United States
Germany
Japan
United Kingdom
China
CLN8 (NM_018941) Human Untagged Clone
CAT＃: SC320766
CLN8 (untagged)-Human ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) (CLN8)
CNY 2,400.00
CNY 2,950.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | C8orf61; EPMR; TLCD6 |
| Vector | pCMV6-AC |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>OriGene sequence for NM_018941.2
GGCACGAGGGCCAAGCGCAGGGAGCCCGGCTGAGTGGCAGCCCAGATTGAAGATGGATAC
GTGACAATCCCAGGGACCGCTGCACTGACTTCATTTCCTTAGACAAGACACAGTGTAGGG CCCGGCCCGTGTTGGCCCCAGGACTCCTTTGGAATATAGCTGTGGACAATGAATCCTGCG AGCGATGGGGGCACATCAGAGAGCATTTTTGACCTGGACTATGCATCCTGGGGGATCCGC TCCACGCTGATGGTCGCTGGCTTTGTCTTCTACTTGGGCGTCTTTGTGGTCTGCCACCAG CTGTCCTCTTCCCTGAATGCCACTTACCGTTCTTTGGTGGCCAGAGAGAAGGTCTTCTGG GACCTGGCGGCCACGCGTGCAGTCTTTGGTGTTCAGAGCACAGCCGCAGGCCTGTGGGCT CTGCTGGGGGACCCTGTGCTGCATGCCGACAAGGCGCGTGGCCAGCAGAACTGGTGCTGG TTTCACATCACGACAGCAACGGGATTCTTTTGCTTTGAAAATGTTGCAGTCCACCTGTCC AACTTGATCTTCCGGACATTTGACTTGTTTCTGGTTATCCACCATCTCTTTGCCTTTCTT GGGTTTCTTGGCTGCTTGGTCAATCTCCAAGCTGGCCACTATCTAGCTATGACCACGTTG CTCCTGGAGATGAGCACGCCCTTTACCTGCGTTTCCTGGATGCTCTTAAAGGCGGGCTGG TCCGAGTCTCTGTTTTGGAAGCTCAACCAGTGGCTGATGATTCACATGTTTCACTGCCGC ATGGTTCTAACCTACCACATGTGGTGGGTGTGTTTCTGGCACTGGGACGGCCTGGTCAGC AGCCTGTATCTGCCTCATTTGACACTGTTCCTTGTCGGACTGGCTCTGCTTACGCTAATC ATTAATCCATATTGGACCCATAAGAAGACTCAGCAGCTTCTCAATCCGGTGGACTGGAAC TTCGCACAGCCAGAAGCCAAGAGCAGGCCAGAAGGCAACGGGCAGCTGCTGCGGAAGAAG AGGCCATAGCTGCTCCAGCCGGGGCTCCGGGGCGGCAGCAGAGCTGGCACACCGATTCTG GGAAGCCCCGCGAATGATGGCTTTTGAATTAATGAGGCAGTGAATGTTTTGTGTTTACTT CTAAGGGAAATACTAACTTTCTTTCGCATTAGTATTAATTTTGAAGTAGCTACAAAGTAT TTTTAAGAAATTATAATTTTATGACTGTCTGGCAGGCTCTGTCAGTTTAGCCGCGCCGGA CCGTGTCAAGCATCTAGGAGAGGAGTCCATGGTGTCCAGGCATCGGGGCGTCACACCTGT TGAGGAGTGGGGTGGCTTTGAATGCTGGAAATGGCTTCATAGTGAAGTGCCTCCCACAGG GCGGGTGGGTCAGCGTTGACTCTTTCCAGCTGCACACTCATATGCCGTGTGTCTTATTCA GAAGTCACATTCTTTTCAGTTGGAGAGAATTGGGCTAAGATAGAAAATAACATGATTTGT TCCTTATTAAAGTTTCCCAGCGTATGAAATTCTAAGCTGGGTGGGGTGGCTCACACCCGA CGTAATCCCAGCACGTTGGGAGGCCGAGGCAGGTGGATCACTTGAGGCCAGGAGTTCGAG ACCAGCCTGGTCAAGATGGTGAAACCCCATCTCTACTAAAATTACAAAAATTAGCCGGGT GTCGTGGCACACACCTGTAATCCCAGCTATTTGGGAGGCCAAGGCAGGAGAATTGCCTGA ACCCGGGAGGCGGAGGTTGCAGTGAGCTGAGATCGCACCACTGCACTCCAGCACTCCAGC CTGGGTGACGGAGCAAGACTCTCTCTCAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | Please inquire |
| ACCN | NM_018941 |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_018941.2, NP_061764.2 |
| RefSeq Size | 4817 bp |
| RefSeq ORF | 861 bp |
| Locus ID | 2055 |
| UniProt ID | Q9UBY8 |
| Domains | TLC |
| Protein Families | Druggable Genome, Transmembrane |
| Gene Summary | This gene encodes a transmembrane protein belonging to a family of proteins containing TLC domains, which are postulated to function in lipid synthesis, transport, or sensing. The protein localizes to the endoplasmic reticulum (ER), and may recycle between the ER and ER-Golgi intermediate compartment. Mutations in this gene are associated with a disorder characterized by progressive epilepsy with cognitive disabilities (EPMR), which is a subtype of neuronal ceroid lipofuscinoses (NCL). Patients with mutations in this gene have altered levels of sphingolipid and phospholipids in the brain. [provided by RefSeq, Jul 2017] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC202936 | CLN8 (Myc-DDK-tagged)-Human ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) (CLN8) |
CNY 2,400.00 |
|
| RC202936L3 | Lenti ORF clone of Human ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) (CLN8), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC202936L4 | Lenti ORF clone of Human ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) (CLN8), mGFP tagged |
CNY 5,890.00 |
|
| RG202936 | CLN8 (tGFP-tagged) - Human ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) (CLN8) |
CNY 4,000.00 |
|
| SC113338 | CLN8 (untagged)-Human ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) (CLN8) |
CNY 2,400.00 |
