CLN8 (NM_018941) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC202936L3V
- LentiORF®
Lenti ORF particles, CLN8 (Myc-DDK tagged) - Human ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation) (CLN8), 200ul, >10^7 TU/mL
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CNY 8,170.00
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Specifications
Product Data | |
Product Name | CLN8 (NM_018941) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | C8orf61; EPMR; TLCD6 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_018941 |
ORF Size | 858 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC202936).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_018941.2 |
RefSeq Size | 7185 bp |
RefSeq ORF | 861 bp |
Locus ID | 2055 |
Domains | TLC |
Protein Families | Druggable Genome, Transmembrane |
MW | 32.8 kDa |
Gene Summary | This gene encodes a transmembrane protein belonging to a family of proteins containing TLC domains, which are postulated to function in lipid synthesis, transport, or sensing. The protein localizes to the endoplasmic reticulum (ER), and may recycle between the ER and ER-Golgi intermediate compartment. Mutations in this gene are associated with a disorder characterized by progressive epilepsy with cognitive disabilities (EPMR), which is a subtype of neuronal ceroid lipofuscinoses (NCL). Patients with mutations in this gene have altered levels of sphingolipid and phospholipids in the brain. [provided by RefSeq, Jul 2017] |
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