Alpha-Synuclein / SNCA (A30P/A53T Mutant) Human Protein
CAT#: SA6003X
Alpha-Synuclein / SNCA (A30P/A53T Mutant) human protein, 0.5 mg
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CNY 12,210.00
货期*
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规格
Specifications
Product Data | |
Species | Human |
Expression Host | E. coli |
Predicted MW | 14.516 kDa |
Purity | >95% |
Buffer | Presentation State: Purified |
Reference Data | |
RefSeq | NP_000336 |
Locus ID | 6622 |
UniProt ID | P37840 |
Cytogenetics | 4q22.1 |
Synonyms | NACP; PARK1; PARK4; PD1 |
Summary | Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. [provided by RefSeq, Feb 2016] |
Protein Families | Druggable Genome |
Protein Pathways | Alzheimer's disease, Parkinson's disease |
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