Hand2 (NM_010402) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR227003L3V
- LentiORF®
Lenti ORF particles, Hand2 (Myc-DDK-tagged) - Mouse heart and neural crest derivatives expressed transcript 2 (Hand2), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
Product Data | |
Product Name | Hand2 (NM_010402) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | AI225906; AI661148; bHLHa26; dHAND; Ehand2; Hed; Th2; Thing2 |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_010402 |
ORF Size | 651 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR227003).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_010402.4, NP_034532.3 |
RefSeq Size | 2235 bp |
RefSeq ORF | 654 bp |
Locus ID | 15111 |
Gene Summary | Essential for cardiac morphogenesis, particularly for the formation of the right ventricle and of the aortic arch arteries. Required for vascular development and regulation of angiogenesis, possibly through a VEGF signaling pathway. Plays also an important role in limb development, particularly in the establishment of anterior-posterior polarization, acting as an upstream regulator of sonic hedgehog (SHH) induction in the limb bud. Is involved in the development of branchial arches, which give rise to unique structures in the head and neck. Binds DNA on E-box consensus sequence 5'-CANNTG-3'.[UniProtKB/Swiss-Prot Function] |
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