Dstyk (NM_172516) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR215935 representing NM_172516 Red=Cloning site Green=Tags(s) MEADGQSWAGESVSGPGPGGGGMIRELCRGFSRYRRYLGRLRQNLRETQKFFRDIKCSHSHSCPSSPAGG GAAELGPAGDVAEAPLPAGQLSCISFPPMEETYLQQLVDRLPCILILGQDCNAKCQLLNLLLGVQVLPTL KLDSDESCKLRRLRFTYGTRTRVSLALPGQYELVHTLASHQDNWETIPEEDLEVQEDSEDAAHVLADLEV TMHHALLQEVDIVVAPCPSHRPSVDVLSDLANDFLPVITYALHKDELSERGEQELREVRQYFSFPMFFFK VPKLEIISSSSGRAESERSPLYGQLVDLGYLSSSHRNCVPSDQDCKAQSMLVEQSEKLKQLSTFSHQLLQ NRLVDAAKALNVVHSHCLDIFINQAFDMQRDLQITPKRLEYTRKKENELYESLMNIANRKQEEMKDMIVE TLNTMKEELLDDAANMEFKDVIVPENGETIGTREIKSCIRQIQELIISRLNQAVANKLISSVDYLRESFV GTLERCLQSLEKSQDVSVHITSNYLKQILNAAYHVEVTFHSGSSVTRMLWEQIKQIIQRITWVNPPTITL EWKRKVAQEAIDSLSASKLAKSICSQFRTRLNSSHEAFAASLRQLEAGHSGRLEKTEDLWLKVRKDHAPR LARLSLESRSLQDVLLHRKPKLGQELGRGQYGVVYLCDNWGGHFPCALKSVVPPDEKHWNDLALEFHYMR SLPKHERLVDLHGSVIDYNYGGGSSVAVLLIMERLHRDLYTGLKAGLTLETRLQIALDVVEGIRFLHSQG LVHRDIKLKNVLLDKQNRAKITDLGFCKPEAMMSGSIVGTPIHMAPELFTGKYDNSVDVYAFGILFWYIC SGSIKLPEAFERCASKDHLWNNVRRGTRPERLPVFDEECWQLMEACWDGDPLKRPLLGIVQPMLRSIMDR LCKCSSEQPNRGLDDST TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	105.4 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_766104
Locus ID	213452
UniProt ID	Q6XUX1
Refseq Size	6385
Cytogenetics	1 E4
Refseq ORF	2781
Synonyms	A930019K20Rik; C430014H23Rik; C820013G01; Ripk5
Summary	Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. Involved in the regulation of both caspase-dependent apoptosis and caspase-independent cell death. In the skin, it plays a predominant role in suppressing caspase-dependent apoptosis in response to UV stress in a range of dermal cell types.[UniProtKB/Swiss-Prot Function]

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