Human KALRN activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	KALRN
Locus ID	8997
Kit Components	GA105984G1, KALRN gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105984G2, KALRN gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105984G3, KALRN gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001024660, NM_003947, NM_007064, NR_028136, NM_001322988, NM_001322989, NM_001322990, NM_001322991, NM_001322992, NM_001322993, NM_001322994, NM_001322995, NM_001322996, NM_001322997, NM_001322998, NM_001322999, NM_001323000, NM_001323001
Synonyms	ARHGEF24; CHD5; CHDS5; DUET; DUO; HAPIP; TRAD
Summary	Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with the huntingtin-associated protein 1, which is a huntingtin binding protein that may function in vesicle trafficking. [provided by RefSeq, Apr 2016]

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