Glutaredoxin-1 / GLRX1 (1-106) Human Protein
CAT#: AR09116PU-L
Glutaredoxin-1 / GLRX1 (1-106) human recombinant protein, 0.5 mg
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CNY 12,210.00
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规格
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
MAQEFVNCKI QPGKVVVFIK PTCPYCRRAQ EILSQLPIKQ GLLEFVDITA TNHTNEIQDY LQQLTGARTV PRVFIGKDCI GGCSDLVSLQ QSGELLTRLK QIGALQ
|
Predicted MW | 11.7 kDa |
Concentration | lot specific |
Purity | >95% by SDS - PAGE |
Buffer | Presentation State: Purified State: Liquid purified protein Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 1 mM DTT, 10% glycerol |
Preparation | Liquid purified protein |
Protein Description | Recombinant human Glutaredoxin1 protein was expressed in E.coli and purified by using conventional chromatography techniques. |
Storage | Store (in aliquots) at -20°C or -70°C. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Reference Data | |
RefSeq | NP_001112362 |
Locus ID | 2745 |
UniProt ID | P35754, A0A024RAM2 |
Cytogenetics | 5q15 |
Synonyms | GRX; GRX1 |
Summary | This gene encodes a member of the glutaredoxin family. The encoded protein is a cytoplasmic enzyme catalyzing the reversible reduction of glutathione-protein mixed disulfides. This enzyme highly contributes to the antioxidant defense system. It is crucial for several signalling pathways by controlling the S-glutathionylation status of signalling mediators. It is involved in beta-amyloid toxicity and Alzheimer's disease. Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Aug 2011] |
Protein Families | Druggable Genome |
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