Gtf2h2 (BC016231) Mouse Tagged ORF Clone Lentiviral Particle

CAT#: MR206255L3V

  • LentiORF®

Lenti ORF particles, Gtf2h2 (Myc-DDK-tagged) - Mouse general transcription factor II H, polypeptide 2 (cDNA clone MGC:28787 IMAGE:4488798), 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP



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CNY 9,975.00


货期*
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规格
    • 200 ul

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Specifications

Product Data
Product Name Gtf2h2 (BC016231) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms Btf2p44, 44kDa
Vector pLenti-C-Myc-DDK-P2A-Puro
ACCN BC016231
ORF Size 1194 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR206255).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq BC016231, AAH16231
RefSeq Size 1643 bp
RefSeq ORF 1196 bp
Locus ID 23894
Gene Summary Component of the general transcription and DNA repair factor IIH (TFIIH) core complex, which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. In NER, TFIIH acts by opening DNA around the lesion to allow the excision of the damaged oligonucleotide and its replacement by a new DNA fragment. In transcription, TFIIH has an essential role in transcription initiation. When the pre-initiation complex (PIC) has been established, TFIIH is required for promoter opening and promoter escape. Phosphorylation of the C-terminal tail (CTD) of the largest subunit of RNA polymerase II by the kinase module CAK controls the initiation of transcription. The N-terminus of GTF2H2 interacts with and regulates XPD whereas an intact C-terminus is required for a successful escape of RNAP II form the promoter.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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