Klhl15 (NM_153165) Mouse Tagged ORF Clone Lentiviral Particle

CAT＃: MR213934L4V

  • LentiORF®

Lenti ORF particles, Klhl15 (GFP-tagged) - Mouse kelch-like 15 (Drosophila) (Klhl15), transcript variant 4, 200ul, >10^7 TU/mL

ORF Plasmid: DDK tGFP

Datasheet
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CNY 8,360.00

货期*
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规格
    • 200 ul

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经常一起买 (2)
PS100093V
Lenti ORF control particles of pLenti-C-mGFP-P2A-Puro, >1x10^7 TU/ml, 0.5 ml
    • 500 ul

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暂停销售
TR30038
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Specifications

Product Data
Product Name Klhl15 (NM_153165) Mouse Tagged ORF Clone Lentiviral Particle
Synonyms 6330500C13Rik
Vector pLenti-C-mGFP-P2A-Puro
ACCN NM_153165
ORF Size 711 bp
Sequence Data
The ORF insert of this clone is exactly the same as(MR213934).
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Reference Data
RefSeq NM_153165.2, NP_694805.1
RefSeq Size 3188 bp
RefSeq ORF 714 bp
Locus ID 236904
Gene Summary Substrate-specific adapter for CUL3 E3 ubiquitin-protein ligase complex. Acts as an adapter for CUL3 to target the serine/threonine-protein phosphatase 2A (PP2A) subunit PPP2R5B for ubiquitination and subsequent proteasomal degradation, thus promoting exchange with other regulatory subunits and regulating PP2A holoenzyme composition. Acts as an adapter for CUL3 to target the DNA-end resection factor RBBP8/CtIP for ubiquitination and subsequent proteasomal degradation. Through the regulation of RBBP8/CtIP protein turnover, plays a key role in DNA damage response, favoring DNA double-strand repair through error-prone non-homologous end joining (NHEJ) over error-free, RBBP8-mediated homologous recombination (HR).[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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