Human HJURP activation kit by CRISPRa
CAT#: GA110732
HJURP CRISPRa kit - CRISPR gene activation of human Holliday junction recognition protein
CNY 12,255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | HJURP |
Locus ID | 55355 |
Kit Components | GA110732G1, HJURP gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA110732G2, HJURP gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA110732G3, HJURP gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001282962, NM_001282963, NM_018410 |
Synonyms | FAKTS; hFLEG1; URLC9 |
Summary | Centromeric protein that plays a central role in the incorporation and maintenance of histone H3-like variant CENPA at centromeres. Acts as a specific chaperone for CENPA and is required for the incorporation of newly synthesized CENPA molecules into nucleosomes at replicated centromeres. Prevents CENPA-H4 tetramerization and prevents premature DNA binding by the CENPA-H4 tetramer. Directly binds Holliday junctions.[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN401283 | HJURP - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |