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FAM173B (ATPSCKMT) (NM_199133) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC209093L1V
- LentiORF®
-
Lenti ORF particles, FAM173B (Myc-DDK tagged) - Human family with sequence similarity 173, member B (FAM173B), 200ul, >10^7 TU/mL
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CNY 7,410.00
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规格
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Specifications
| Product Data | |
| Product Name | FAM173B (ATPSCKMT) (NM_199133) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | FAM173B; hFAM173B; JS-2 |
| Vector | pLenti-C-Myc-DDK |
| ACCN | NM_199133 |
| ORF Size | 699 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC209093).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_199133.1, NP_954584.1 |
| RefSeq Size | 2672 bp |
| RefSeq ORF | 702 bp |
| Locus ID | 134145 |
| Protein Families | Druggable Genome, Transmembrane |
| MW | 26.1 kDa |
| Gene Summary | Mitochondrial protein-lysine N-methyltransferase that trimethylates ATP synthase subunit C, ATP5MC1 and ATP5MC2. Trimethylation is required for proper incorporation of the C subunit into the ATP synthase complex and mitochondrial respiration (PubMed:29444090, PubMed:30530489). Promotes chronic pain (PubMed:29444090). Involved in persistent inflammatory and neuropathic pain: methyltransferase activity in the mitochondria of sensory neurons promotes chronic pain via a pathway that depends on the production of reactive oxygen species (ROS) and on the engagement of spinal cord microglia (PubMed:29444090).[UniProtKB/Swiss-Prot Function] |
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