CCL1 / I-309 (24-96, His-tag) Human Protein
CAT#: AR09887PU-L
CCL1 / I-309 (24-96, His-tag) human recombinant protein, 0.25 mg
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CNY 17,930.00
货期*
详询
规格
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
MGSSHHHHHH SSGLVPRGSH MKSMQVPFSR CCFSFAEQEI PLRAILCYRN TSSICSNEGL IFKLKRGKEA CALDTVGWVQ RHRKMLRHCP SKRK
|
Tag | His-tag |
Predicted MW | 10.8 kDa |
Concentration | lot specific |
Purity | >85% |
Buffer | Presentation State: Purified Buffer System: 20 mM Tris-HCl buffer (pH 7.5) containing 2 mM DTT, 10% glycerol, 50 mM NaCl |
Protein Description | Recombinant human CCL1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer. |
Storage | Store undiluted at 2-8°C for up to two weeks or (in aliquots) at -20°C or -70°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Reference Data | |
RefSeq | NP_002972 |
Locus ID | 6346 |
UniProt ID | P22362 |
Cytogenetics | 17q12 |
Synonyms | I-309; P500; SCYA1; SISe; TCA3 |
Summary | This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine (C-C motif) receptor 8. [provided by RefSeq, Sep 2014] |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | Chemokine signaling pathway, Cytokine-cytokine receptor interaction |
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