PAFAH1B3 (NM_001145940) Human Mass Spec Standard

CAT#: PH327237

PAFAH1B3 MS Standard C13 and N15-labeled recombinant protein (NP_001139412)



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CNY 19,520.00


货期*
4周

规格
    • 10 ug

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Purified PAFAH1B3 mouse monoclonal antibody, clone OTI5D2 (formerly 5D2)
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Transient overexpression lysate of platelet-activating factor acetylhydrolase, isoform Ib, subunit 3 (29kDa) (PAFAH1B3), transcript variant 1
    • 100 ug

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Specifications

Product Data
Description PAFAH1B3 MS Standard C13 and N15-labeled recombinant protein (NP_001139412)
Species Human
Expression Host HEK293
Expression cDNA Clone or AA Sequence RC227237
Predicted MW 25.7 kDa
Protein Sequence
Tag C-Myc/DDK
Purity > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration >0.05 µg/µL as determined by microplate BCA method
Labeling Method Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine
Buffer 25 mM Tris-HCl, 100 mM glycine, pH 7.3
Reference Data
RefSeq NP_001139412
RefSeq Size 869
RefSeq ORF 693
Synonyms PAFAHG
Locus ID 5050
Cytogenetics 19q13.2
Summary This gene encodes an acetylhydrolase that catalyzes the removal of an acetyl group from the glycerol backbone of platelet-activating factor. The encoded enzyme is a subunit of the platelet-activating factor acetylhydrolase isoform 1B complex, which consists of the catalytic beta and gamma subunits and the regulatory alpha subunit. This complex functions in brain development. A translocation between this gene on chromosome 19 and the CDC-like kinase 2 gene on chromosome 1 has been observed, and was associated with cognitive disability, ataxia, and atrophy of the brain. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2009]
Protein Families Druggable Genome
Protein Pathways Ether lipid metabolism, Metabolic pathways
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