ID1 / BHLHB24 (1-155, His-tag) Human Protein
CAT#: AR50870PU-N
ID1 / BHLHB24 (1-155, His-tag) human recombinant protein, 0.25 mg
Size: 50 ug
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CNY 17,930.00
货期*
详询
规格
Cited in 7 publications. |
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Expression cDNA Clone or AA Sequence |
MGSSHHHHHH SSGLVPRGSH MGSMKVASGS TATAAAGPSC ALKAGKTASG AGEVVRCLSE QSVAISRCAG GAGARLPALL DEQQVNVLLY DMNGCYSRLK ELVPTLPQNR KVSKVEILQH VIDYIRDLQL ELNSESEVGT PGGRGLPVRA PLSTLNGEIS ALTAEAACVP ADDRILCR
|
Tag | His-tag |
Predicted MW | 18.5 kDa |
Concentration | lot specific |
Purity | >85% by SDS - PAGE |
Buffer | Presentation State: Purified State: Liquid purified protein Buffer System: 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1 mM DTT |
Preparation | Liquid purified protein |
Protein Description | Recombinant human ID1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
Storage | Store undiluted at 2-8°C for one week or (in aliquots) at -20°C to -80°C for longer. Avoid repeated freezing and thawing. |
Stability | Shelf life: one year from despatch. |
Reference Data | |
RefSeq | NP_002156 |
Locus ID | 3397 |
UniProt ID | P41134 |
Cytogenetics | 20q11.21 |
Synonyms | bHLHb24; ID |
Summary | The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth, senescence, and differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Protein Families | Druggable Genome, Transcription Factors |
Protein Pathways | TGF-beta signaling pathway |
Citations (7)
The use of this Proteins has been cited in the following citations: |
---|
5-Demethylnobiletin Inhibits Cell Proliferation, Downregulates ID1 Expression, Modulates the NF-κB/TNF-α Pathway and Exerts Antileukemic Effects in AML Cells
,null,
International Journal of Molecular Sciences
,PubMed ID 35806401
[ID1]
|
Citrullinated Inhibitor of DNA Binding 1 Is a Novel Autoantigen in Rheumatoid Arthritis
,null,
Arthritis & Rheumatology (Hoboken, N.j.)
,PubMed ID 30861322
[ID1]
|
microRNA-381 suppresses the growth and increases cisplatin sensitivity in non-small cell lung cancer cells through inhibition of nuclear factor-κB signaling.
,null,
Biomedicine pharmacotherapy = Biomedecine pharmacotherapie
,PubMed ID 29287202
[ID1]
|
CaMKII-mediated Beclin 1 phosphorylation regulates autophagy that promotes degradation of Id and neuroblastoma cell differentiation
,null,
Nature Communications
,PubMed ID 29079782
[ID1]
|
Investigations of Activated ACVR1/ALK2, a Bone Morphogenetic Protein Type I Receptor, That Causes Fibrodysplasia Ossificans Progressiva
,null,
Methods in enzymology
,PubMed ID 21036241
[ID1]
|
COX-2 overexpression increases malignant potential of human glioma cells through Id1
,null,
Oncotarget
,PubMed ID 24659686
[ID1]
|
Contribution of Xanthine Oxidoreductase to Mammary Epithelial and Breast Cancer Cell Differentiation In Part Modulates Inhibitor of Differentiation-1
,null,
Molecular cancer research : MCR
,PubMed ID 21775420
[ID1]
|
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