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SECISBP2 (NM_024077) Human Untagged Clone
CAT＃: SC112316
SECISBP2 (untagged)-Human SECIS binding protein 2 (SECISBP2)
CNY 6,264.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | SBP2 |
| Vector | pCMV6-XL4 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC112316 sequence for NM_024077 edited (data generated by NextGen Sequencing)
ATGGCGTCGGAGGGGCCGCGGGAGCCCGAAAGCGAGGGCATCAAGTTATCAGCAGATGTC AAACCATTTGTCCCCAGATTTGCCGGGCTCAATGTGGCATGGTTAGAGTCCTCAGAAGCA TGTGTCTTCCCCAGCTCTGCAGCCACATACTATCCGTTTGTTCAGGAACCACCAGTGACA GAGCAGAAAATATATACTGAAGACATGGCCTTTGGAGCTTCAACTTTTCCACCTCAGTAT TTATCTTCTGAGATAACTCTTCATCCATATGCCTATTCTCCTTATACCCTTGACTCCACA CAGAATGTTTACTCAGTGCCTGGCTCCCAGTATCTTTATAACCAACCCAGTTGTTACCGA GGTTTTCAAACAGTGAAGCATCGAAATGAGAACACATGCCCTCTCCCACAAGAAATGAAA GCTCTGTTTAAGAAGAAAACCTATGATGAGAAAAAAACGTATGATCAGCAAAAGTTTGAC AGTGAAAGGGCTGATGGAACTATATCATCTGAGATAAAATCAGCTAGAGGTTCACATCAT TTGTCCATTTACGCTGAGAATAGTTTGAAATCAGATGGTTACCATAAGCGAACAGACAGG AAATCCAGAATCATTGCAAAAAATGTATCTACCTCCAAACCTGAGTTTGAATTTACCACA CTGGACTTTCCTGAACTGCAAGGTGCAGAGAACAATATGTCAGAGATACAGAAGCAACCC AAGTGGGGACCTGTCCACTCTGTCTCTACCGACATTTCTCTTCTAAGAGAAGTAGTAAAA CCAGCTGCAGTGTTATCAAAGGGTGAAATAGTGGTGAAAAATAACCCAAATGAATCTGTA ACTGCTAATGCCGCTACCAATTCTCCTTCATGTACAAGAGAGTTATCTTGGACACCAATG GGTTATGTTGTTCGACAGACATTATCTACAGAACTGTCAGCAGCCCCTAAAAATGTTACT TCTATGATAAACTTAAAGACCATTGCTTCATCAGCAGATCCTAAAAATGTTAGTATACCA TCTTCTGAAGCTTTATCTTCGGATCCTTCCTACAACAAAGAAAAACACATTATTCATCCT ACCCAAAAGTCTAAAGCATCACAAGGTAGTGACCTTGAACAAAATGAAGCCTCAAGAAAG AATAAGAAAAAGAAAGAAAAATCTACATCAAAATATGAAGTCCTGACAGTTCAAGAGCCT CCAAGGATTGAAGATGCCGAGGAATTTCCCAACCTGGCAGTTGCATCTGAAAGAAGAGAC AGAATAGAGACACCGAAATTTCAATCTAAGCAGCAGCCACAGGATAATTTTAAAAATAAT GTAAAGAAGAGCCAGCTTCCAGTGCAGTTGGACTTGGGGGGCATGCTGACAGCCCTGGAG AAGAAGCAGCACTCTCAGCATGCAAAGCAGTCCTCCAAACCAGTGGTAGTCTCAGTTGGA GCAGTGCCAGTCCTTTCCAAAGAATGTGCATCAGGGGAGAGAGGCCGCCGCATGAGTCAA ATGAAGACCCCGCACAATCCCTTGGACTCCAGCGCCCCACTGATGAAGAAAGGGAAGCAG AGGGAGATCCCCAAGGCCAAGAAGCCAACCTCACTGAAGAAGATTATTTTGAAAGAACGG CAAGAGAGAAAGCAGCGTCTCCAAGAAAATGCTGTGAGTCCAGCTTTTACCAGTGATGAC ACACAAGATGGAGAGAGTGGTGGTGATGACCAGTTTCCCGAGCAGGCAGAGCTGTCAGGG CCAGAGGGGATGGACGAACTGATCTCCACTCCTTCGGTTGAGGACAAGTCTGAAGAGCCA CCAGGCACAGAGCTCCAGAGGGACACAGAGGCCTCCCACCTTGCTCCCAATCACACCACC TTCCCTAAGATCCACAGCCGCAGATTCAGGGATTACTGCAGCCAGATGCTTAGTAAAGAA GTGGATGCTTGTGTTACCGACCTACTCAAAGAACTGGTCCGTTTCCAAGACCGTATGTAC CAGAAAGATCCAGTCAAGGCCAAGACTAAACGTCGACTTGTGTTGGGGTTGAGGGAGGTT CTCAAACACCTGAAGCTCAAAAAACTGAAATGTGTCATTATTTCTCCCAACTGTGAGAAG ATACAGTCAAAAGGTGGGCTGGATGACACTTTGCACACAATTATTGATTATGCCTGTGAG CAGAACATTCCCTTTGTGTTTGCTCTCAACCGCAAAGCTCTGGGGCGCAGTTTGAATAAG GCAGTTCCTGTCAGTGTGGTGGGGATCTTCAGCTATGATGGGGCCCAGGATCAGTTCCAC AAGATGGTTGAGCTGACAGTGGCGGCCCGACAGGCGTACAAGACCATGCTGGAGAATGTG CAGCAGGAGCTGGTGGGAGAGCCCAGGCCTCAGGCACCTCCCAGCCTACCCACACAGGGC CCCAGCTGCCCTGCAGAAGATGGCCCCCCAGCCCTGAAAGAAAAAGAAGAGCCACACTAC ATTGAAATCTGGAAAAAACATCTGGAAGCATACAGTGGATGTACCCTGGAGCTAGAAGAA TCCTTGGAGGCTTCAACCTCTCAAATGATGAATTTGAATTTATGA Clone variation with respect to NM_024077.3 >OriGene 5' read for NM_024077 unedited
ATAGGCGGGCCGCGAATTCGCACGAGGGTCGCCTGCGGGGGCGGAAACGCTTTGTCTGTC CGGCAAGCCGACGGCCCGCTGCTGGCCTCCGTGACGCGGCCTCCTCCGCGCCTCGCGGCA TGGCGTCGGAGGGGCCGCGGGAGCCCGAAAGCGAGGGCATCAAGTTATCAGCAGATGTCA AACCATTTGTCCCCAGATTTGCCGGGCTCAATGTGGCATGGTTAGAGTCCTCAGAAGCAT GTGTCTTCCCCAGCTCTGCAGCCACATACTATCCGTTTGTTCAGGAACCACCAGTGACAG AGCAGAAAATATATACTGAAGACATGGCCTTTGGAGCTTCAACTTTTCCACCTCAGTATT TATCTTCTGAGATAACTCTTCATCCATATGCCTATTCTCCTTATACCCTTGACTCCACAC AGAATGTTTACTCAGTGCCTGGCTCCCAGTATCTTTATAACCAACCCAGTTGTTACCGAG GTTTTCAAACAGTGAAGCATCGAAATGAGAACACATGCCCTCTCCCACAAGAAATGAAAG CTCTGTTTAAGAAGAAAACCTATGATGAGAAAAAAACGTATGATCAGCAAAAGTTTGACA GTGAAAGGGCTGATGGAACTATATCATCTGAGATAAAATCAGCTAGAGGTTCACATCATT TGTCCATTTACGCTGAGAATAGTTTGAAATCAGATGGTTACCATAAGCGAACAGACAGGA NATCCAGAATCATTGCANAAAATGTATCTACCTNCAAACCTGAGTTTGAAATTACCACAC TGGNACTTNTCCTGAACTGCANGGTGCANAGNNACATATGTCAGAGATACAGAAGCAACC CNAGTGGGGACCCTGTNCACTCTGNCTCTACC >OriGene 3' read for NM_024077 unedited
TGGACCGGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTTAATAATTACT CTTTATTTAAAATAAATAAGCCCTCTTACTTACAGGGNAAAATATGAAAGCAAACTCTGT CCTCCTGGTCTAAGACAGAAACCACATTCAGAATATGTTCATTGAAAAAGGAAAGATTTG TTGATTATCAAACAAATCTAGGTACTTCAATACACATTGTTTCTTTGAAAAATAAAGACT GAAAGGAATAATTCATTTCAAAAAGTCACAGGTTAGAAAACCAATTTTCCTTCTGAGGCT CATTTTAGCAAATCCTCCAAGTGTTCCCAAATCTTTTAAAAAAGCTACATCCCCTGAGAA AGGGCCCTTTCCCTGTAGCCCTCTTGCTCTGACACCAGCAGCCCTGCACCCTTCTGCCAA GTGGCTCCCTGCAGGACGGTGCTGTTGCCGGGCAGGAATGGCCCTCCATGGCAACCTCCA GCAGGCAGGAGCTCACCACCTGCTTTCTGCAAACTCACTCACTTGGCTCAGCTATTCTGC AATGGAGAGGAAGTTTCCTTAGCAGCCAAAGTATTCTAAGTATCACATTTTCCAGTATTT TCCAGATCCGTAGTGTGCTCAGAAAGCCAGAGCTGTATCACCAGGCTTTTAGAGAAGATT AACACCTGCACATCTGAGTGACCTTTAACAGGCTNCGCAGCACTGAACGCCTGCAGACAC TGCTTTATGTGCCCCTTAATGCTGATCAATTTCCAGATTCAACAGTTACACAATTACATT GTCATGAAAAACCAGAGAAAAAGCCCCAAGTCTTTTTCAGACCTTCCCTCCTTACCCAAA TACAGACCCCAGGCAGAACTTTATAAATTCAATTCATCATTGGGAGGTTGAACCTTCAGG TATTTTTAGCTCCGGGACATCCCTGATGCTTCAAAGATTTTTCAATTAAAGAAGGGGTTT TCTTTTTTTAGGCGGGGGCTTTTTCAGGACTGGGCCTGGGGAACTTA |
| Restriction Sites | NotI-NotI |
| ACCN | NM_024077 |
| Insert Size | 3630 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_024077.2, NP_076982.2 |
| RefSeq Size | 3457 bp |
| RefSeq ORF | 2565 bp |
| Locus ID | 79048 |
| UniProt ID | Q96T21 |
| Domains | Ribosomal_L7Ae |
| Gene Summary | The protein encoded by this gene is one of the essential components of the machinery involved in co-translational insertion of selenocysteine (Sec) into selenoproteins. Sec is encoded by the UGA codon, which normally signals translation termination. The recoding of UGA as Sec codon requires a Sec insertion sequence (SECIS) element; present in the 3' untranslated regions of eukaryotic selenoprotein mRNAs. This protein specifically binds to the SECIS element, which is stimulated by a Sec-specific translation elongation factor. Mutations in this gene have been associated with reduction in enzymatic activity of type II iodothyronine deiodinase (a selenoprotein) and abnormal thyroid hormone metabolism. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2017] Transcript Variant: This variant (1) represents the predominant transcript, and encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
Utilization of Selenocysteine for Site-Specific Antibody Conjugation
,Li, X;Rader, C;,
Methods Mol. Biol
,PubMed ID 28255878
[SECISBP2]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206346 | SECISBP2 (Myc-DDK-tagged)-Human SECIS binding protein 2 (SECISBP2) |
CNY 6,256.00 |
|
| RC206346L1 | Lenti ORF clone of Human SECIS binding protein 2 (SECISBP2), Myc-DDK-tagged |
CNY 8,656.00 |
|
| RC206346L2 | Lenti ORF clone of Human SECIS binding protein 2 (SECISBP2), mGFP tagged |
CNY 9,030.00 |
|
| RC206346L3 | Lenti ORF clone of Human SECIS binding protein 2 (SECISBP2), Myc-DDK-tagged |
CNY 9,030.00 |
|
| RC206346L4 | Lenti ORF clone of Human SECIS binding protein 2 (SECISBP2), mGFP tagged |
CNY 9,030.00 |
|
| RG206346 | SECISBP2 (tGFP-tagged) - Human SECIS binding protein 2 (SECISBP2) |
CNY 7,856.00 |
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