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EDEM1 (NM_014674) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC205655L3V
- LentiORF®
-
Lenti ORF particles, EDEM1 (Myc-DDK tagged) - Human ER degradation enhancer, mannosidase alpha-like 1 (EDEM1), 200ul, >10^7 TU/mL
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CNY 8,930.00
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规格
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Specifications
| Product Data | |
| Product Name | EDEM1 (NM_014674) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | EDEM |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_014674 |
| ORF Size | 1971 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC205655).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_014674.1, NP_055489.1 |
| RefSeq Size | 6072 bp |
| RefSeq ORF | 1974 bp |
| Locus ID | 9695 |
| Domains | Glyco_hydro_47 |
| Protein Families | Transmembrane |
| MW | 73.6 kDa |
| Gene Summary | Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. It is directly involved in endoplasmic reticulum-associated degradation (ERAD) and targets misfolded glycoproteins for degradation in an N-glycan-independent manner, probably by forming a complex with SEL1L. It has low mannosidase activity, catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2.[UniProtKB/Swiss-Prot Function] |
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