Zhx2 (NM_199449) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR210894 protein sequence Red=Cloning site Green=Tags(s) MASKRKSTTPCMVRTSQVLEQDMLEEADRAKDKGAGMPQSDVTKDSWAAEPEHSSKETEVVEVKSMGENL SKKLQGGYECKYCPYSTQNLNEFTEHVDMQHPNVILNPLYVCAECNFTTKKYDSLSDHNSKFHPGETNFK LKLIKRNNQTVLEQSIEATNHVVPITASGPGSSDNDPGVSVGKTPMTKTGKLKADAKKVPKKPDEAAPEN HMEGTARLVTDTAEILARLGSVELLQDSLGHVMPSVQLPPNINLVPKVPVPLNTTKYNSALDTNATMINS FNKFPYPTQAELSWLTAASKHPEEHIRIWFATQRLKHGISWSPEEVEEARKKMFNGTIQSVPPTITVLPA QLTPTKVSQPILQTALPCQILGQPSLVLTQVTSGSTTVSCSPITLAVAGVTNHGQKRPLVTPQAAPEPKR PHIAQVPEPPPKVANTPLTPASDRKKTKLQIAHLKASFLQSQFPDDAEVYRLIEVTGLARSEIKKWFSDH RYRCQRGIVHITSESLAKDQMAITGTRHGRTYHVYPDFAPQKFKEKSQGQLKTLEDSFLKSSFPTQAEVE RLRVETKLSRREIDSWFSERRKLRDSMEQAVLDSMGSGKKGSDAVAPNGALSRLDQLSGAQLAGSLPSPS SAIVQNQEQVHLLRSTFARTQWPTPQEYDQLAAKTGLVRTEIVRWFKENRCLLKTGTLSWLEQYQRHHMS DDRGRDAVSRKVAKQVAESPKNGSEAAHQYAKDPKALSEEDSEKLVPRMKVGGDPTKDCLAGKPSEATSD RSEGSRDGQGSEENEESGIVDFVEVTVGEEDAISEKWGSWSRRVAEGTVERADSDSDSTPAEAGQA TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	92.3 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_955520
Locus ID	387609
UniProt ID	Q8C0C0
Refseq Size	4392
Cytogenetics	15 24.01 cM
Refseq ORF	2511
Synonyms	Afr-1; Afr1; mKIAA0854; Raf
Summary	Acts as a transcriptional repressor (PubMed:19515908). Represses the promoter activity of the CDC25C gene stimulated by NFYA (By similarity). May play a role in retinal development where it regulates the composition of bipolar cell populations, by promoting differentiation of bipolar OFF-type cells (PubMed:30146259). In the brain, may promote maintenance and suppress differentiation of neural progenitor cells in the developing cortex (PubMed:19515908).[UniProtKB/Swiss-Prot Function]

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