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DEPDC5 (NM_014662) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC221026L3V
- LentiORF®
-
Lenti ORF particles, DEPDC5 (Myc-DDK-tagged)-Human DEP domain containing 5 (DEPDC5), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 11,210.00
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Specifications
| Product Data | |
| Product Name | DEPDC5 (NM_014662) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | DEP.5; FFEVF; FFEVF1 |
| Vector | pLenti-C-Myc-DDK-P2A-Puro |
| ACCN | NM_014662 |
| ORF Size | 4716 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC221026).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_014662.3 |
| RefSeq Size | 5458 bp |
| RefSeq ORF | 4719 bp |
| Locus ID | 9681 |
| Domains | DEP |
| MW | 177.9 kDa |
| Gene Summary | This gene encodes a member of the IML1 family of proteins involved in G-protein signaling pathways. The mechanistic target of rapamycin complex 1 (mTORC1) pathway regulates cell growth by sensing the availability of nutrients. The protein encoded by this gene is a component of the GATOR1 (GAP activity toward Rags) complex which inhibits the amino acid-sensing branch of the mTORC1 pathway. Mutations in this gene are associated with autosomal dominant familial focal epilepsy with variable foci. A single nucleotide polymorphism in an intron of this gene has been associated with an increased risk of hepatocellular carcinoma in individuals with chronic hepatitis C virus infection. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014] |
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