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MRGX1 (MRGPRX1) (NM_147199) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC211487L3V
- LentiORF®
-
Lenti ORF particles, MRGPRX1 (Myc-DDK-tagged)-Human MAS-related GPR, member X1 (MRGPRX1), 200ul, >10^7 TU/mL
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CNY 8,360.00
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规格
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Specifications
| Product Data | |
| Product Name | MRGX1 (MRGPRX1) (NM_147199) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | GPCR; MGRG2; MRGX1; SNSR4 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_147199 |
| ORF Size | 966 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC211487).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_147199.3, NP_671732.3 |
| RefSeq Size | 1190 bp |
| RefSeq ORF | 969 bp |
| Locus ID | 259249 |
| Protein Families | Druggable Genome, GPCR, Transmembrane |
| MW | 36.3 kDa |
| Gene Summary | Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22)(PubMed:26582731). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway. Activated by the antimalarial drug, chloroquine. May mediate chloroquine-induced itch, in a histamine-independent manner.[UniProtKB/Swiss-Prot Function] |
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