PPAR gamma (PPARG) (NM_138712) Human Mass Spec Standard

CAT#: PH301538

PPARG MS Standard C13 and N15-labeled recombinant protein (NP_619726)



  View other "PPAR gamma" proteins (17)

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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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PPARG rabbit polyclonal antibody
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Specifications

Product Data
Description PPARG MS Standard C13 and N15-labeled recombinant protein (NP_619726)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC201538
Predicted MW 54.7 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_619726
RefSeq Size 1892
RefSeq ORF 1431
Synonyms CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARG5; PPARgamma
Locus ID 5468
Cytogenetics 3p25.2
Summary This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) subfamily of nuclear receptors. PPARs form heterodimers with retinoid X receptors (RXRs) and these heterodimers regulate transcription of various genes. Three subtypes of PPARs are known: PPAR-alpha, PPAR-delta, and PPAR-gamma. The protein encoded by this gene is PPAR-gamma and is a regulator of adipocyte differentiation. Additionally, PPAR-gamma has been implicated in the pathology of numerous diseases including obesity, diabetes, atherosclerosis and cancer. Alternatively spliced transcript variants that encode different isoforms have been described. [provided by RefSeq, Jul 2008]
Protein Families Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
Protein Pathways Huntington's disease, Pathways in cancer, PPAR signaling pathway, Thyroid cancer
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