Human CD200 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CD200
Locus ID	4345
Kit Components	GA102959G1, CD200 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102959G2, CD200 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102959G3, CD200 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001004196, NM_001004197, NM_001318826, NM_001318828, NM_001318830, NM_005944, NM_001365851, NM_001365852, NM_001365853, NM_001365854, NR_158642, NM_001365855
Synonyms	MOX1; MOX2; MRC; OX-2
Summary	This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]

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