTAGGTAGCTGCTTTTTGGCTCAGCCAGAGAGCGGCCGCCGCGCCGAGTACTCCCCCTG TCGCGGGAACACCCTGAGCCGCATTTACGTGGAAAATGATTTTAGCTGGGACAAGCGTTA CTGTGAAGCGGGCTTCAGCTCCGTGGTCACTCAGCCGGAGAGCTGGTGCTTGGGGCTCCT GGCGGCTATTATTTCTTAGTCTCCTGGCCCAGGCTCCAGTTGCGGATATTTTCTCGAGTT ACCGCCCAGGCATCCTTTGTGGCACGTGTCCTCCCAGAGCCTCTCCTTTGACTCAGCACC CAGAGTACTCGACGCTACTGGGGGTACTCGTGCGTGGGCGAGTCGACGGGATCTCACACT ACAGAATATGTCGTCGTGCCCCCACTGAGCTGACCTGGGAGCGGTGGAAATTTGATCTAC TA |
| Restriction Sites | Please inquire |
| ACCN | NM_000419 |
| Insert Size | 3300 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | The ORF of this clone is fully sequenced and found to be a perfect match to NM_000419.2. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_000419.2, NP_000410.1 |
| RefSeq Size | 3334 bp |
| RefSeq ORF | 3120 bp |
| Locus ID | 3674 |
| UniProt ID | P08514 |
| Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Transmembrane |
| Protein Pathways | Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy, ECM-receptor interaction, Focal adhesion, Hematopoietic cell lineage, Hypertrophic cardiomyopathy (HCM), Pathways in cancer, Regulation of actin cytoskeleton, Small cell lung cancer |
| Gene Summary | This gene encodes a member of the integrin alpha chain family of proteins. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor. This receptor plays a crucial role in the blood coagulation system, by mediating platelet aggregation. Mutations in this gene are associated with platelet-type bleeding disorders, which are characterized by a failure of platelet aggregation, including Glanzmann thrombasthenia. [provided by RefSeq, Jan 2016] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC222614 | ITGA2B (Myc-DDK-tagged)-Human integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) (ITGA2B) |
CNY 7,232.00 |
|
| RC222614L1 | Lenti ORF clone of Human integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) (ITGA2B), Myc-DDK-tagged |
CNY 9,632.00 |
|
| RC222614L2 | Lenti ORF clone of Human integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) (ITGA2B), mGFP tagged |
CNY 7,600.00 |
|
| RC222614L3 | Lenti ORF clone of Human integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) (ITGA2B), Myc-DDK-tagged |
CNY 7,600.00 |
|
| RC222614L4 | Lenti ORF clone of Human integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) (ITGA2B), mGFP tagged |
CNY 9,632.00 |
|
| RG222614 | ITGA2B (tGFP-tagged) - Human integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41) (ITGA2B) |
CNY 6,270.00 |
