PLA2G2A (His-tagged Fusion Protein) Human Protein

Specifications

Product Data
Species	Human
Expression Host	E. coli
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) MRGSHHHHHH GMASHMNLVN FHRMIKLTTG KEAALSYGFY GCHCGVGGRG SPKDATDRCC VTHDCCYKRL EKRGCGTKFL SYKFSNSGSR ITCAKQDSCR SQLCECDKAA ATCFARNKTT YNKKYQYYSN KHCRGSTPRC
Tag	His-tag
Concentration	lot specific
Purity	>95%
Buffer	Presentation State: Purified State: Lyophilized purified protein Buffer System: 0.05 M Acetate buffer pH4
Preparation	Lyophilized purified protein
Applications	Western Blot.
Protein Description	Total 140 AA. MW: 15.8 kDa (calculated). N-Terminal His-tag, 16 extra AA (highlighted).
Note	Product is not sterile! Please filter the product by an appropriate sterile filter before using it in the cell cul
Storage	Store lyophilized (preferably in a desiccator) at -20°C and in aliquots at -80°C. Reconstituted antibody can be stored at 4°C for a limited period of time; it does not show decline in activity after two weeks at 4°C. Avoid repeated freezing and thawing.
Stability	Shelf life: one year from despatch.
Reference Data
RefSeq	NP_000291
Locus ID	5320
UniProt ID	P14555
Cytogenetics	1p36.13
Synonyms	PLA2B, PLA2L, RASF-A, NPS-PLA2, Group IIA phospholipase A2, Phospholipase A2 membrane associated
Summary	The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene.[provided by RefSeq, Sep 2009]
Protein Families	Western Blot.
Protein Pathways	alpha-Linolenic acid metabolism, Arachidonic acid metabolism, Ether lipid metabolism, Fc epsilon RI signaling pathway, Glycerophospholipid metabolism, GnRH signaling pathway, Linoleic acid metabolism, Long-term depression, MAPK signaling pathway, Metabolic pathways, Vascular smooth muscle contraction, VEGF signaling pathway

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