Rgs20 (NM_001177795) Mouse Recombinant Protein

Specifications

Product Data
Species	Mouse
Expression Host	HEK293T
Expression cDNA Clone or AA Sequence	Protein Sequence (showhide) >MR219775 representing NM_001177795 Red=Cloning site Green=Tags(s) MPSLSQENQGYLEEHLTRQAAQAQLLPLFRAEKDYNPSIDQDTEDKEGSQAVTGVKLPDSTGSTHFATFL ACSPAVLVSSAATPSRGLPGRRDFPSQPSSWPTAWLSPEPHRLLFLLVASMALPGRRPRGRLLKLASPNS EPRGEDACTEKSSPESPEGSERTEMRMRQMCGGSETQGPAPSQQGGRGSNACCFCWCCCCTCSCLTVRNQ EDQRPQRASHEIRTDIPACEESPTPTLEEVCAWAQSFDNLMVTPAGRNAFREFLRTEFSEENMLFWMACE ELKREANKSTIEEKARIIYEDYISILSPKEVSLDSRVREVINRNMVDPSQHIFDDAQLQIYTLMHRDSYP RFMNSTVYKDLLTSLAEKTVEA TRTRPLEQKLISEEDLAANDILDYKDDDDKV
Tag	C-MYC/DDK
Predicted MW	41.7 kDa
Concentration	>0.05 µg/µL as determined by microplate BCA method
Purity	> 80% as determined by SDS-PAGE and Coomassie blue staining
Buffer	25 mM Tris-HCl, 100 mM glycine, pH 7.3, 10% glycerol
Note	For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process.
Storage	Store at -80°C after receiving vials.
Stability	Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
Reference Data
RefSeq	NP_001171266
Locus ID	58175
UniProt ID	Q8C5J7, E9Q720
Refseq Size	2125
Cytogenetics	1 A1
Refseq ORF	1116
Synonyms	2900073E09Rik; Rgsz1
Summary	Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds selectively to G(z)-alpha and G(alpha)-i2 subunits, accelerates their GTPase activity and regulates their signaling activities. The G(z)-alpha activity is inhibited by the phosphorylation and palmitoylation of the G-protein. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins.[UniProtKB/Swiss-Prot Function]

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