STK38L (NM_015000) Human Untagged Clone
CAT#: SC323597
STK38L (untagged)-Kinase deficient mutant (K119M) of Human serine/threonine kinase 38 like (STK38L)
CNY 3,656.00
CNY 7,220.00
Cited in 1 publication. |
Product images
CNY 1,999.00
CNY 2,700.00
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | NDR2 |
Vector | pCMV6-XL4 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene ORF within SC323597 sequence for NM_015000 edited (data generated by NextGen Sequencing)
ATGGCAATGACGGCAGGGACTACAACAACCTTTCCTATGAGCAACCATACCCGGGAAAGA GTGACTGTAGCCAAGCTCACATTGGAGAATTTTTATAGCAACCTAATTTTACAGCATGAA GAGAGAGAAACCAGGCAGAAGAAATTAGAAGTGGCCATGGAAGAAGAAGGATTAGCAGAT GAAGAGAAAAAGTTACGTCGATCACAACACGCTCGCAAAGAAACAGAGTTCTTACGGCTC AAAAGGACCAGACTTGGCTTGGATGACTTTGAGTCTCTGAAAGTTATAGGAAGAGGAGCT TTTGGAGAGGTGCGGTTGGTCCAGAAGAAAGATACAGGCCATATCTATGCAATGATGATA TTGAGAAAGTCTGATATGCTTGAAAAAGAGCAGGTGGCCCATATCCGAGCAGAAAGAGAT ATTTTGGTAGAAGCAGATGGTGCCTGGGTGGTGAAGATGTTTTACAGTTTTCAGGATAAG AGGAATCTTTATCTAATCATGGAATTTCTCCCTGGAGGTGACATGATGACATTGCTAATG AAGAAAGACACCTTGACAGAAGAGGAAACACAGTTCTACATTTCAGAGACTGTTCTGGCA ATAGATGCGATCCACCAGTTGGGTTTCATCCATCGGGATATTAAGCCAGACAACCTTTTA TTGGATGCCAAGGGTCATGTAAAATTATCTGATTTTGGTTTATGTACGGGATTAAAGAAA GCTCACAGGACTGAATTTTATAGAAATCTCACACACAACCCACCAAGTGACTTCTCATTT CAGAACATGAACTCAAAGAGGAAAGCAGAAACTTGGAAGAAGAACAGGAGACAACTGGCA TATTCCACAGTTGGGACACCAGATTACATTGCTCCAGAAGTATTCATGCAGACTGGTTAC AACAAATTGTGTGACTGGTGGTCTTTGGGAGTGATTATGTATGAAATGCTAATAGGATAT CCACCTTTCTGCTCTGAAACACCTCAAGAAACATACAGAAAAGTGATGAACTGGAAAGAA ACTCTGGTATTTCCTCCAGAGGTACCTATATCTGAGAAAGCCAAGGACTTAATTCTCAGA TTTTGTATTGATTCTGAAAACAGAATTGGAAATAGTGGAGTAGAAGAAATAAAAGGTCAT CCCTTTTTTGAAGGTGTCGACTGGGAGCACATAAGGGAAAGGCCAGCAGCAATCCCTATA GAAATCAAAAGCATTGATGATACTTCAAATTTTGATGACTTCCCTGAATCTGATATTTTA CAACCAGTGCCAAATACCACAGAACCGGACTACAAATCCAAAGACTGGGTTTTTCTCAAT TATACCTATAAAAGGTTTGAAGGGTTGACTCAACGTGGCTCTATCCCCACCTACATGAAA GCTGGGAAGTTATGA Clone variation with respect to NM_015000.3 356 a=>t;993 g=>a >OriGene 5' read for mutant NM_015000 unedited
ACCGCCCGTTCAGCAATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGAGCTCGTTTAGTGA ACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGCGGCCGGCTGCGGT CCGTGCGGAGGCTGAGCCGGCCGCGGGCGCGACCGGAGGCAGTTTCCGTTACTATGGCAATGACGGCAGG GACTACAACAACCTTTCCTATGAGCAACCATACCCGGGAAAGAGTGACTGTAGCCAAGCTCACATTGGAG AATTTTTATAGCAACCTAATTTTACAGCATGAAGAGAGAGAAAACCAGGGCAGAGGAAATTAGAAGTGGG CCATGGAAGAGGAGGGATTAGCAGATGAAAGAGAAAAAAGTTACGGTCCGATCACACAACCACGGCTTCG CCAAAGAAACACAGAAGTTTCTTTACCGGCCTCCAAAAGGGACCCAGAACTTGCCTGGGAAGGAACTTTG AGATTCTCCTGGAAAGTTTTAGGAAGAAGGACCCTTTTGGGAAAGTGTGCGGTGTGGTCAGAAAAGAAGA TACACAGGCCATATCATATGCATGGTAGGATTTTGAAAAGTCTCGTGATATGCTGAAAAAGAGAGCGTGG GCCCTATACCCAGAACAGAAGAGAGATATTTTGGATAAAAACATAGGGCCCGGGTGTGGAAATATGTTAT AACATTTTAGAGATAAGAGGACTCTTATCATACTCGGGAATTTTCCTCGGAGAGAGAGATGAGACTGTGC ATAGAGGAGAGAGACCTTGCGCAGAGAGAACACGTTCTATTTTCAAACGTGTGTGGCATATCGCTCTCCC CATGGGTTACATCTCGGGATATACGCAACCTTAATGATGTCACGCAGTTGAATCGGGTGCTGTACGGTAG AAGTCACGAACGAATTAGATT >SC323597 kinase domain raw sequence. By performing BLASTX analysis with this sequence against NCBI refernce protein database, you can confirm the presence of the kinase-deficient mutation
CTCGMGCATGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAGCAGAGCTCGTTTAGTGAACCGTCAG AATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGCGGCCGGCTGCGGTCCGTGCGG AGGCTGAGCCGGCCGCGGGCGCGACCGGAGGCAGTTTCCGTTACTATGGCAATGACGGCAGGGACTACAA CAACCTTTCCTATGAGCAACCATACCCGGGAAAGAGTGACTGTAG |
Restriction Sites | Please inquire |
ACCN | NM_015000 |
Insert Size | 4700 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
OTI Annotation | This kinase-deficient mutant clone was generated by created by site-directed mutagenesis from the corresponding wild-type clone. See details in "Application of active and kinase-deficient kinome collection for identification of kinases regulating hedgehog signaling." Cell. 2008 May p536-548. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | NM_015000.1, NP_055815.1 |
RefSeq Size | 4725 bp |
RefSeq ORF | 1395 bp |
Locus ID | 23012 |
UniProt ID | Q9Y2H1 |
Domains | pkinase |
Protein Families | Druggable Genome, Protein Kinase |
Gene Summary | Involved in the regulation of structural processes in differentiating and mature neuronal cells.[UniProtKB/Swiss-Prot Function] |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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Hippo kinase NDR2 inhibits IL-17 signaling by promoting Smurf1-mediated MEKK2 ubiquitination and degradation
,Ma, X;Wang, D;Li, N;Gao, P;Zhang, M;Zhang, Y;,
Mol. Immunol.
,PubMed ID 30504095
[STK38L]
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Documents
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC206074 | STK38L (Myc-DDK-tagged)-Human serine/threonine kinase 38 like (STK38L) |
CNY 5,488.00 |
|
RC206074L1 | Lenti ORF clone of Human serine/threonine kinase 38 like (STK38L), Myc-DDK-tagged |
CNY 7,888.00 |
|
RC206074L2 | Lenti ORF clone of Human serine/threonine kinase 38 like (STK38L), mGFP tagged |
CNY 5,890.00 |
|
RC206074L3 | Lenti ORF clone of Human serine/threonine kinase 38 like (STK38L), Myc-DDK-tagged |
CNY 7,888.00 |
|
RC206074L4 | Lenti ORF clone of Human serine/threonine kinase 38 like (STK38L), mGFP tagged |
CNY 7,888.00 |
|
RG206074 | STK38L (tGFP-tagged) - Human serine/threonine kinase 38 like (STK38L) |
CNY 7,088.00 |
|
SC100957 | STK38L (untagged)-Human serine/threonine kinase 38 like (STK38L) |
CNY 3,656.00 |