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AMACR (NM_014324) Human Recombinant Protein
CAT＃: TP313437
Recombinant protein of human alpha-methylacyl-CoA racemase (AMACR), transcript variant 1, 20 µg
View other "AMACR" proteins (8)
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CNY 2,900.00
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| Cited in 1 publication. |
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Specifications
| Product Data | |
| Species | Human |
| Expression Host | HEK293T |
| Expression cDNA Clone or AA Sequence |
>Peptide sequence encoded by RC213437
Blue=ORF Red=Cloning site Green=Tag(s) MALQGISVMELSGLAPGPFCAMVLADFGARVVRVDRPGSRYDVSRLGRGKRSLVLDLKQPRGAAVLRRL CKRSDVLLEPFRRGVMEKLQLGPEILQRENPRLIYARLSGFGQSGSFCRLAGHDINYLALSGVLSKIGR SGENPYAPLNLLADFAGGGLMCALGIIMALFDRTRTDKGQVIDANMVEGTAYLSSFLWKTQKSSLWEAP RGQNMLDGGAPFYTTYRTADGEFMAVGAIEPQFYELLIKGLGLKSDELPNQMSMDDWPEMKKKFADVFA KKTKAEWCQIFDGTDACVTPVLTFEEVVHHDHNKERGSFITSEEQDVSPRPAPLLLNTPAIPSFKRDPF IGEHTEEILEEFGFSREEIYQLNSDKIIESNKVKASL SGPTRTRPLEQKLISEEDLAANDILDYKDDDDKV Recombinant protein using RC213437 also available, TP313437 |
| Tag | C-Myc/DDK |
| Predicted MW | 42.2 kDa |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
| Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Bioactivity | ELISA capture for autoantibodies (PMID: 28191285) |
| Reference Data | |
| RefSeq | NP_055139 |
| Locus ID | 23600 |
| UniProt ID | Q9UHK6 |
| Refseq Size | 2534 |
| Cytogenetics | 5p13.2 |
| Refseq ORF | 1155 |
| Synonyms | AMACRD; CBAS4; P504S; RACE; RM |
| Summary | This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)- and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described. Read-through transcription also exists between this gene and the upstream neighboring C1QTNF3 (C1q and tumor necrosis factor related protein 3) gene. [provided by RefSeq, Mar 2011] |
| Protein Families | Druggable Genome |
| Protein Pathways | Metabolic pathways, Primary bile acid biosynthesis |
Citations (1)
| The use of this Proteins has been cited in the following citations: |
|---|
|
Autoantibodies against oncogenic ERG protein in prostate cancer: potential use in diagnosis and prognosis in a panel with C-MYC, AMACR and HERV-K Gag
,Rastogi, A;Ali, A;Tan, S;Banerjee, S;Chen, Y;Cullen, J;Xavier, CP;Mohamed, AA;Ravindranath, L;Srivastav, J;Young, D;Sesterhenn, IA;Kagan, J;Srivastava, S;McLeod, DG;Rosner, IL;Petrovics, G;Dobi, A;Srivastava, S;Srinivasan, A;,
Genes & Cancer
,PubMed ID 28191285
[AMACR]
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Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC402314 | AMACR HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC404323 | AMACR HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC432989 | AMACR HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LY402314 | Transient overexpression lysate of alpha-methylacyl-CoA racemase (AMACR), nuclear gene encoding mitochondrial protein, transcript variant 1 |
CNY 3,080.00 |
|
| LY404323 | Transient overexpression lysate of alpha-methylacyl-CoA racemase (AMACR), nuclear gene encoding mitochondrial protein, transcript variant 2 |
CNY 3,080.00 |
|
| LY432989 | Transient overexpression lysate of alpha-methylacyl-CoA racemase (AMACR), nuclear gene encoding mitochondrial protein, transcript variant 3 |
CNY 3,080.00 |
|
| PH313437 | AMACR MS Standard C13 and N15-labeled recombinant protein (NP_055139) |
CNY 19,520.00 |
|
| TP760792 | Purified recombinant protein of Human alpha-methylacyl-CoA racemase (AMACR), nuclear gene encoding mitochondrial protein, transcript variant 2, full length, with N-terminal HIS tag, expressed in E. coli, 50ug |
CNY 2,040.00 |
