SNRPN (NM_022805) Human Recombinant Protein
CAT#: TP320680
Recombinant protein of human small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 2, 20 µg
View other "SNRPN" proteins (11)
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Specifications
Product Data | |
Species | Human |
Expression Host | HEK293T |
Expression cDNA Clone or AA Sequence |
>RC220680 protein sequence
Red=Cloning site Green=Tags(s) MTVGKSSKMLQHIDYRMRCILQDGRIFIGTFKAFDKHMNLILCDCDEFRKIKPKNAKQPEREEKRVLGLV LLRGENLVSMTVEGPPPKDTGIARVPLAGAAGGPGVGRAAGRGVPAGVPIPQAPAGLAGPVRGVGGPSQQ VMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPPPVGRATPPPGIMAPPPGMRPPMGPPIGLPPARG TPIGMPPPGMRPPPPGIRGPPPPGMRPPRP TRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Tag | C-Myc/DDK |
Predicted MW | 24.4 kDa |
Concentration | >0.05 µg/µL as determined by microplate BCA method |
Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Buffer | 25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol |
Preparation | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Storage | Store at -80°C. |
Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Reference Data | |
RefSeq | NP_073716 |
Locus ID | 6638 |
UniProt ID | P63162 |
Refseq Size | 1605 |
Cytogenetics | 15q11.2 |
Refseq ORF | 720 |
Synonyms | HCERN3; PWCR; PWS; RT-LI; SM-D; sm-N; SMN; SNRNP-N; SNURF-SNRPN |
Summary | This gene is located within the Prader-Willi Syndrome critical region on chromosome 15 and is imprinted and expressed from the paternal allele. It encodes a component of the small nuclear ribonucleoprotein complex, which functions in pre-mRNA processing and may contribute to tissue-specific alternative splicing. Alternative promoter use and alternative splicing result in a multitude of transcript variants encoding the same protein. Transcript variants that initiate at the CpG island-associated imprinting center may be bicistronic and also encode the SNRPN upstream reading frame protein (SNURF) from an upstream open reading frame. In addition, long spliced transcripts for small nucleolar RNA host gene 14 (SNHG14) may originate from the promoters at this locus and share exons with this gene. Alterations in this region are associated with parental imprint switch failure, which may cause Angelman syndrome or Prader-Willi syndrome. [provided by RefSeq, Mar 2017] |
Protein Families | Stem cell - Pluripotency |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
LC401079 | SNRPN HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LC411550 | SNRPN HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LC411551 | SNRPN HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LC411552 | SNRPN HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LC411553 | SNRPN HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
LY401079 | Transient overexpression lysate of small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 1 |
CNY 3,080.00 |
|
LY411550 | Transient overexpression lysate of small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 2 |
CNY 3,080.00 |
|
LY411551 | Transient overexpression lysate of small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 3 |
CNY 3,080.00 |
|
LY411552 | Transient overexpression lysate of small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 4 |
CNY 3,080.00 |
|
LY411553 | Transient overexpression lysate of small nuclear ribonucleoprotein polypeptide N (SNRPN), transcript variant 5 |
CNY 3,080.00 |
|
PH320680 | SNRPN MS Standard C13 and N15-labeled recombinant protein (NP_073716) |
CNY 19,520.00 |