SECISBP2 (NM_024077) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC206346L2V
- LentiORF®
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Lenti ORF particles, SECISBP2 (mGFP-tagged) - Human SECIS binding protein 2 (SECISBP2), 200ul, >10^7 TU/mL
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CNY 9,975.00
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Specifications
Product Data | |
Product Name | SECISBP2 (NM_024077) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | SBP2 |
Vector | pLenti-C-mGFP |
ACCN | NM_024077 |
ORF Size | 2562 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC206346).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_024077.3 |
RefSeq Size | 3535 bp |
RefSeq ORF | 2565 bp |
Locus ID | 79048 |
Domains | Ribosomal_L7Ae |
MW | 95.4 kDa |
Gene Summary | The protein encoded by this gene is one of the essential components of the machinery involved in co-translational insertion of selenocysteine (Sec) into selenoproteins. Sec is encoded by the UGA codon, which normally signals translation termination. The recoding of UGA as Sec codon requires a Sec insertion sequence (SECIS) element; present in the 3' untranslated regions of eukaryotic selenoprotein mRNAs. This protein specifically binds to the SECIS element, which is stimulated by a Sec-specific translation elongation factor. Mutations in this gene have been associated with reduction in enzymatic activity of type II iodothyronine deiodinase (a selenoprotein) and abnormal thyroid hormone metabolism. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2017] |
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