United States
Germany
Japan
United Kingdom
China
Hgs (NM_008244) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR227581L4V
- LentiORF®
-
Lenti ORF particles, Hgs (GFP-tagged) - Mouse HGF-regulated tyrosine kinase substrate (Hgs), transcript variant 2, 200ul, >10^7 TU/mL
Need custom lentivirus service?
Get a free quote
CNY 14,060.00
货期*
详询
规格
Product images
经常一起买 (2)
Specifications
| Product Data | |
| Product Name | Hgs (NM_008244) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | Hgr; Hrs; tn; ZFYVE8 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_008244 |
| ORF Size | 2325 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR227581).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_008244.3 |
| RefSeq Size | 2905 bp |
| RefSeq ORF | 2328 bp |
| Locus ID | 15239 |
| Gene Summary | Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin-coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (ESCRT-0 complex). The ESCRT-0 complex binds ubiquitin and acts as sorting machinery that recognizes ubiquitinated receptors and transfers them to further sequential lysosomal sorting/trafficking processes. May contribute to the efficient recruitment of SMADs to the activin receptor complex. Involved in receptor recycling via its association with the CART complex, a multiprotein complex required for efficient transferrin receptor recycling but not for EGFR degradation.[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
You may also need
Customer
Reviews
Loading...
