Insig2 (NM_133748) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR202632L4V
- LentiORF®
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Lenti ORF particles, Insig2 (GFP-tagged) - Mouse insulin induced gene 2 (Insig2), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 8,360.00
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Specifications
Product Data | |
Product Name | Insig2 (NM_133748) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | 2900053I11Rik; C730043J18Rik; Insig-2 |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_133748 |
ORF Size | 678 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR202632).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_133748.1 |
RefSeq Size | 2711 bp |
RefSeq ORF | 678 bp |
Locus ID | 72999 |
Gene Summary | Mediates feedback control of cholesterol synthesis by controlling SCAP and HMGCR. Functions by blocking the processing of sterol regulatory element-binding proteins (SREBPs). Capable of retaining the SCAP-SREBF2 complex in the ER thus preventing it from escorting SREBPs to the Golgi. Seems to regulate the ubiquitin-mediated proteasomal degradation of HMGCR.[UniProtKB/Swiss-Prot Function] |
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