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FGFR1 (NM_023110) Human Recombinant Protein
CAT＃: TP700118
Purified recombinant protein of Human fibroblast growth factor receptor 1, transcript variant 1, with C-terminal DDK/His tag, expressed in human cells
View other "FGFR1" proteins (22)
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CNY 6,650.00
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CNY 1,999.00
CNY 2,700.00
Specifications
| Product Data | |
| Species | Human |
| Expression Host | HEK293T |
| Expression cDNA Clone or AA Sequence |
A DNA sequence from TrueORF clone, RC600018, encoding the extracellular domain (Arg22-Glu376) of human FGFR1 transcript variant 1
|
| Tag | C-DDK/His |
| Predicted MW | 42 Kda |
| Concentration | >0.05 µg/µL as determined by microplate BCA method |
| Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Buffer | PBS, pH 7.4, 10% glycerol |
| Note | For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
| Storage | Store at -80°C. |
| Stability | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
| Reference Data | |
| RefSeq | NP_075598 |
| Locus ID | 2260 |
| UniProt ID | P11362 |
| Refseq Size | 5917 |
| Cytogenetics | 8p11.23 |
| Refseq ORF | 1128 |
| Synonyms | bFGF-R-1; BFGFR; CD331; CEK; ECCL; FGFBR; FGFR-1; FLG; FLT-2; FLT2; HBGFR; HH2; HRTFDS; KAL2; N-SAM; OGD |
| Summary | The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized. [provided by RefSeq, Jul 2008] |
| Protein Families | Druggable Genome, Protein Kinase, Transmembrane |
| Protein Pathways | Adherens junction, MAPK signaling pathway, Melanoma, Pathways in cancer, Prostate cancer, Regulation of actin cytoskeleton |
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Resources
| 蛋白相关资源 |
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| LC402963 | FGFR1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC411517 | FGFR1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1,470.00 |
|
| LC411518 | FGFR1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC411519 | FGFR1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 900.00 |
|
| LC414376 | FGFR1 HEK293T cell transient overexpression lysate (as WB positive control) |
CNY 1,470.00 |
|
| LY402963 | Transient overexpression lysate of fibroblast growth factor receptor 1 (FGFR1), transcript variant 1 |
CNY 3,080.00 |
|
| LY411517 | Transient overexpression lysate of fibroblast growth factor receptor 1 (FGFR1), transcript variant 4 |
CNY 4,840.00 |
|
| LY411518 | Transient overexpression lysate of fibroblast growth factor receptor 1 (FGFR1), transcript variant 5 |
CNY 3,080.00 |
|
| LY411519 | Transient overexpression lysate of fibroblast growth factor receptor 1 (FGFR1), transcript variant 6 |
CNY 3,080.00 |
|
| LY414376 | Transient overexpression lysate of fibroblast growth factor receptor 1 (FGFR1), transcript variant 2 |
CNY 4,840.00 |
|
| PH302080 | FGFR1 MS Standard C13 and N15-labeled recombinant protein (NP_075598) |
CNY 19,520.00 |
|
| PH312579 | FGFR1 MS Standard C13 and N15-labeled recombinant protein (NP_075595) |
CNY 19,520.00 |
|
| PH314979 | FGFR1 MS Standard C13 and N15-labeled recombinant protein (NP_075596) |
CNY 14,250.00 |
|
| PH320009 | FGFR1 MS Standard C13 and N15-labeled recombinant protein (NP_075594) |
CNY 19,520.00 |
|
| TP302080 | Recombinant protein of human fibroblast growth factor receptor 1 (FGFR1), transcript variant 1, 20 µg |
CNY 2,900.00 |
|
| TP312579 | Recombinant protein of human fibroblast growth factor receptor 1 (FGFR1), transcript variant 5, 20 µg |
CNY 2,900.00 |
|
| TP314979 | Purified recombinant protein of Homo sapiens fibroblast growth factor receptor 1 (FGFR1), transcript variant 6, 20 µg |
CNY 2,900.00 |
|
| TP320009 | Recombinant protein of human fibroblast growth factor receptor 1 (FGFR1), transcript variant 4, 20 µg |
CNY 2,900.00 |
|
| TP700119 | Purified recombinant protein of human fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) (FGFR1), transcript variant 2, with C-terminal DDK/His tag, expressed in human cells, 20 µg |
CNY 6,650.00 |
|
| TP700120 | Purified recombinant protein of human fibroblast growth factor receptor 1 (fms-related tyrosine kinase 2, Pfeiffer syndrome) (FGFR1), transcript variant 3, with C-terminal DDK/His tag, expressed in human cells, 20 µg |
CNY 6,650.00 |
|
| TP710005 | Recombinant protein of human fibroblast growth factor receptor 1 (FGFR1),residues 1-376 polyhistidine tag, expressed in sf9 cell |
CNY 4,020.00 |
|
| TP710236 | Purified recombinant protein of Human fibroblast growth factor receptor 1 (FGFR1), transcript variant 1, residues 1-376aa, secretory expressed, with C-terminal HIS tag, expressed in sf9, 20ug |
CNY 4,020.00 |
