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WIBG (PYM1) (NM_001143853) Human Tagged ORF Clone Lentiviral Particle
CAT＃: RC227106L2V
- LentiORF®
-
Lenti ORF particles, WIBG (mGFP-tagged) - Human within bgcn homolog (Drosophila) (WIBG), transcript variant 2, 200ul, >10^7 TU/mL
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CNY 8,360.00
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CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Product Name | WIBG (PYM1) (NM_001143853) Human Tagged ORF Clone Lentiviral Particle |
| Synonyms | PYM; WIBG |
| Vector | pLenti-C-mGFP |
| ACCN | NM_001143853 |
| ORF Size | 609 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RC227106).
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| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001143853.1, NP_001137325.1 |
| RefSeq ORF | 612 bp |
| Locus ID | 84305 |
| MW | 22.5 kDa |
| Gene Summary | Key regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstream of the exon-exon junction on mRNAs and serves as a positional landmark for the intron exon structure of genes and directs post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) or translation. Acts as an EJC disassembly factor, allowing translation-dependent EJC removal and recycling by disrupting mature EJC from spliced mRNAs. Its association with the 40S ribosomal subunit probably prevents a translation-independent disassembly of the EJC from spliced mRNAs, by restricting its activity to mRNAs that have been translated. Interferes with NMD and enhances translation of spliced mRNAs, probably by antagonizing EJC functions. May bind RNA; the relevance of RNA-binding remains unclear in vivo, RNA-binding was detected by PubMed:14968132, while PubMed:19410547 did not detect RNA-binding activity independently of the EJC.[UniProtKB/Swiss-Prot Function] |
Documents
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