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Atp8a2 (NM_015803) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR224181L4V
- LentiORF®
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Lenti ORF particles, Atp8a2 (GFP-tagged) - Mouse ATPase, aminophospholipid transporter-like, class I, type 8A, member 2 (Atp8a2), 200ul, >10^7 TU/mL
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CNY 18,810.00
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Specifications
| Product Data | |
| Product Name | Atp8a2 (NM_015803) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | agil; AI415030; Atpc1b; wl |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_015803 |
| ORF Size | 3444 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR224181).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_015803.2 |
| RefSeq Size | 3685 bp |
| RefSeq ORF | 3447 bp |
| Locus ID | 50769 |
| Gene Summary | Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. Reconstituted to liposomes, the ATP8A2:TMEM30A flippase complex predomiminantly transports phosphatidylserine (PS) and to a lesser extent phosphatidylethanolamine (PE). ATP8A2:TMEM30A may be involved in regulation of neurite outgrowth. Proposed to function in the generation and maintenance of phospholipid asymmetry in photoreceptor disk membranes and neuronal axon membranes. May be involved in vesicle trafficking in neuronal cells. Required for normal visual and auditory function; involved in photoreceptor and inner ear spiral ganglion cell survival.[UniProtKB/Swiss-Prot Function] |
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