Fam175a (Abraxas1) (NM_001009633) Rat Tagged ORF Clone Lentiviral Particle
CAT#: RR202541L4V
- LentiORF®
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Lenti ORF particles, Fam175a (GFP-tagged ORF) - Rat coiled-coil domain containing 98 (Ccdc98), 200ul, >10^7 TU/mL
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CNY 8,360.00
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规格
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Specifications
Product Data | |
Product Name | Fam175a (Abraxas1) (NM_001009633) Rat Tagged ORF Clone Lentiviral Particle |
Synonyms | Ccdc98; Fam175a; RGD1305287 |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_001009633 |
ORF Size | 1215 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RR202541).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001009633.1 |
RefSeq Size | 1513 bp |
RefSeq ORF | 1218 bp |
Locus ID | 289468 |
Gene Summary | Involved in DNA damage response and double-strand break (DSB) repair. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.[UniProtKB/Swiss-Prot Function] |
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